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The dose delivered to the planning target volume by proton beams is highly conformal, sparing organs at risk and normal tissues. New treatment planning systems adapted to spot scanning techniques have been recently proposed to…

Medical Physics · Physics 2022-05-18 François Smekens , Nicolas Freud , Bruno Sixou , Guillaume Beslon , Jean M Létang

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Diffusion models have emerged as powerful tools for 3D medical image generation, yet bridging the gap between standard training objectives and clinical relevance remains a challenge. This paper presents a method to enhance 3D diffusion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yueying Tian , Xudong Han , Meng Zhou , Rodrigo Aviles-Espinosa , Rupert Young , Philip Birch

Diffusion-based planners have emerged as a promising approach for human-like trajectory generation in autonomous driving. Recent works incorporate reinforcement fine-tuning to enhance the robustness of diffusion planners through…

Learning to Optimize (L2O) enhances optimization efficiency with integrated neural networks. L2O paradigms achieve great outcomes, e.g., refitting optimizer, generating unseen solutions iteratively or directly. However, conventional L2O…

Machine Learning · Computer Science 2025-03-17 Mingjia Shi , Ruihan Lin , Xuxi Chen , Yuhao Zhou , Zezhen Ding , Pingzhi Li , Tong Wang , Kai Wang , Zhangyang Wang , Jiheng Zhang , Tianlong Chen

Fluence map prediction is central to automated radiotherapy planning but remains an ill-posed inverse problem due to the complex relationship between volumetric anatomy and beam-intensity modulation. Convolutional methods in prior work…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Ujunwa Mgboh , Rafi Ibn Sultan , Joshua Kim , Kundan Thind , Dongxiao Zhu

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

Flow and diffusion models have demonstrated strong performance and training stability across various tasks but lack two critical properties of simulation-based methods: freedom of dimensionality and adaptability to different inference…

Machine Learning · Computer Science 2025-08-13 Dohoon Lee , Jaehyun Park , Hyunwoo J. Kim , Kyogu Lee

Recent progress in imitation learning has been enabled by policy architectures that scale to complex visuomotor tasks, multimodal distributions, and large datasets. However, these methods often rely on learning from large amount of expert…

Robotics · Computer Science 2025-04-24 Amber Xie , Oleh Rybkin , Dorsa Sadigh , Chelsea Finn

Gasoline blending scheduling uses resource allocation and operation sequencing to meet a refinery's production requirements. The presence of nonlinearity, integer constraints, and a large number of decision variables adds complexity to this…

Artificial Intelligence · Computer Science 2024-02-23 Wenxuan Fang , Wei Du , Renchu He , Yang Tang , Yaochu Jin , Gary G. Yen

We introduce a new algorithm to solve a regularized spatial-spectral image estimation problem. Our approach is based on the linearized alternating directions method of multipliers (LADMM), which is a variation of the popular ADMM algorithm.…

Signal Processing · Electrical Eng. & Systems 2025-02-25 Yunsong Liu , Debdut Mandal , Congyu Liao , Kawin Setsompop , Justin P. Haldar

This paper proposes latent visualization by optimization (LVO), a mechanistic interpretability technique that extends feature visualization by optimization - originally developed for convolutional neural networks - to latent diffusion…

Machine Learning · Computer Science 2026-05-12 Adam Szokalski , Mateusz Modrzejewski

Diffusion models have demonstrated strong capabilities for modeling human-like driving behaviors in autonomous driving, but their iterative sampling process induces substantial latency, and operating directly on raw trajectory points forces…

Robotics · Computer Science 2026-03-06 Jinhao Zhang , Wenlong Xia , Zhexuan Zhou , Haoming Song , Youmin Gong , Jie Mei

Diffusion- and flow-based models have emerged as state-of-the-art generative modeling approaches, but they require many sampling steps. Consistency models can distill these models into efficient one-step generators; however, unlike flow-…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Amirmojtaba Sabour , Sanja Fidler , Karsten Kreis

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…

Diffusion models are widely used for generative tasks across domains. Given a pre-trained diffusion model, it is often desirable to fine-tune it further either to correct for errors in learning or to align with downstream applications.…

We introduce Lavender, a simple supervised fine-tuning (SFT) method that boosts the performance of advanced vision-language models (VLMs) by leveraging state-of-the-art image generation models such as Stable Diffusion. Specifically,…

Machine Learning · Computer Science 2025-05-27 Chen Jin , Ryutaro Tanno , Amrutha Saseendran , Tom Diethe , Philip Teare

Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang

Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high doses to tumor regions while sparing surrounding tissues. Traditional LATTICE uses rigid vertex patterns, limiting…

Medical Physics · Physics 2025-05-21 Xin Tong , Weijie Zhang , Ya-Nan Zhu , Xue Hong , Chao Wang , Jufri Setianegara , Yuting Lin , Hao Gao

Predict-then-Optimize (PTO) pipelines are widely employed in computing and networked systems, where Machine Learning (ML) models are used to predict critical contextual information for downstream decision-making tasks such as cloud LLM…

Machine Learning · Computer Science 2026-02-04 Jiaqi Wen , Lei Fan , Jianyi Yang