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In silico design and optimization of new materials primarily relies on high-accuracy atomic simulators that perform density functional theory (DFT) calculations. While recent works showcase the strong potential of machine learning to…

Machine Learning · Computer Science 2025-09-30 Prashant Govindarajan , Mathieu Reymond , Antoine Clavaud , Mariano Phielipp , Santiago Miret , Sarath Chandar

Novel materials drive advancements in fields ranging from energy storage to electronics, with crystal structure characterization forming a crucial yet challenging step in materials discovery. In this work, we introduce \emph{deCIFer}, an…

Deep clustering methods improve the performance of clustering tasks by jointly optimizing deep representation learning and clustering. While numerous deep clustering algorithms have been proposed, most of them rely on artificially…

Machine Learning · Computer Science 2024-01-30 Zhanwen Cheng , Feijiang Li , Jieting Wang , Yuhua Qian

The stability of chemically complex nanoparticles is governed by an immense configurational space arising from heterogeneous local atomic environments across surface and interior regions. Efficiently identifying low-energy configurations…

We consider the degree-Rips construction from topological data analysis, which provides a density-sensitive, multiparameter hierarchical clustering algorithm. We analyze its stability to perturbations of the input data using the…

Statistics Theory · Mathematics 2025-06-24 Alexander Rolle , Luis Scoccola

Learning manipulable representations of the world and its dynamics is central to AI. Joint-Embedding Predictive Architectures (JEPAs) offer a promising blueprint, but lack of practical guidance and theory has led to ad-hoc R&D. We present a…

Machine Learning · Computer Science 2025-11-17 Randall Balestriero , Yann LeCun

The increased time- and length-scale of classical molecular dynamics simulations have led to raw data flows surpassing storage capacities, necessitating on-the-fly integration of structural analysis algorithms. As a result, algorithms must…

Stability of cylindrical and spherical crystals growing from a supersaturated solution (in Mullins-Sekerka's approximation) is considered using the maximum entropy production principle. The concept of the binodal of the nonequilibrium…

Pattern Formation and Solitons · Physics 2016-09-07 L. M. Martiouchev , V. D. Seleznev , I. E. Kuznetsova

Accurate determination of crystal structures is central to materials science, underpinning the understanding of composition-structure-property relationships and the discovery of new materials. Powder X-ray diffraction is a key technique in…

Materials Science · Physics 2026-03-20 Chenlei Xu , Tianhao Su , Jie Xiong , Yue Wu , Shuya Dong , Tian Jiang , Mengwei He , Shuai Chen , Tong-Yi Zhang

Single-cell foundation models learn by reconstructing masked gene expression, implicitly treating technical noise as signal. With dropout rates exceeding 90%, reconstruction objectives encourage models to encode measurement artifacts rather…

Computational Engineering, Finance, and Science · Computer Science 2026-02-03 Ali ElSheikh , Rui-Xi Wang , Weimin Wu , Yibo Wen , Payam Dibaeinia , Jennifer Yuntong Zhang , Jerry Yao-Chieh Hu , Mei Knudson , Sudarshan Babu , Shao-Hua Sun , Aly A. Khan , Han Liu

A central problem of materials science is to determine whether a hypothetical material is stable without being synthesized, which is mathematically equivalent to a global optimization problem on a highly non-linear and multi-modal potential…

Applications · Statistics 2023-05-02 Arvind Krishna , Huan Tran , Chaofan Huang , Rampi Ramprasad , V. Roshan Joseph

Materials discovery requires navigating vast chemical and structural spaces while satisfying multiple, often conflicting, objectives. We present LLM-guided Evolution for MAterials discovery (LLEMA), a unified framework that couples the…

Machine Learning · Computer Science 2026-03-06 Nikhil Abhyankar , Sanchit Kabra , Saaketh Desai , Chandan K. Reddy

Organic molecular crystals underpin technologies ranging from pharmaceuticals to organic electronics, yet predicting solid-state packing of molecules remains challenging because candidate generation is combinatorial and stability is only…

Efficiently and accurately determining the symmetry is a crucial step in the structural analysis of crystalline materials. Existing methods usually mindlessly apply deep learning models while ignoring the underlying chemical rules. More…

Machine Learning · Computer Science 2025-11-11 Liheng Yu , Zhe Zhao , Xucong Wang , Di Wu , Pengkun Wang

In recent advancements in unsupervised visual representation learning, the Joint-Embedding Predictive Architecture (JEPA) has emerged as a significant method for extracting visual features from unlabeled imagery through an innovative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Shentong Mo , Shengbang Tong

Stable diffusion models represent the state-of-the-art in data synthesis across diverse domains and hold transformative potential for applications in science and engineering, e.g., by facilitating the discovery of novel solutions and…

Machine Learning · Computer Science 2025-10-23 Stefano Zampini , Jacob K. Christopher , Luca Oneto , Davide Anguita , Ferdinando Fioretto

Molecular crystal structure prediction represents a grand challenge in computational chemistry due to large sizes of constituent molecules and complex intra- and intermolecular interactions. While generative modeling has revolutionized…

Crystalline materials, with symmetrical and periodic structures, exhibit a wide spectrum of properties and have been widely used in numerous applications across electronics, energy, and beyond. For crystalline materials discovery,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-11 Zhenzhong Wang , Haowei Hua , Wanyu Lin , Ming Yang , Kay Chen Tan

Crystal property prediction is a crucial aspect of developing novel materials. However, there are two technical challenges to be addressed for speeding up the investigation of crystals. First, labeling crystal properties is intrinsically…

Machine Learning · Computer Science 2023-06-12 Haomin Yu , Yanru Song , Jilin Hu , Chenjuan Guo , Bin Yang

Geometric information such as the space groups and crystal systems plays an important role in the properties of crystal materials. Prediction of crystal system and space group thus has wide applications in crystal material property…

Materials Science · Physics 2021-05-18 Yuxin Li , Rongzhi Dong , Wenhui Yang , Jianjun Hu