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Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

Survival prediction is a crucial task in the medical field and is essential for optimizing treatment options and resource allocation. However, current methods often rely on limited data modalities, resulting in suboptimal performance. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Binyu Zhang , Zhu Meng , Junhao Dong , Fei Su , Zhicheng Zhao

Technological advances in medical data collection, such as high-throughput genomic sequencing and digital high-resolution histopathology, have contributed to the rising requirement for multimodal biomedical modelling, specifically for…

Machine Learning · Computer Science 2024-10-29 Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Multimodal fusion frameworks, which integrate diverse medical imaging modalities (e.g., MRI, CT), have shown great potential in applications such as skin cancer detection, dementia diagnosis, and brain tumor prediction. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 J. Dhar , M. K. Pandey , D. Chakladar , M. Haghighat , A. Alavi , S. Mistry , N. Zaidi

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

The integration of pathologic images and genomic data for survival analysis has gained increasing attention with advances in multimodal learning. However, current methods often ignore biological characteristics, such as heterogeneity and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Shuaiyu Zhang , Xun Lin , Rongxiang Zhang , Yu Bai , Yong Xu , Tao Tan , Xunbin Zheng , Zitong Yu

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Survival prediction is a critical task in pathology. In clinical practice, pathologists often examine multiple cases, leveraging a broader spectrum of cancer phenotypes to enhance pathological assessment. Despite significant advancements in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Xinyang Li , Yi Zhang , Yi Xie , Jianfei Yang , Xi Wang , Hao Chen , Haixian Zhang

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi
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