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Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

Populations and Evolution · Quantitative Biology 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

A new approach for generating stress-constrained topological designs in continua is presented. The main novelty is in the use of elasto-plastic modeling and in optimizing the design such that it will exhibit a linear-elastic response. This…

Computational Engineering, Finance, and Science · Computer Science 2016-08-25 Oded Amir

We study the equilibrium configurations related to the growth of an elastic fibre in a confining flexible ring. This system represents a paradigm for a variety of biological, medical, and engineering problems. We consider a simplified…

Soft Condensed Matter · Physics 2022-10-17 Arsenio Cutolo , Massimiliano Fraldi , Gaetano Napoli , Giuseppe Puglisi

While evolutionary algorithms are known to be very successful for a broad range of applications, the algorithm designer is often left with many algorithmic choices, for example, the size of the population, the mutation rates, and the…

Neural and Evolutionary Computing · Computer Science 2015-04-14 Benjamin Doerr , Carola Doerr

We examine the conjectured asymptotic shape of the three dimensional corner growth model [Olejarz et. al.,PRL, 108, 016102 (2012)] by mapping the model onto a restricted solid on solid model on a triangular lattice. By choosing appropriate…

Statistical Mechanics · Physics 2015-06-12 Rajeev Singh , R. Rajesh

We study a class of convex-concave min-max problems in which the coupled component of the objective is linear in at least one of the two decision vectors. We identify such problem structure as interpolating between the bilinearly and…

Optimization and Control · Mathematics 2025-07-10 Ronak Mehta , Jelena Diakonikolas , Zaid Harchaoui

We consider the problem of optimization of cost functionals on the infinite-dimensional manifold of diffeomorphisms. We present a new class of optimization methods, valid for any optimization problem setup on the space of diffeomorphisms by…

Optimization and Control · Mathematics 2018-05-25 Ganesh Sundaramoorthi , Anthony Yezzi

This paper concerns the asymptotic behaviour of solutions of a linear convolution Volterra summation equation with an unbounded forcing term. In particular, we suppose the kernel is summable and ascribe growth bounds to the exogenous…

Dynamical Systems · Mathematics 2019-08-07 John A. D. Appleby , Denis D. Patterson

We focus on establishing the foundational paradigm of a novel optimization theory based on convolution with convex kernels. Our goal is to devise a morally deterministic model of locating the global optima of an arbitrary function, which is…

Optimization and Control · Mathematics 2025-03-31 Zhipeng Lu

The transient growth of disturbances made possible by the non-normality of the linearized Navier-Stokes equations plays an important role in bypass transition for many shear flows. Transient growth is typically quantified by the maximum…

Fluid Dynamics · Physics 2026-03-24 Zhicheng Kai , Peter Frame , Aaron Towne

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

We introduce a model of infinite horizon linear dynamic optimization with linear constraints and obtain results concerning feasibility of trajectories and optimal solutions necessarily satisfying conditions that resemble the Euler condition…

Optimization and Control · Mathematics 2025-04-02 Somdeb Lahiri

We consider nonlinear elliptic systems satisfying componentwise coercivity condition. The nonlinear terms have controlled growths with respect to the solution and its gradient, while the behaviour in the independent variable is governed by…

Analysis of PDEs · Mathematics 2025-12-10 Lubomira Softova

In this series of papers, we present a motion planning framework for planning comfortable and customizable motion of nonholonomic mobile robots such as intelligent wheelchairs and autonomous cars. In Part I, we presented the mathematical…

Robotics · Computer Science 2013-05-23 Shilpa Gulati , Chetan Jhurani , Benjamin Kuipers

We consider the evolution by crystalline curvature of a planar set in a stratified medium, modeled by a periodic forcing term. We characterize the limit evolution law as the period of the oscillations tends to zero. Even if the model is…

Analysis of PDEs · Mathematics 2017-07-13 Andrea Braides , Annalisa Malusa , Matteo Novaga

Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this variability on buckling are unknown.…

Soft Condensed Matter · Physics 2025-12-12 Rahul G. Ramachandran , Ricard Alert , Pierre A. Haas

We consider birth and death stochastic dynamics of particle systems with attractive interaction. The heuristic generator of the dynamics has a constant birth rate and density dependent decreasing death rate. The corresponding statistical…

Mathematical Physics · Physics 2015-06-18 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Elena Zhizhina

We consider a stochastic Laplacian growth problem in the framework of normal random matrices. In the large $N$ limit the support of eigenvalues of random matrices is a planar domain with a sharp boundary which evolves under a change in the…

Mathematical Physics · Physics 2023-12-01 Oleg Alekseev

This paper studies a discrete-time version of the Lucas-Uzawa endogenous growth model with physical and human capital in the presence of externalities. Existence of an optimal equilibrium is proved using tools from dynamic programming with…

Theoretical Economics · Economics 2025-02-04 Luis Alcala