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Spatial Transcriptomics (ST) provides spatially resolved gene expression profiles within intact tissue architecture, enabling molecular analysis in histological context. However, the high cost, limited throughput, and restricted data…

Machine Learning · Computer Science 2026-03-31 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

UML and ER diagrams are foundational in computer science education but come with challenges for learners due to the need for abstract thinking, contextual understanding, and mastery of both syntax and semantics. These complexities are…

Human-Computer Interaction · Computer Science 2025-08-01 Sebastian Gürtl , Gloria Schimetta , David Kerschbaumer , Michael Liut , Alexander Steinmaurer

Device Model Generalization (DMG) is a practical yet under-investigated research topic for on-device machine learning applications. It aims to improve the generalization ability of pre-trained models when deployed on resource-constrained…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-03 Zheqi Lv , Wenqiao Zhang , Shengyu Zhang , Kun Kuang , Feng Wang , Yongwei Wang , Zhengyu Chen , Tao Shen , Hongxia Yang , Beng Chin Ooi , Fei Wu

Large language models (LLMs) have shown remarkable reasoning capabilities, yet aligning such abilities to small language models (SLMs) remains a challenge due to distributional mismatches and limited model capacity. Existing reasoning…

Computation and Language · Computer Science 2025-05-28 Yong Wu , Weihang Pan , Ke Li , Chen Binhui , Ping Li , Binbin Lin

Following language instructions to navigate in unseen environments is a challenging problem for autonomous embodied agents. The agent not only needs to ground languages in visual scenes, but also should explore the environment to reach its…

Computer Vision and Pattern Recognition · Computer Science 2022-02-25 Shizhe Chen , Pierre-Louis Guhur , Makarand Tapaswi , Cordelia Schmid , Ivan Laptev

Computer Vision has proven to be a powerful tool for analyzing Spatial Transcriptomics (ST) data. However, current models that predict spatially resolved gene expression from histopathology images suffer from significant limitations due to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Paula Cárdenas , Leonardo Manrique , Daniela Vega , Daniela Ruiz , Pablo Arbeláez

The rapid advancement of deep learning models often attributes to their ability to leverage massive training data. In contrast, such privilege has not yet fully benefited 3D deep learning, mainly due to the limited availability of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Xiaoyang Wu , Zhuotao Tian , Xin Wen , Bohao Peng , Xihui Liu , Kaicheng Yu , Hengshuang Zhao

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Spatial Transcriptomics (ST) reveals the spatial distribution of gene expression in tissues, offering critical insights into biological processes and disease mechanisms. However, the high cost, limited coverage, and technical complexity of…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Yi Niu , Jiashuai Liu , Yingkang Zhan , Jiangbo Shi , Di Zhang , Marika Reinius , Ines Machado , Mireia Crispin-Ortuzar , Jialun Wu , Chen Li , Zeyu Gao

We tackle the challenge of detecting multiple change points in large time series by optimising a penalised likelihood derived from exponential family models. Dynamic programming algorithms can solve this task exactly with at most quadratic…

Methodology · Statistics 2025-07-14 Vincent Runge , Charles Truong , Simon Querné

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez

Using synthetic data for training neural networks that achieve good performance on real-world data is an important task as it can reduce the need for costly data annotation. Yet, synthetic and real world data have a domain gap. Reducing…

Computer Vision and Pattern Recognition · Computer Science 2022-08-12 Shahaf Ettedgui , Shady Abu-Hussein , Raja Giryes

Domain adaptation for semantic segmentation aims to improve the model performance in the presence of a distribution shift between source and target domain. Leveraging the supervision from auxiliary tasks~(such as depth estimation) has the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Qin Wang , Dengxin Dai , Lukas Hoyer , Luc Van Gool , Olga Fink

Prior works have proposed several strategies to reduce the computational cost of self-attention mechanism. Many of these works consider decomposing the self-attention procedure into regional and local feature extraction procedures that each…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Ting Yao , Yehao Li , Yingwei Pan , Yu Wang , Xiao-Ping Zhang , Tao Mei

This paper introduces Dynamic Embeddings with Task-Oriented prompting (DETOT), a novel approach aimed at improving the adaptability and efficiency of machine learning models by implementing a flexible embedding layer. Unlike traditional…

Computation and Language · Computer Science 2024-06-25 Allmin Balloccu , Jack Zhang

Learning effective region embeddings from heterogeneous urban data underpins key urban computing tasks (e.g., crime prediction, resource allocation). However, prevailing two-stage methods yield task-agnostic representations, decoupling them…

Artificial Intelligence · Computer Science 2026-02-03 Zitao Guo , Changyang Jiang , Tianhong Zhao , Jinzhou Cao , Genan Dai , Bowen Zhang

Accurate monocular 3D object detection (M3OD) is pivotal for safety-critical applications like autonomous driving, yet its reliability deteriorates significantly under real-world domain shifts caused by environmental or sensor variations.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Zixuan Hu , Dongxiao Li , Xinzhu Ma , Shixiang Tang , Xiaotong Li , Wenhan Yang , Ling-Yu Duan

Accurate segmentation of brain tissues from MRI scans is critical for neuroscience and clinical applications, but achieving consistent performance across the human lifespan remains challenging due to dynamic, age-related changes in brain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yongheng Sun , Jun Shu , Jianhua Ma , Fan Wang

The accuracy of deep learning (e.g., convolutional neural networks) for an image classification task critically relies on the amount of labeled training data. Aiming to solve an image classification task on a new domain that lacks labeled…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Xianghong Fang , Haoli Bai , Ziyi Guo , Bin Shen , Steven Hoi , Zenglin Xu

Spatially resolved transcriptomics (SRT) has evolved rapidly through various technologies, enabling scientists to investigate both morphological contexts and gene expression profiling at single-cell resolution in parallel. SRT data are…