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Image fusion is a fundamental and important task in computer vision, aiming to combine complementary information from different modalities to fuse images. In recent years, diffusion models have made significant developments in the field of…

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Reaction-diffusion (RD) equations underpin pattern formation across chemistry, biology, and physics, yet learning stable operators that forecast their long-term dynamics from data remains challenging. Neural-operator surrogates provide…

Machine Learning · Computer Science 2026-02-11 Huseyin Tunc

High-level autonomous driving requires motion planners capable of modeling multimodal future uncertainties while remaining robust in closed-loop interactions. Although diffusion-based planners are effective at modeling complex trajectory…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Hao Gao , Shaoyu Chen , Yifan Zhu , Yuehao Song , Wenyu Liu , Qian Zhang , Xinggang Wang

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

Radiotherapy is used to treat cancer patients by damaging DNA of tumor cells using ionizing radiation. Photons are the most widely used radiation type for therapy, having been put into use soon after the first discovery of X-rays in 1895.…

Optimization and Control · Mathematics 2019-11-20 Roman Levin , Aleksandr Y. Aravkin , Minsun Kim

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Reinforcement learning (RL)-based fine-tuning has emerged as a powerful approach for aligning diffusion models with black-box objectives. Proximal policy optimization (PPO) is a popular choice of method for policy optimization. While…

Representing and quantifying Minimal Residual Disease (MRD) in Acute Myeloid Leukemia (AML), a type of cancer that affects the blood and bone marrow, is essential in the prognosis and follow-up of AML patients. As traditional cytological…

Multi-modal images play a crucial role in comprehensive evaluations in medical image analysis providing complementary information for identifying clinically important biomarkers. However, in clinical practice, acquiring multiple modalities…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

Abdominal organ and tumour segmentation has many important clinical applications, such as organ quantification, surgical planning, and disease diagnosis. However, manual assessment is inherently subjective with considerable inter- and…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Wentao Liu , Tong Tian , Weijin Xu , Lemeng Wang , Haoyuan Li , Huihua Yang

Accurately identifying oocytes that progress to the blastocyst stage is crucial in reproductive medicine, but the limited availability of annotated high-quality embryo images presents challenges for developing automated diagnostic tools. To…

Quantitative Methods · Quantitative Biology 2025-06-18 Alejandro Golfe , Natalia P. García-de-la-puente , Adrián Colomer , Valery Naranjo

Reinforcement learning (RL) has shown extraordinary potential in aligning diffusion models to downstream tasks, yet most of them still suffer from significant reward hacking, which degrades generative diversity and quality by inducing…

Machine Learning · Computer Science 2026-05-14 Jiaming Li , Chenyu Zhu , Nanxi Yi , Youjun Bao , Li Sun , Quanying Lv , Xiang Fang , Daizong Liu , Jianjun Li , Kun He , Bowen Zhou , Zhiyuan Ma

Mastering dexterous robotic manipulation of deformable objects is vital for overcoming the limitations of parallel grippers in real-world applications. Current trajectory optimisation approaches often struggle to solve such tasks due to the…

Robotics · Computer Science 2024-03-20 Jun Yamada , Shaohong Zhong , Jack Collins , Ingmar Posner

Matrix-based optimizers have attracted growing interest for improving LLM training efficiency, with significant progress centered on orthogonalization/whitening based methods. While yielding substantial performance gains, a fundamental…

Machine Learning · Computer Science 2026-02-10 Wenbo Gong , Javier Zazo , Qijun Luo , Puqian Wang , James Hensman , Chao Ma

Diffusion models are a class of flexible generative models trained with an approximation to the log-likelihood objective. However, most use cases of diffusion models are not concerned with likelihoods, but instead with downstream objectives…

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We introduce the Approximated Optimal Transport (AOT) technique, a novel training scheme for diffusion-based generative models. Our approach aims to approximate and integrate optimal transport into the training process, significantly…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Daegyu Kim , Jooyoung Choi , Chaehun Shin , Uiwon Hwang , Sungroh Yoon

Leveraging the powerful capabilities of diffusion models has yielded quite effective results in medical image segmentation tasks. However, existing methods typically transfer the original training process directly without specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Qilin Huang , Tianyu Lin , Zhiguang Chen , Fudan Zheng

We present Diffusion-KTO, a novel approach for aligning text-to-image diffusion models by formulating the alignment objective as the maximization of expected human utility. Since this objective applies to each generation independently,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shufan Li , Konstantinos Kallidromitis , Akash Gokul , Yusuke Kato , Kazuki Kozuka

With the rapid advances in diffusion models, generating decent images from text prompts is no longer challenging. The key to text-to-image generation is how to optimize the results of a text-to-image generation model so that they can be…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Xiwen Wang , Jizhe Zhou , Xuekang Zhu , Cheng Li , Mao Li

Diffusion models have demonstrated exceptional capabilities in generating high-fidelity images. However, their iterative denoising process results in significant computational overhead during inference, limiting their practical deployment…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Xiaomeng Yang , Lei Lu , Qihui Fan , Changdi Yang , Juyi Lin , Yanzhi Wang , Xuan Zhang , Shangqian Gao