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Related papers: RealICU: Do LLM Agents Understand Long-Context ICU…

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To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and clinical practice,…

Machine Learning · Computer Science 2019-08-23 William Caicedo-Torres , Jairo Gutierrez

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Medical applications of machine learning (ML) have experienced a surge in popularity in recent years. The intensive care unit (ICU) is a natural habitat for ML given the abundance of available data from electronic health records. Models…

Machine Learning · Computer Science 2024-06-05 Robin van de Water , Hendrik Schmidt , Paul Elbers , Patrick Thoral , Bert Arnrich , Patrick Rockenschaub

As more Intensive Care Unit (ICU) data becomes available, the interest in developing clinical prediction models to improve healthcare protocols increases. However, the lack of data quality still hinders clinical prediction using Machine…

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

Time series data from the Intensive Care Unit (ICU) provides critical information for patient monitoring. While recent advancements in applying Large Language Models (LLMs) to time series modeling (TSM) have shown great promise, their…

Machine Learning · Computer Science 2026-01-27 Feixiang Zheng , Yu Wu , Cecilia Mascolo , Ting Dang

Large language models (LLMs) have made significant progress in Emotional Intelligence (EI) and long-context modeling. However, existing benchmarks often overlook the fact that emotional information processing unfolds as a continuous…

Computation and Language · Computer Science 2026-01-13 Weichu Liu , Jing Xiong , Yuxuan Hu , Zixuan Li , Minghuan Tan , Ningning Mao , Hui Shen , Wendong Xu , Chaofan Tao , Min Yang , Chengming Li , Lingpeng Kong , Ngai Wong

A seminal paper published by Ledley and Lusted in 1959 introduced complex clinical diagnostic reasoning cases as the gold standard for the evaluation of expert medical computing systems, a standard that has held ever since. Here, we report…

Progress of machine learning in critical care has been difficult to track, in part due to absence of public benchmarks. Other fields of research (such as computer vision and natural language processing) have established various competitions…

Machine Learning · Computer Science 2023-07-19 Seyedmostafa Sheikhalishahi , Vevake Balaraman , Venet Osmani

Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world…

Computation and Language · Computer Science 2025-10-24 Yunpeng Xiao , Carl Yang , Mark Mai , Xiao Hu , Kai Shu

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most…

Cryptography and Security · Computer Science 2025-12-10 Jinghao Wang , Ping Zhang , Carter Yagemann

Accurately predicting mortality risk in intensive care unit (ICU) patients is essential for clinical decision-making. Although large language models (LLMs) show strong potential in structured medical prediction tasks, their outputs may…

Machine Learning · Computer Science 2026-03-24 Gangxiong Zhang , Yongchao Long , Yuxi Zhou , Yong Zhang , Shenda Hong

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Integrating large language models into specialized domains like healthcare presents unique challenges, including domain adaptation and limited labeled data. We introduce CU-ICU, a method for customizing unsupervised instruction-finetuned…

Computation and Language · Computer Science 2025-07-21 Teerapong Panboonyuen

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Large language models (LLMs) are increasingly used for diagnostic tasks in medicine. In clinical practice, the correct diagnosis can rarely be immediately inferred from the initial patient presentation alone. Rather, reaching a diagnosis…

Artificial Intelligence · Computer Science 2026-02-20 Hui Min Wong , Philip Heesen , Pascal Janetzky , Martin Bendszus , Stefan Feuerriegel

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

Delirium is an acute confusional state that has been shown to affect up to 31% of patients in the intensive care unit (ICU). Early detection of this condition could lead to more timely interventions and improved health outcomes. While…

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang