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As a fundamental task in computational chemistry, retrosynthesis prediction aims to identify a set of reactants to synthesize a target molecule. Existing template-free approaches only consider the graph structures of the target molecule,…

Computation and Language · Computer Science 2024-01-29 Yifeng Liu , Hanwen Xu , Tangqi Fang , Haocheng Xi , Zixuan Liu , Sheng Zhang , Hoifung Poon , Sheng Wang

As Large Language Models (LLMs) become ubiquitous across various scientific domains, their lack of ability to perform complex tasks like running simulations or to make complex decisions limits their utility. LLM-based agents bridge this gap…

Computation and Language · Computer Science 2026-01-21 Anurag Acharya , Timothy Vega , Rizwan A. Ashraf , Anshu Sharma , Derek Parker , Robert Rallo

Dangerous radioactive waste leftover from the Cold War era nuclear weapons production continues to contaminate sixteen sites around the United States. Although many challenges and obstacles exist in decontaminating these sites, two…

Large reasoning models have demonstrated strong problem-solving abilities, yet real-world tasks often require external tools and long-horizon interactions. Existing agent frameworks typically follow predefined workflows, which limit…

Artificial Intelligence · Computer Science 2026-02-06 Xiaoxi Li , Wenxiang Jiao , Jiarui Jin , Guanting Dong , Jiajie Jin , Yinuo Wang , Hao Wang , Yutao Zhu , Ji-Rong Wen , Yuan Lu , Zhicheng Dou

Transition-metal compounds (TMCs) with open-shell d-electrons are characterized by a complex interplay of lattice, charge, orbital, and spin degrees of freedom, giving rise to a diverse range of fascinating applications. Often exhibiting…

Materials Science · Physics 2025-03-19 Yubo Zhang , Akilan Ramasamy , Kanun Pokharel , James W. Furness , Jinliang Ning , Ruiqi Zhang , Jianwei Sun

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

Optimization problems such as the NP-complete 3-SAT provide an important benchmark for the difficult task of finding ground-states in strongly correlated many-body systems with rugged energy landscapes. The study of random 3-SAT problems as…

Statistical Mechanics · Physics 2026-05-21 J. Schwardt , J. C. Budich

This paper addresses a generalization problem of Multi-Agent Pathfinding (MAPF), called Collaborative Task Sequencing - Multi-Agent Pathfinding (CTS-MAPF), where agents must plan collision-free paths and visit a series of intermediate task…

Robotics · Computer Science 2025-03-27 Junkai Jiang , Ruochen Li , Yibin Yang , Yihe Chen , Yuning Wang , Shaobing Xu , Jianqiang Wang

Advancements in theoretical and algorithmic approaches, workflow engines, and an ever-increasing computational power have enabled a novel paradigm for materials discovery through first-principles high-throughput simulations. A major…

Causal inference holds immense value in fields such as healthcare, economics, and social sciences. However, traditional causal analysis workflows impose significant technical barriers, requiring researchers to possess dual backgrounds in…

Artificial Intelligence · Computer Science 2026-02-13 Jiawei Zhu , Wei Chen , Ruichu Cai

Fast surrogate models for expensive simulations are now essential across the sciences, yet they typically operate as black boxes. We present \texttt{GWAgent}, a large language model (LLM)-based workflow that constructs interpretable…

General Relativity and Quantum Cosmology · Physics 2026-05-13 Tousif Islam , Digvijay Wadekar , Tejaswi Venumadhav , Matias Zaldarriaga , Ajit Kumar Mehta , Javier Roulet , Barak Zackay

Agentic Test-Time Scaling (TTS) has delivered state-of-the-art (SOTA) performance on complex software engineering tasks such as code generation and bug fixing. However, its practical adoption remains limited due to significant computational…

Software Engineering · Computer Science 2026-05-14 Chenhui Mao , Yuanting Lei , Zhixiang Wei , Ming Liang , Zhixiang Wang , Jingxuan Xu , Dajun Chen , Wei Jiang , Yong Li

Predicting the future behavior of moving agents is essential for real world applications. It is challenging as the intent of the agent and the corresponding behavior is unknown and intrinsically multimodal. Our key insight is that for…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Hang Zhao , Jiyang Gao , Tian Lan , Chen Sun , Benjamin Sapp , Balakrishnan Varadarajan , Yue Shen , Yi Shen , Yuning Chai , Cordelia Schmid , Congcong Li , Dragomir Anguelov

This paper proposes KC-TSS: K-Clustered-Traveling Salesman Based Search, a failure resilient path planning algorithm for heterogeneous robot teams performing target search in human environments. We separate the sample path generation…

Robotics · Computer Science 2022-03-03 Minkyu Kim , Ryan Gupta , Luis Sentis

The Boolean Satisfiability problem (SAT), as the prototypical $\mathsf{NP}$-complete problem, is crucial in both theoretical computer science and practical applications. To address this problem, stochastic local search (SLS) algorithms,…

Artificial Intelligence · Computer Science 2026-04-17 Maximilian J. Kramer , Paul Boes , Jens Eisert

Visual content and accompanied audio signals naturally formulate a joint representation to improve audio-visual (AV) related applications. While studies develop various AV representation learning frameworks, the importance of AV data…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Shentong Mo , Yibing Song

AI agents are increasingly used to solve complex, multi-step tasks, but existing multi-agent frameworks remain brittle as workflows grow in scale and depth. Small errors at intermediate stages can propagate through agent interactions, while…

Artificial Intelligence · Computer Science 2026-05-26 Andy Xu , Yu-Wing Tai

We present, to our knowledge, the first language-driven agent system capable of executing end-to-end collider phenomenology tasks, instantiated within a decoupled, domain-agnostic architecture for autonomous High-Energy Physics…

High Energy Physics - Phenomenology · Physics 2026-03-17 Shi Qiu , Zeyu Cai , Jiashen Wei , Zeyu Li , Yixuan Yin , Qing-Hong Cao , Chang Liu , Ming-xing Luo , Xing-Bo Yuan , Hua Xing Zhu

Existing Multi-Agent Systems (MAS) typically rely on homogeneous model configurations, failing to exploit the diverse expertise inherent in different post-trained architectures. We propose Team-of-Thoughts, a heterogeneous MAS framework…

Computation and Language · Computer Science 2026-03-26 Jeffrey T. H. Wong , Zixi Zhang , Junyi Liu , Yiren Zhao

In this article, we address the problem of collaborative task assignment, sequencing, and multi-agent pathfinding (TSPF), where a team of agents must visit a set of task locations without collisions while minimizing flowtime. TSPF…

Multiagent Systems · Computer Science 2025-10-28 Yifan Bai , Shruti Kotpalliwar , Christoforos Kanellakis , George Nikolakopoulos