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Scaling up quantum algorithms to tackle high-impact problems in science and industry requires quantum error correction and fault tolerance. While progress has been made in experimentally realizing error-corrected primitives, the end-to-end…

The Quantum Approximate Optimization Algorithm (QAOA) is a quantum-classical hybrid algorithm intending to find the ground state of a target Hamiltonian. Theoretically, QAOA can obtain the approximate solution if the quantum circuit is deep…

Quantum Physics · Physics 2022-04-26 Yahui Chai , Yong-Jian Han , Yu-Chun Wu , Ye Li , Menghan Dou , Guo-Ping Guo

Variational Quantum Algorithms (VQAs) provide a promising framework for tackling complex optimization problems on near-term quantum hardware. Here, we demonstrate that hybrid qubit--qumode quantum devices offer an efficient route to solving…

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

We present a method to split quantum circuits of variational quantum algorithms (VQAs) to allow for parallel training and execution, that maximally exploits the limited number of qubits in hardware to solve large problem instances. We apply…

Quantum Physics · Physics 2023-04-07 Michele Cattelan , Sheir Yarkoni

While quantum computers are a very promising tool for the far future, in their current state of the art they remain limited both in size and quality. This has given rise to hybrid quantum-classical algorithms, where the quantum device…

Quantum Physics · Physics 2026-01-26 Yury Chernyak , Ijaz Ahamed Mohammad , Martin Plesch

The increasing complexity and volume of financial transactions pose significant challenges to traditional fraud detection systems. This technical report investigates and compares the efficacy of classical, quantum, and quantum-hybrid…

Quantum Approximate Optimization Algorithm (QAOA) is one of the most promising quantum heuristics for combinatorial optimization. While QAOA has been shown to perform well on small-scale instances and to provide an asymptotic speedup over…

This paper proposes a generalized Hybrid Real-coded Quantum Evolutionary Algorithm (HRCQEA) for optimizing complex functions as well as combinatorial optimization. The main idea of HRCQEA is to devise a new technique for mutation and…

Neural and Evolutionary Computing · Computer Science 2013-03-07 Md. Amjad Hossain , Md. Kawser Hossain , M. M. A. Hashem

Federated Learning (FL) is a decentralized model training approach that preserves data privacy but struggles with low efficiency. Quantization, a powerful training optimization technique, has been widely explored for integration into FL.…

Machine Learning · Computer Science 2025-05-20 Zihao Zheng , Ziyao Wang , Xiuping Cui , Maoliang Li , Jiayu Chen , Yun , Liang , Ang Li , Xiang Chen

To enhance the variational quantum eigensolver (VQE), the CAFQA method can utilize classical computational capabilities to identify a better initial state than the Hartree-Fock method. Previous research has demonstrated that the initial…

Heterogeneous HPC workflow scheduling under multiple hard constraints poses a challenging combinatorial optimization problem. Classical exact solvers guarantee optimality but face scalability limits, motivating interest in quantum-inspired…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-26 Aasish Kumar Sharma , Christian Boehme , Julian Kunkel

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

Variational quantum approaches have shown great promise in finding near-optimal solutions to computationally challenging tasks. Nonetheless, enforcing constraints in a disciplined fashion has been largely unexplored. To address this gap,…

Quantum Physics · Physics 2024-04-30 Thinh Viet Le , Vassilis Kekatos

Variational quantum eigensolver (VQE) is demonstrated to be the promising methodology for quantum chemistry based on near-term quantum devices. However, many problems are yet to be investigated for this methodology, such as the influences…

Chemical Physics · Physics 2021-01-18 Xian-Hu Zha , Chao Zhang , Dengdong Fan , Pengxiang Xu , Shiyu Du , Rui-Qin Zhang , Chen Fu

Quantum computing brings a promise of new approaches into computational quantum chemistry. While universal, fault-tolerant quantum computers are still not available, we want to utilize today's noisy quantum processors. One of their flagship…

Fuzzing is widely used for detecting bugs and vulnerabilities, with various techniques proposed to enhance its effectiveness. To combine the advantages of multiple technologies, researchers proposed ensemble fuzzing, which integrates…

Software Engineering · Computer Science 2025-07-31 Yukai Zhao , Shaohua Wang , Jue Wang , Xing Hu , Xin Xia

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. This paper proposes hybrid models and methods that…

Quantum Physics · Physics 2019-11-12 Akshay Ajagekar , Travis Humble , Fengqi You

In the Noisy Intermediate Scale Quantum (NISQ) era, finding implementations of quantum algorithms that minimize the number of expensive and error prone multi-qubit gates is vital to ensure computations produce meaningful outputs. Unitary…

Quantum Physics · Physics 2023-06-12 Mathias Weiden , Ed Younis , Justin Kalloor , John Kubiatowicz , Costin Iancu

Efficiently solving large-scale sparse linear systems poses a significant challenge in computational science, especially in fields such as physics, engineering, machine learning, and finance. Traditional classical algorithms face…

Quantum Physics · Physics 2024-10-04 Hakikat Singh
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