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Numerous deep learning-based solutions have been developed for the automatic recognition of breast cancer using mammography images. However, their performance often declines when applied to data from different domains, primarily due to…

Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Numan Saeed , Shahad Hardan , Muhammad Ridzuan , Nada Saadi , Karthik Nandakumar , Mohammad Yaqub

Background: Despite high in-silico performance (AUC >0.80), 85% of AI cancer biomarkers fail clinical translation, exposing a critical algorithm-to-outcome gap. Methods: We introduce the Algorithm-to-Outcome Concordance (AOC) framework,…

Quantitative Methods · Quantitative Biology 2026-01-06 Xiyao Yu , Kai Fu

Machine learning provides a broad framework for addressing high-dimensional prediction problems in classification and regression. While machine learning is often applied for imaging problems in medical physics, there are many efforts to…

Applications · Statistics 2020-07-02 John Kang , James T. Coates , Robert L. Strawderman , Barry S. Rosenstein , Sarah L. Kerns

Objectives: To compare artificial intelligence (AI) as a second reader in detecting lung nodules on chest X-rays (CXR) versus radiologists of two binational institutions, and to evaluate AI performance when using two different modes:…

Purpose: This study examines the core traits of image-to-image translation (I2I) networks, focusing on their effectiveness and adaptability in everyday clinical settings. Methods: We have analyzed data from 794 patients diagnosed with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Mohammad R. Salmanpour , Amin Mousavi , Yixi Xu , William B Weeks , Ilker Hacihaliloglu

In this paper, we address the problem of interference alignment (IA) over MIMO interference channels with limited channel state information (CSI) feedback based on quantization codebooks. Due to limited feedback and hence imperfect IA,…

Information Theory · Computer Science 2015-06-18 Xiaoming Chen , Chau Yuen

Multiparametric radiological imaging is vital for detection, characterization and diagnosis of many different diseases. The use of radiomics for quantitative extraction of textural features from radiological imaging is increasing moving…

Computer Vision and Pattern Recognition · Computer Science 2020-02-07 Vishwa S. Parekh , Michael A. Jacobs

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…

Quantitative Methods · Quantitative Biology 2024-12-17 Suchithra Kunhoth , Somaya Al- Maadeed , Younes Akbari , Rafif Al Saady

Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical…

Artificial Intelligence · Computer Science 2024-06-17 Tristen Pool , Dennis Trujillo

Foundational vision transformer models have shown impressive few shot performance on many vision tasks. This research presents a novel investigation into the application of parameter efficient fine-tuning methods within an active learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Athmanarayanan Lakshmi Narayanan , Ranganath Krishnan , Amrutha Machireddy , Mahesh Subedar

Aim: provide a methodological framework for the process of clinical tests, clinical acceptance, and scientific assessment of algorithms and software based on the artificial intelligence (AI) technologies. Clinical tests are considered as a…

Artificial intelligence (AI) is showing promise in improving clinical diagnosis. In breast cancer screening, recent studies show that AI has the potential to improve early cancer diagnosis and reduce unnecessary workup. As the number of…

Medical images differ from natural images in significantly higher resolutions and smaller regions of interest. Because of these differences, neural network architectures that work well for natural images might not be applicable to medical…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Kangning Liu , Sudarshini Tyagi , Laura Heacock , S. Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Lung cancer patients frequently experience breakthrough pain episodes, with up to 91% requiring timely intervention. To enable proactive pain management, we propose a hybrid machine learning and large language model pipeline that predicts…

Artificial Intelligence · Computer Science 2026-05-22 Yipeng Zhuang , Yifeng Guo , Yuewen Li , Yuheng Wu , Philip Leung-Ho Yu , Tingting Song , Zhiyong Wang , Kunzhong Zhou , Weifang Wang , Li Zhuang

Carcinogenesis is a proteiform phenomenon, with tumors emerging in various locations and displaying complex, diverse shapes. At the crucial intersection of research and clinical practice, it demands precise and flexible assessment. However,…

Artificial intelligence (AI) systems increasingly achieve expert-level predictive accuracy in healthcare, yet improvements in model performance often fail to produce corresponding gains in patient outcomes. We term this disconnect the…

Artificial Intelligence · Computer Science 2026-01-13 Rifa Ferzana

The de facto standard of dynamic histogram binning for radiomic feature extraction leads to an elevated sensitivity to fluctuations in annotated regions. This may impact the majority of radiomic studies published recently and contribute to…

Image and Video Processing · Electrical Eng. & Systems 2022-11-11 Darryl E. Wright , Cole Cook , Jason Klug , Panagiotis Korfiatis , Timothy L. Kline

Objective: Although medical imaging datasets are increasingly available, abnormal and annotation-intensive findings critical to lung cancer screening, particularly small pulmonary nodules, remain underrepresented and inconsistently curated.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Fakrul Islam Tushar , Ehsan Samei , Cynthia Rudin , Joseph Y. Lo

Accurately predicting immunotherapy response in Non-Small Cell Lung Cancer (NSCLC) remains a critical unmet need. Existing radiomics and deep learning-based predictive models rely primarily on pre-treatment imaging to predict categorical…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Judy Huang , Amna F. Sher , Gagandeep Singh , Chao Chen , Prateek Prasanna