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While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

Microscopic evaluation of white blood cell morphology is central to leukemia diagnosis, yet current deep learning models often act as black boxes, limiting clinical trust and adoption. We introduce HemBLIP, a vision language model designed…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Julie van Logtestijn , Petru Manescu

We propose a novel approach to identify one of the most significant dermoscopic criteria in the diagnosis of Cutaneous Melanoma: the Blue-whitish structure. In this paper, we achieve this goal in a Multiple Instance Learning framework using…

Computer Vision and Pattern Recognition · Computer Science 2015-07-01 Ali Madooei , Mark S. Drew , Hossein Hajimirsadeghi

Existing studies for automated melanoma diagnosis are based on single-time point images of lesions. However, melanocytic lesions de facto are progressively evolving and, moreover, benign lesions can progress into malignant melanoma.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-22 Zhen Yu , Jennifer Nguyen , Xiaojun Chang , John Kelly , Catriona Mclean , Lei Zhang , Victoria Mar , Zongyuan Ge

creating automated processes in different areas of medical science with the application of engineering tools is a highly growing field over recent decades. In this context, many medical image processing and analyzing researchers use…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Hamed Talebi , Amin Ranjbar , Alireza Davoudi , Hamed Gholami , Mohammad Bagher Menhaj

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Reliable large-scale cell detection and segmentation is the fundamental first step to understanding biological processes in the brain. The ability to phenotype cells at scale can accelerate preclinical drug evaluation and system-level brain…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Son T. Ly , Bai Lin , Hung Q. Vo , Dragan Maric , Badri Roysam , Hien V. Nguyen

Semi-supervised semantic segmentation focuses on the exploration of a small amount of labeled data and a large amount of unlabeled data, which is more in line with the demands of real-world image understanding applications. However, it is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Bo Dang , Yansheng Li , Yongjun Zhang , Jiayi Ma

Convolution Neural Networks (CNN) have performed well in many applications such as object detection, pattern recognition, video surveillance and so on. CNN carryout feature extraction on labelled data to perform classification. Multi-label…

Machine Learning · Computer Science 2021-01-28 Tolulope A. Odetola , Ogheneuriri Oderhohwo , Syed Rafay Hasan

Partially-supervised learning can be challenging for segmentation due to the lack of supervision for unlabeled structures, and the methods directly applying fully-supervised learning could lead to incompatibility, meaning ground truth is…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Ke Zhang , Xiahai Zhuang

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

Graph property prediction tasks are important and numerous. While each task offers a small size of labeled examples, unlabeled graphs have been collected from various sources and at a large scale. A conventional approach is training a model…

Machine Learning · Computer Science 2023-10-13 Gang Liu , Eric Inae , Tong Zhao , Jiaxin Xu , Tengfei Luo , Meng Jiang

To reduce the human annotation efforts, the programmatic weak supervision (PWS) paradigm abstracts weak supervision sources as labeling functions (LFs) and involves a label model to aggregate the output of multiple LFs to produce training…

Machine Learning · Computer Science 2023-03-09 Renzhi Wu , Shen-En Chen , Jieyu Zhang , Xu Chu

Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine learning models, or heuristic-based iterative…

Genomics · Quantitative Biology 2025-09-12 Meng Xiao , Weiliang Zhang , Xiaohan Huang , Hengshu Zhu , Min Wu , Xiaoli Li , Yuanchun Zhou

Chip-based Evanescent Light Scattering (cELS) utilizes the multiple modes of a high-index contrast optical waveguide for near-field illumination of unlabeled samples, thereby repositioning the highest spatial frequencies of the sample into…

Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlying learning and memory. Yet, the unique behavioral properties…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Mikhail E. Kandel , Eunjae Kim , Young Jae Lee , Gregory Tracy , Hee Jung Chung , Gabriel Popescu

Pixel-level analysis of blood images plays a pivotal role in diagnosing blood-related diseases, especially Anaemia. These analyses mainly rely on an accurate diagnosis of morphological deformities like shape, size, and precise pixel…

Image and Video Processing · Electrical Eng. & Systems 2022-02-11 Muhammad Shahzad , Arif Iqbal Umar , Syed Hamad Shirazi , Israr Ahmed Shaikh

As advanced image manipulation techniques emerge, detecting the manipulation becomes increasingly important. Despite the success of recent learning-based approaches for image manipulation detection, they typically require expensive…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yuanhao Zhai , Tianyu Luan , David Doermann , Junsong Yuan
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