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Predictive models may generate biased predictions when classifying imbalanced datasets. This happens when the model favors the majority class, leading to low performance in accurately predicting the minority class. To address this issue,…

Machine Learning · Computer Science 2026-05-18 Mustafa Cavus , Przemysław Biecek

Deep learning algorithms can fare poorly when the training dataset suffers from heavy class-imbalance but the testing criterion requires good generalization on less frequent classes. We design two novel methods to improve performance in…

Machine Learning · Computer Science 2019-10-29 Kaidi Cao , Colin Wei , Adrien Gaidon , Nikos Arechiga , Tengyu Ma

Imbalanced data poses a significant challenge in classification as model performance is affected by insufficient learning from minority classes. Balancing methods are often used to address this problem. However, such techniques can lead to…

Machine Learning · Computer Science 2024-06-18 Adrian Stando , Mustafa Cavus , Przemysław Biecek

We explore whether survival model performance in underrepresented high- and low-risk subgroups - regions of the prognostic spectrum where clinical decisions are most consequential - can be improved through targeted restructuring of the…

Accurate prediction and identification of variables associated with outcomes or disease states are critical for advancing diagnosis, prognosis, and precision medicine in biomedical research. Regularized regression techniques, such as lasso,…

Applications · Statistics 2025-04-14 Xiaoru Dong , Apoorva Goyal , Muxuan Liang , Maigan A. Brusko , Todd M. Brusko , Rhonda Bacher

Combining multiple modalities carrying complementary information through multimodal learning (MML) has shown considerable benefits for diagnosing multiple pathologies. However, the robustness of multimodal models to missing modalities is…

Machine Learning · Computer Science 2024-07-31 Hava Chaptoukaev , Vincenzo Marcianó , Francesco Galati , Maria A. Zuluaga

Biomedical research requires large, diverse samples to produce unbiased results. Automated methods for matching variables across datasets can accelerate this process. Research in this area has been limited, primarily focusing on lexical…

Computation and Language · Computer Science 2024-11-06 Zexu Li , Suraj P. Prabhu , Zachary T. Popp , Shubhi S. Jain , Vijetha Balakundi , Ting Fang Alvin Ang , Rhoda Au , Jinying Chen

Medical datasets are typically affected by issues such as missing values, class imbalance, a heterogeneous feature types, and a high number of features versus a relatively small number of samples, preventing machine learning models from…

Background: Large language models (LLMs) are increasingly proposed for diagnostic support, but few evaluations use real-world multimodal inpatient data, particularly in low and middle-income country (LMIC) public hospitals. Methods: We…

Objectives: Metabolic Bariatric Surgery (MBS) is a critical intervention for patients living with obesity and related health issues. Accurate classification and prediction of patient outcomes are vital for optimizing treatment strategies.…

Training deep learning models on medical datasets that perform well for all classes is a challenging task. It is often the case that a suboptimal performance is obtained on some classes due to the natural class imbalance issue that comes…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Atharv Savarkar , Venkat Iyer , Lakshman Tamil , Ganesh Ramakrishnan , Rishabh Iyer

In medical diagnostics, leveraging multiple biomarkers can significantly improve classification accuracy compared to using a single biomarker. While existing methods based on exponential tilting or density ratio models have shown promise,…

Methodology · Statistics 2026-01-08 Fangyong Zheng , Pengfei Li , Tao Yu

In biomedical and public health association studies, binary outcome variables may be subject to misclassification, resulting in substantial bias in effect estimates. The feasibility of addressing binary outcome misclassification in…

Methodology · Statistics 2024-03-19 Kimberly A. Hochstedler Webb , Martin T. Wells

Class imbalance exists in many classification problems, and since the data is designed for accuracy, imbalance in data classes can lead to classification challenges with a few classes having higher misclassification costs. The Backblaze…

Machine Learning · Computer Science 2023-10-16 Shuangshuang Yuan , Peng Wu , Yuehui Chen , Qiang Li

Developing an integrated many-to-many framework leveraging multimodal data for multiple tasks is crucial to unifying healthcare applications ranging from diagnoses to operations. In resource-constrained hospital environments, a scalable and…

Machine Learning · Computer Science 2024-06-11 Dimitris Bertsimas , Yu Ma

Class imbalance is a widespread challenge in NLP tasks, significantly hindering robust performance across diverse domains and applications. We introduce Hardness-Aware Meta-Resample (HAMR), a unified framework that adaptively addresses both…

Computation and Language · Computer Science 2026-04-22 Hanshu Rao , Guangzeng Han , Xiaolei Huang

Imbalanced Data (ID) is a problem that deters Machine Learning (ML) models for achieving satisfactory results. ID is the occurrence of a situation where the quantity of the samples belonging to one class outnumbers that of the other by a…

Although binary classification is a well-studied problem, training reliable classifiers under severe class imbalance remains a challenge. Recent techniques mitigate the ill effects of imbalance on training by modifying the loss functions or…

Machine Learning · Computer Science 2024-10-07 Kelsey Lieberman , Swarna Kamlam Ravindran , Shuai Yuan , Carlo Tomasi

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

Machine Learning · Statistics 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

Missing data represents a fundamental challenge in machine learning applications, often reducing model performance and reliability. This problem is particularly acute in fields like bioinformatics and clinical machine learning, where…

Machine Learning · Computer Science 2025-09-04 Fatemeh Azad , Zoran Bosnić , Matjaž Kukar