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The inherent multimodality and heterogeneous temporal structures of medical data pose significant challenges for modeling. We propose MedM2T, a time-aware multimodal framework designed to address these complexities. MedM2T integrates: (i)…

Machine Learning · Computer Science 2026-03-26 Yu-Chen Kuo , Yi-Ju Tseng

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

The proliferation of edge devices has generated an unprecedented volume of time series data across different domains, motivating various well-customized methods. Recently, Large Language Models (LLMs) have emerged as a new paradigm for time…

Machine Learning · Computer Science 2025-05-06 Chenxi Liu , Shaowen Zhou , Qianxiong Xu , Hao Miao , Cheng Long , Ziyue Li , Rui Zhao

Multimodal recommender systems (MRS) integrate heterogeneous user and item data, such as text, images, and structured information, to enhance recommendation performance. The emergence of large language models (LLMs) introduces new…

Information Retrieval · Computer Science 2025-05-16 Alejo Lopez-Avila , Jinhua Du

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

Electronic health records (EHRs) contain structured and unstructured data of significant clinical and research value. Various machine learning approaches have been developed to employ information in EHRs for risk prediction. The majority of…

Effective analysis of time series data presents significant challenges due to the complex temporal dependencies and cross-channel interactions in multivariate data. Inspired by the way human analysts visually inspect time series to uncover…

Machine Learning · Computer Science 2025-10-10 Qinghua Liu , Sam Heshmati , Zheda Mai , Zubin Abraham , John Paparrizos , Liu Ren

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

To address the modality imbalance caused by data heterogeneity, existing multi-modal learning (MML) approaches primarily focus on balancing this difference from the perspective of optimization objectives. However, almost all existing…

Machine Learning · Computer Science 2025-01-06 Zhi-Hao Guan

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Missing values, irregularly collected samples, and multi-resolution signals commonly occur in multivariate time series data, making predictive tasks difficult. These challenges are especially prevalent in the healthcare domain, where…

Multimodal Entity Linking (MEL) is a fundamental task in data management that maps ambiguous mentions with diverse modalities to the multimodal entities in a knowledge base. However, most existing MEL approaches primarily focus on…

Computation and Language · Computer Science 2026-04-23 Mo Zhou , Jianwei Wang , Kai Wang , Helen Paik , Ying Zhang , Wenjie Zhang

Large language models (LLMs) can generate fluent clinical summaries of remote therapeutic monitoring time series. However, it remains unclear whether these narratives faithfully capture clinically significant events, such as sustained…

Artificial Intelligence · Computer Science 2026-03-03 Aditya Shukla , Yining Yuan , Ben Tamo , Yifei Wang , Micky Nnamdi , Shaun Tan , Jieru Li , Benoit Marteau , Brad Willingham , May Wang

Multimodal large language models (MLLMs) enhance the capabilities of standard large language models by integrating and processing data from multiple modalities, including text, vision, audio, video, and 3D environments. Data plays a pivotal…

Artificial Intelligence · Computer Science 2024-07-19 Tianyi Bai , Hao Liang , Binwang Wan , Yanran Xu , Xi Li , Shiyu Li , Ling Yang , Bozhou Li , Yifan Wang , Bin Cui , Ping Huang , Jiulong Shan , Conghui He , Binhang Yuan , Wentao Zhang

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Reconstructing precise clinical timelines is essential for modeling patient trajectories and forecasting risk in complex, heterogeneous conditions like sepsis. While unstructured clinical narratives offer semantically rich and contextually…

Computation and Language · Computer Science 2026-05-15 Sayantan Kumar , Shahriar Noroozizadeh , Juyong Kim , Jeremy C. Weiss

Large Language Models (LLMs) have demonstrated impressive performance in time series analysis and seems to understand the time temporal relationship well than traditional transformer-based approaches. However, since LLMs are not designed…

Machine Learning · Computer Science 2025-05-27 Liangwei Nathan Zheng , Chang George Dong , Wei Emma Zhang , Lin Yue , Miao Xu , Olaf Maennel , Weitong Chen

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with…

Machine Learning · Computer Science 2023-06-07 Xinlu Zhang , Shiyang Li , Zhiyu Chen , Xifeng Yan , Linda Petzold

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

Machine Learning · Computer Science 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

Large-scale EHR prediction across institutions is hindered by substantial heterogeneity in schemas and code systems. Although Common Data Models (CDMs) can standardize records for multi-institutional learning, the manual harmonization and…

Computation and Language · Computer Science 2026-04-02 Kyunghoon Hur , Heeyoung Kwak , Jinsu Jang , Nakhwan Kim , Edward Choi