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Robotic platforms provide consistent and precise tool positioning that significantly enhances retinal microsurgery. Integrating such systems with intraoperative optical coherence tomography (iOCT) enables image-guided robotic interventions,…

In the last decade, various robotic platforms have been introduced that could support delicate retinal surgeries. Concurrently, to provide semantic understanding of the surgical area, recent advances have enabled microscope-integrated…

Recent advancements in retinal surgery have paved the way for a modern operating room equipped with a surgical robot, a microscope, and intraoperative optical coherence tomography (iOCT)- a depth sensor widely used in retinal surgery.…

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

Purpose. Intraoperative Optical Coherence Tomography (iOCT) is an increasingly available imaging technique for ophthalmic microsurgery that provides high-resolution cross-sectional information of the surgical scene. We propose to build on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-20 Jakob Weiss , Nicola Rieke , Mohammad Ali Nasseri , Mathias Maier , Abouzar Eslami , Nassir Navab

Robotic ophthalmic surgery is an emerging technology to facilitate high-precision interventions such as retina penetration in subretinal injection and removal of floating tissues in retinal detachment depending on the input imaging…

Robotics · Computer Science 2023-11-16 Junjie Yang , Zhihao Zhao , Siyuan Shen , Daniel Zapp , Mathias Maier , Kai Huang , Nassir Navab , M. Ali Nasseri

Subretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as age-related macular degeneration (AMD). However, retinal motion caused by physiological factors such as respiration and…

Purpose: The integration of multimodal imaging into operating rooms paves the way for comprehensive surgical scene understanding. In ophthalmic surgery, by now, two complementary imaging modalities are available: operating microscope (OPMI)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Nikolo Rohrmoser , Ghazal Ghazaei , Michael Sommersperger , Nassir Navab

This paper presents an innovative approach to intraoperative Optical Coherence Tomography (iOCT) image segmentation in ophthalmic surgery, leveraging statistical analysis of speckle patterns to incorporate statistical pathology-specific…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Kristina Mach , Hessam Roodaki , Michael Sommersperger , Nassir Navab

Optical coherence tomography (OCT), a commonly used retinal imaging modality, plays a central role in retinal disease diagnosis by providing high-resolution visualization of retinal layers. While deep learning (DL) has achieved expert-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tienyu Chang , Tianhao Li , Ruogu Fang , Jiang Bian , Yu Huang

Intrinsic optical signal (IOS) imaging of the retina, also termed as optoretinography (ORG), promises a noninvasive method for objective assessment of retinal function. By providing unparalleled capability to differentiate individual layers…

Medical Physics · Physics 2022-02-22 Tae-Hoon Kim , Guangying Ma , Taeyoon Son , Xincheng Yao

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

Computer Vision and Pattern Recognition · Computer Science 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jiahong Ouyang , Tejas Sudharshan Mathai , Kira Lathrop , John Galeotti
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