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Autonomous coding agents built on large language models (LLMs) can now solve many general software and machine learning tasks, but they remain ineffective on complex, domain-specific scientific problems. Medical imaging is a particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Roshan Kenia , Xiaoman Zhang , Pranav Rajpurkar

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Machine Reading Comprehension (MRC) is an essential task in evaluating natural language understanding. Existing MRC datasets primarily assess specific aspects of reading comprehension (RC), lacking a comprehensive MRC benchmark. To fill…

Computation and Language · Computer Science 2025-03-11 Shengkun Ma , Hao Peng , Lei Hou , Juanzi Li

Recently, there has been growing interest in extending the context length of large language models (LLMs), aiming to effectively process long inputs of one turn or conversations with more extensive histories. While proprietary models such…

Computation and Language · Computer Science 2023-10-05 Chenxin An , Shansan Gong , Ming Zhong , Xingjian Zhao , Mukai Li , Jun Zhang , Lingpeng Kong , Xipeng Qiu

The ability of Large Language Models (LLMs) to precisely follow complex and fine-grained lexical instructions is a cornerstone of their utility and controllability. However, evaluating this capability remains a significant challenge.…

Computation and Language · Computer Science 2026-03-24 Huimin Ren , Yan Liang , Baiqiao Su , Chaobo Sun , Hengtong Lu , Kaike Zhang , Chen Wei

The instruction hierarchy, which establishes a priority order from system messages to user messages, conversation history, and tool outputs, is essential for ensuring consistent and safe behavior in language models (LMs). Despite its…

Reliable epidemiological reasoning requires synthesizing study evidence to infer disease burden, transmission dynamics, and intervention effects at the population level. Existing medical question answering benchmarks primarily emphasize…

Computation and Language · Computer Science 2026-05-27 Mingyang Wei , Dehai Min , Zewen Liu , Yuzhang Xie , Guanchen Wu , Ziyang Zhang , Carl Yang , Max S. Y. Lau , Qi He , Lu Cheng , Wei Jin

Large Language Models (LLMs) are predominantly assessed based on their common sense reasoning, language comprehension, and logical reasoning abilities. While models trained in specialized domains like mathematics or coding have demonstrated…

Software Engineering · Computer Science 2026-01-08 Danny Brahman , Mohammad Mahoor

The effective assessment of the instruction-following ability of large language models (LLMs) is of paramount importance. A model that cannot adhere to human instructions might be not able to provide reliable and helpful responses. In…

Computation and Language · Computer Science 2023-11-17 Yimin Jing , Renren Jin , Jiahao Hu , Huishi Qiu , Xiaohua Wang , Peng Wang , Deyi Xiong

Patients are increasingly using large language models (LLMs) to seek answers to their healthcare-related questions. However, benchmarking efforts in LLMs for question answering often focus on medical exam questions, which differ…

Computation and Language · Computer Science 2026-03-19 Raymond Xiong , Furong Jia , Lionel Wong , Monica Agrawal

We introduce MultiMedEval, an open-source toolkit for fair and reproducible evaluation of large, medical vision-language models (VLM). MultiMedEval comprehensively assesses the models' performance on a broad array of six multi-modal tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Corentin Royer , Bjoern Menze , Anjany Sekuboyina

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Incorporating large language models (LLMs) in medical question answering demands more than high average accuracy: a model that returns substantively different answers each time it is queried is not a reliable medical tool. Online health…

Information Retrieval · Computer Science 2026-04-14 Avi-ad Avraam Buskila

Large Language models have achieved impressive performance in automated software engineering. Extensive efforts have been made to evaluate the abilities of code LLMs in various aspects, with an increasing number of benchmarks and evaluation…

Software Engineering · Computer Science 2025-03-25 Lezhi Ma , Shangqing Liu , Lei Bu , Shangru Li , Yida Wang , Yang Liu

Large Language Models (LLMs) are increasingly applied to medicine, yet their adoption is limited by concerns over reliability and safety. Existing evaluations either test factual medical knowledge in isolation or assess patient-level…

Computation and Language · Computer Science 2026-05-08 Zhan Qu , Michael Färber

With the continuous evolution and refinement of LLMs, they are endowed with impressive logical reasoning or vertical thinking capabilities. But can they think out of the box? Do they possess proficient lateral thinking abilities? Following…

Computation and Language · Computer Science 2024-03-19 Shulin Huang , Shirong Ma , Yinghui Li , Mengzuo Huang , Wuhe Zou , Weidong Zhang , Hai-Tao Zheng

Large language models (LLMs) have achieved remarkable progress in code generation. However, existing benchmarks mainly formalize the task as a static, single-turn problem, overlooking the stepwise requirement changes and iterative workflows…

Software Engineering · Computer Science 2026-03-18 Zexun Zhan , Shuzheng Gao , Ruida Hu , Cuiyun Gao

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Medical question answering (QA) benchmarks often focus on multiple-choice or fact-based tasks, leaving open-ended answers to real patient questions underexplored. This gap is particularly critical in mental health, where patient questions…

Computation and Language · Computer Science 2026-05-15 Yahan Li , Jifan Yao , John Bosco S. Bunyi , Adam C. Frank , Angel Hsing-Chi Hwang , Ruishan Liu