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The human brain is organized in functional modules. Such an organization presents a basic conundrum: modules ought to be sufficiently independent to guarantee functional specialization and sufficiently connected to bind multiple processors…

Biological Physics · Physics 2015-05-27 Lazaros K. Gallos , Hernan A. Makse , Mariano Sigman

We typically think of cells as responding to external signals independently by regulating their gene expression levels, yet they often locally exchange information and coordinate. Can such spatial coupling be of benefit for conveying…

Molecular Networks · Quantitative Biology 2015-01-19 Thomas R. Sokolowski , Gašper Tkačik

Neuromorphic computing leveraging spiking neural network has emerged as a promising solution to tackle the security and reliability challenges with the conventional cyber-physical infrastructure of microgrids. Its event-driven paradigm…

Emerging Technologies · Computer Science 2024-08-13 Yubo Song , Subham Sahoo , Xiaoguang Diao

Complex networks usually exhibit a rich architecture organized over multiple intertwined scales. Information pathways are expected to pervade these scales reflecting structural insights that are not manifest from analyses of the network…

Physics and Society · Physics 2022-09-16 Pablo Villegas , Andrea Gabrielli , Francesca Santucci , Guido Caldarelli , Tommaso Gili

Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context specific and dynamic in…

Molecular Networks · Quantitative Biology 2014-02-20 Ye Tian , Bai Zhang , Eric P. Hoffman , Robert Clarke , Zhen Zhang , Ie-Ming Shih , Jianhua Xuan , David M. Herrington , Yue Wang

Biological information processing is often carried out by complex networks of interconnected dynamical units. A basic question about such networks is that of reliability: if the same signal is presented many times with the network in…

Chaotic Dynamics · Physics 2015-06-11 Guillaume Lajoie , Kevin K. Lin , Eric Shea-Brown

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

Many embedded real-time control systems suffer from resource constraints and dynamic workload variations. Although optimal feedback scheduling schemes are in principle capable of maximizing the overall control performance of multitasking…

Other Computer Science · Computer Science 2008-12-18 Feng Xia , Yu-Chu Tian , Youxian Sun , Jinxiang Dong

Short-term changes in efficacy have been postulated to enhance the ability of synapses to transmit information between neurons, and within neuronal networks. Even at the level of connections between single neurons, direct confirmation of…

Neurons and Cognition · Quantitative Biology 2012-04-30 Pat Scott , Anna I. Cowan , Christian Stricker

Transitional accounts of evolution emphasise a few changes that shape what is evolvable, with dramatic consequences for derived lineages. More recently it has been proposed that cognition might also have evolved via a series of major…

Artificial Intelligence · Computer Science 2025-09-18 Konstantinos Voudouris , Andrew Barron , Marta Halina , Colin Klein , Matishalin Patel

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

Cortical circuits exhibit high levels of response diversity, even across apparently uniform neuronal populations. While emerging data-driven approaches exploit this heterogeneity to infer effective models of cortical circuit computation…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mohammadreza Soltanipour , Stefan Treue , Fred Wolf

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

The effectiveness of recurrent neural networks can be largely influenced by their ability to store into their dynamical memory information extracted from input sequences at different frequencies and timescales. Such a feature can be…

Machine Learning · Computer Science 2020-07-01 Antonio Carta , Alessandro Sperduti , Davide Bacciu

Cortical plasticity is one of the main features that enable our ability to learn and adapt in our environment. Indeed, the cerebral cortex self-organizes itself through structural and synaptic plasticity mechanisms that are very likely at…

Neural and Evolutionary Computing · Computer Science 2020-09-03 Lyes Khacef , Laurent Rodriguez , Benoit Miramond

The release of large datasets and developments in AI have led to dramatic improvements in decoding methods that reconstruct seen images from human brain activity. We evaluate the prospect of further improving recent decoding methods by…

Neurons and Cognition · Quantitative Biology 2023-12-14 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

The current leading computer vision models are typically feed forward neural models, in which the output of one computational block is passed to the next one sequentially. This is in sharp contrast to the organization of the primate visual…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Barak Battash , Lior Wolf

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

Neurons and Cognition · Quantitative Biology 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

Biological information processing manifests a huge variety in its complexity and capability among different organisms, which presumably stems from the evolutionary optimization under limited computational resources. Starting from the…

Biological Physics · Physics 2025-10-21 Takehiro Tottori , Tetsuya J. Kobayashi

Hub structure, characterized by a few highly interconnected nodes surrounded by a larger number of nodes with fewer connections, is a prominent topological feature of biological brains, contributing to efficient information transfer and…

Machine Learning · Computer Science 2023-07-06 Zhaoze Wang , Junsong Wang