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Large language models (LLMs) are increasingly used for medical consultation and health information support. In this high-stakes setting, safety depends not only on medical knowledge, but also on how models respond when patient inputs are…

Computation and Language · Computer Science 2026-04-01 Yahan Li , Xinyi Jie , Wanjia Ruan , Xubei Zhang , Huaijie Zhu , Yicheng Gao , Chaohao Du , Ruishan Liu

Automated release note generation addresses the challenge of documenting frequent software updates, where manual efforts are time-consuming and prone to human error. Although recent advances in language models further enhance this process,…

Software Engineering · Computer Science 2025-11-05 Qianru Meng , Zhaochun Ren , Joost Visser

Large language models (LLMs) often match or exceed clinician-level performance on medical benchmarks, yet very few are evaluated on real clinical data or examined beyond headline metrics. We present, to our knowledge, the first evaluation…

Existing LLM-as-a-Judge approaches for evaluating text generation suffer from rating inconsistencies, with low agreement and high rating variance across different evaluator models. We attribute this to subjective evaluation criteria…

Computation and Language · Computer Science 2025-11-04 Yukyung Lee , Joonghoon Kim , Jaehee Kim , Hyowon Cho , Jaewook Kang , Pilsung Kang , Najoung Kim

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Large Multimodal Models (LMMs) exhibit impressive cross-modal understanding and reasoning abilities, often assessed through multiple-choice questions (MCQs) that include an image, a question, and several options. However, many benchmarks…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Jinsheng Huang , Liang Chen , Taian Guo , Fu Zeng , Yusheng Zhao , Bohan Wu , Ye Yuan , Haozhe Zhao , Zhihui Guo , Yichi Zhang , Jingyang Yuan , Wei Ju , Luchen Liu , Tianyu Liu , Baobao Chang , Ming Zhang

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

To protect patient safety, modern pharmaceutical complexity demands strict prescription verification. We offer a new approach - Rx Strategist - that makes use of knowledge graphs and different search strategies to enhance the power of Large…

Computation and Language · Computer Science 2024-09-06 Phuc Phan Van , Dat Nguyen Minh , An Dinh Ngoc , Huy Phan Thanh

LLMs have achieved strong results on both function-level code synthesis and repository-level code modification, yet a capability that falls between these two extremes -- compositional code creation, i.e., building a complete, internally…

Software Engineering · Computer Science 2026-04-30 Yeheng Chen , Chaoxiang Xie , Yuling Shi , Wenhao Zeng , Yongpan Wang , Hongyu Zhang , Xiaodong Gu

Molecular relational learning (MRL) is crucial for understanding the interaction behaviors between molecular pairs, a critical aspect of drug discovery and development. However, the large feasible model space of MRL poses significant…

Machine Learning · Computer Science 2024-10-22 Sizhe Liu , Jun Xia , Lecheng Zhang , Yuchen Liu , Yue Liu , Wenjie Du , Zhangyang Gao , Bozhen Hu , Cheng Tan , Hongxin Xiang , Stan Z. Li

General large language models enhanced with supervised fine-tuning and reinforcement learning from human feedback are increasingly popular in academia and industry as they generalize foundation models to various practical tasks in a prompt…

Computation and Language · Computer Science 2024-06-18 Shiguo Lian , Kaikai Zhao , Xinhui Liu , Xuejiao Lei , Bikun Yang , Wenjing Zhang , Kai Wang , Zhaoxiang Liu

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

We introduce PhysicianBench, a benchmark for evaluating LLM agents on physician tasks grounded in real clinical setting within electronic health record (EHR) environments. Existing medical agent benchmarks primarily focus on static…

Medication recommendation predicts medications for patient visits, but existing methods still face two key challenges. At the model level, traditional drug recommendation methods only predict structured drug codes with limited evidence…

Computation and Language · Computer Science 2026-05-29 Xinyu Wang , Hanwei Wu , Zhenghan Tai , Sicheng Lyu , Qincheng Lu , Ziyu Zhao , Jijun Chi , Jingrui Tian , Xiao-Wen Chang , Ziyang Song

Evaluating Large Language Models (LLMs) in the mental health domain poses distinct challenged from other domains, given the subtle and highly subjective nature of symptoms that exhibit significant variability among individuals. This paper…

Computation and Language · Computer Science 2024-06-04 Haoan Jin , Siyuan Chen , Dilawaier Dilixiati , Yewei Jiang , Mengyue Wu , Kenny Q. Zhu

One core capability of Large Language Models (LLMs) is to follow natural language instructions. However, the evaluation of such abilities is not standardized: Human evaluations are expensive, slow, and not objectively reproducible, while…

Computation and Language · Computer Science 2023-11-15 Jeffrey Zhou , Tianjian Lu , Swaroop Mishra , Siddhartha Brahma , Sujoy Basu , Yi Luan , Denny Zhou , Le Hou

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng
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