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Decomposing prediction uncertainty into aleatoric (irreducible) and epistemic (reducible) components is critical for the reliable deployment of machine learning systems. While the mutual information between the response variable and model…

Machine Learning · Statistics 2026-02-10 Anchit Jain , Stephen Bates

The requirement of uncertainty quantification for anomaly detection systems has become increasingly important. In this context, effectively controlling Type I error rates ($\alpha$) without compromising the statistical power ($1-\beta$) of…

Machine Learning · Statistics 2025-02-21 Oliver Hennhöfer , Christine Preisach

Quantifying the data uncertainty in learning tasks is often done by learning a prediction interval or prediction set of the label given the input. Two commonly desired properties for learned prediction sets are \emph{valid coverage} and…

Machine Learning · Computer Science 2022-05-31 Yu Bai , Song Mei , Huan Wang , Yingbo Zhou , Caiming Xiong

We present an efficient approach for generating highly accurate molecular potential energy surfaces (PESs) using self-correcting, kernel ridge regression (KRR) based machine learning (ML). We introduce structure-based sampling to…

Chemical Physics · Physics 2018-08-20 Pavlo O. Dral , Alec Owens , Sergei N. Yurchenko , Walter Thiel

Uncertainty quantification is essential for deploying machine learning models in high-stakes domains such as scientific discovery and healthcare. Conformal Prediction (CP) provides finite-sample coverage guarantees under exchangeability, an…

Machine Learning · Computer Science 2026-03-30 Siddhartha Laghuvarapu , Rohan Deb , Jimeng Sun

In a \emph{data poisoning attack}, an attacker modifies, deletes, and/or inserts some training examples to corrupt the learnt machine learning model. \emph{Bootstrap Aggregating (bagging)} is a well-known ensemble learning method, which…

Cryptography and Security · Computer Science 2020-12-11 Jinyuan Jia , Xiaoyu Cao , Neil Zhenqiang Gong

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Assisted by the availability of data and high performance computing, deep learning techniques have achieved breakthroughs and surpassed human performance empirically in difficult tasks, including object recognition, speech recognition, and…

Machine Learning · Computer Science 2019-01-23 Shaeke Salman , Xiuwen Liu

The estimated accuracy of a classifier is a random quantity with variability. A common practice in supervised machine learning, is thus to test if the estimated accuracy is significantly better than chance level. This method of signal…

Methodology · Statistics 2020-01-28 Jonathan D. Rosenblatt , Yuval Benjamini , Roee Gilron , Roy Mukamel , Jelle J. Goeman

Bias correction can often improve the finite sample performance of estimators. We show that the choice of bias correction method has no effect on the higher-order variance of semiparametrically efficient parametric estimators, so long as…

Econometrics · Economics 2024-01-29 Jinyong Hahn , David W. Hughes , Guido Kuersteiner , Whitney K. Newey

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Machine learning theory has mostly focused on generalization to samples from the same distribution as the training data. Whereas a better understanding of generalization beyond the training distribution where the observed distribution…

Machine Learning · Statistics 2019-05-29 Matias Vera , Pablo Piantanida , Leonardo Rey Vega

Daily streamflow forecasting through data-driven approaches is traditionally performed using a single machine learning algorithm. Existing applications are mostly restricted to examination of few case studies, not allowing accurate…

Machine Learning · Statistics 2021-03-24 Hristos Tyralis , Georgia Papacharalampous , Andreas Langousis

Certifying whether an arbitrary quantum system is entangled or not, is, in general, an NP-hard problem. Though various necessary and sufficient conditions have already been explored in this regard for lower dimensional systems, it is hard…

Quantum Physics · Physics 2024-12-03 Sanuja D. Mohanty , Ram N. Patro , Pradyut K. Biswal , Biswajit Pradhan , Sk Sazim

We investigate the impact of choosing regressors and molecular representations for the construction of fast machine learning (ML) models of thirteen electronic ground-state properties of organic molecules. The performance of each…

The method introduced in this paper aims at helping deep learning practitioners faced with an overfit problem. The idea is to replace, in a multi-branch network, the standard summation of parallel branches with a stochastic affine…

Machine Learning · Computer Science 2017-05-24 Xavier Gastaldi

Engineering simulators used for steady-state multiphase pipe flows are commonly utilized to predict pressure drop. Such simulators are typically based on either empirical correlations or first-principles mechanistic models. The simulators…

Data Analysis, Statistics and Probability · Physics 2019-06-04 Evgenii Kanin , Andrei Osiptsov , Albert Vainshtein , Evgeny Burnaev

Machine learning methods tend to outperform traditional statistical models at prediction. In the prediction of academic achievement, ML models have not shown substantial improvement over logistic regression. So far, these results have…

Machine Learning · Statistics 2020-04-21 Sarah Cornell-Farrow , Robert Garrard

Recently, artificial intelligence technologies and algorithms have become a major focus for advancements in treatment planning for radiation therapy. As these are starting to become incorporated into the clinical workflow, a major concern…

Purpose: Despite the potential of machine learning models, the lack of generalizability has hindered their widespread adoption in clinical practice. We investigate three methodological pitfalls: (1) violation of independence assumption, (2)…

Machine Learning · Computer Science 2022-09-09 Farhad Maleki , Katie Ovens , Rajiv Gupta , Caroline Reinhold , Alan Spatz , Reza Forghani
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