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Multi-agent systems built on large language models (LLMs) require many coordination choices that are difficult to fix a priori: which skill protocol to invoke, which agent role should perform a subtask, which model to bind to each role, how…

Multiagent Systems · Computer Science 2026-05-28 Nicole Koenigstein

Autonomous agentic workflows that iteratively refine their own behavior hold considerable promise, yet their failure modes remain poorly characterized. We investigate optimization instability, a phenomenon in which continued autonomous…

Artificial Intelligence · Computer Science 2026-02-19 Cameron Cagan , Pedram Fard , Jiazi Tian , Jingya Cheng , Shawn N. Murphy , Hossein Estiri

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Agentic workflows in large language model systems integrate retrieval, reasoning, and memory, but existing frameworks suffer from scalability and reproducibility limitations due to fragmented data orchestration, serialization overhead, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-05 Arup Kumar Sarker , Mills Staylor , Aymen Alsaadi , Gregor von Laszewski , Shantenu Jha , Geoffrey Fox

Despite the remarkable progress of large language models (LLMs), the capabilities of standalone LLMs have begun to plateau when tackling real-world, complex tasks that require interaction with external tools and dynamic environments.…

Recent advances in Large Vision-Language Models (LVLMs) have shown strong potential for multi-modal radiological reasoning, particularly in tasks like diagnostic visual question answering (VQA) and radiology report generation. However, most…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yannian Gu , Xizhuo Zhang , Linjie Mu , Yongrui Yu , Zhongzhen Huang , Shaoting Zhang , Xiaofan Zhang

Modern language agents must operate over long-horizon, multi-turn histories, yet deploying such agents with Small Language Models (SLMs) remains fundamentally difficult. Full-context prompting causes context overflow, flat retrieval exposes…

Multiagent Systems · Computer Science 2026-05-06 Jiayi Chen , Yingcong Li , Guiling Wang

In recent years, a variety of powerful LLM-based agentic systems have been applied to automate complex tasks through task orchestration. However, existing orchestration methods still face key challenges, including strategy collapse under…

Artificial Intelligence · Computer Science 2026-05-15 Mingda Zhang , Tiesunlong Shen , Haoran Luo , Wenjin Liu , Zikai Xiao , Erik Cambria , Xiaoying Tang

The application of Large Language Models (LLMs) in healthcare is expanding rapidly, with one potential use case being the translation of formal medical reports into patient-legible equivalents. Currently, LLM outputs often need to be edited…

Multiagent Systems · Computer Science 2024-08-06 Malavikha Sudarshan , Sophie Shih , Estella Yee , Alina Yang , John Zou , Cathy Chen , Quan Zhou , Leon Chen , Chinmay Singhal , George Shih

We present Verified Multi-Agent Orchestration (VMAO), a framework that coordinates specialized LLM-based agents through a verification-driven iterative loop. Given a complex query, our system decomposes it into a directed acyclic graph…

Artificial Intelligence · Computer Science 2026-03-17 Xing Zhang , Yanwei Cui , Guanghui Wang , Wei Qiu , Ziyuan Li , Fangwei Han , Yajing Huang , Hengzhi Qiu , Bing Zhu , Peiyang He

Purpose: The purpose of this study was to determine if an ensemble of multiple LLM agents could be used collectively to provide a more reliable assessment of a pixel-based AI triage tool than a single LLM. Methods: 29,766 non-contrast CT…

Computation and Language · Computer Science 2025-10-31 Adam E. Flanders , Yifan Peng , Luciano Prevedello , Robyn Ball , Errol Colak , Prahlad Menon , George Shih , Hui-Ming Lin , Paras Lakhani

GraphFlow is a visual workflow system designed to improve the reliability of agentic AI automation in multi-step, mission-critical processes. In these workflows, small errors compound rapidly: under an idealized model of independent steps,…

Artificial Intelligence · Computer Science 2026-05-15 Drewry H. Morris , Luis Valles , Reza Hosseini Ghomi

The rapidly growing demand for high-quality data in Large Language Models (LLMs) has intensified the need for scalable, reliable, and semantically rich data preparation pipelines. However, current practices remain dominated by ad-hoc…

Many tool-based Retrieval Augmented Generation (RAG) systems lack precise mechanisms for tracing final responses back to specific tool components -- a critical gap as systems scale to complex multi-agent architectures. We present…

Information Retrieval · Computer Science 2026-02-06 James Gao , Josh Zhou , Qi Sun , Ryan Huang , Steven Yoo

LLM agents have begun to find real security vulnerabilities that human auditors and automated fuzzers missed for decades, in source-available targets where the analyst can build and instrument the code. In practice the work is split among…

Cryptography and Security · Computer Science 2026-04-23 Hanzhi Liu , Chaofan Shou , Xiaonan Liu , Hongbo Wen , Yanju Chen , Ryan Jingyang Fang , Yu Feng

The efficacy of AI agents in healthcare research is hindered by their reliance on static, predefined strategies. This creates a critical limitation: agents can become better tool-users but cannot learn to become better strategic planners, a…

Artificial Intelligence · Computer Science 2025-08-08 Huiya Zhao , Yinghao Zhu , Zixiang Wang , Yasha Wang , Junyi Gao , Liantao Ma

Reasoning over heterogeneous artifacts (PDFs, spreadsheets, slide decks, etc.) increasingly occurs within structured agent workflows that iteratively extract, transform, and reference external information. In these workflows, uncertainty is…

Artificial Intelligence · Computer Science 2026-05-01 Anna Mazhar , Huzaifa Suri , Sainyam Galhotra

Automated evaluation of tool-using large language model (LLM) agents is widely assumed to be reliable, but this assumption has rarely been validated against human annotation. We introduce AgentProp-Bench, a 2,000-task benchmark with 2,300…

Artificial Intelligence · Computer Science 2026-04-21 Bhaskar Gurram

Power grid fault diagnosis is a critical process hindered by its reliance on manual, error-prone methods. Technicians must manually extract reasoning logic from dense regulations and attempt to combine it with tacit expert knowledge, which…

Artificial Intelligence · Computer Science 2025-11-18 Yafang Wang , Yangjie Tian , Xiaoyu Shen , Gaoyang Zhang , Jiaze Sun , He Zhang , Ruohua Xu , Feng Zhao

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud
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