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State-of-the-art backpropagation-free learning methods employ local error feedback to direct iterative optimisation via gradient descent. Here, we examine the more restrictive setting where retrograde communication from neuronal outputs is…

Machine Learning · Computer Science 2025-12-19 Robert O'Shea , Bipin Rajendran

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

Continuous monitoring of cardiac activity is paramount to understanding the functioning of the heart in addition to identifying precursors to conditions such as Atrial Fibrillation. Through continuous cardiac monitoring, early indications…

Machine Learning · Computer Science 2020-10-13 Prithvi Suresh , Naveen Narayanan , Chakilam Vijay Pranav , Vineeth Vijayaraghavan

Deep learning methods have reached state-of-the-art performance in cardiac image segmentation. Currently, the main bottleneck towards their effective translation into clinics requires assuring continuous high model performance and…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Francesco Galati , Maria A. Zuluaga

Models of electrical excitation and recovery in the heart have become increasingly detailed, but have yet to be used routinely in the clinical setting to guide personalized intervention in patients. One of the main challenges is calibrating…

Electrocardiography (ECG) signal is a highly applied measurement for individual heart condition, and much effort have been endeavored towards automatic heart arrhythmia diagnosis based on machine learning. However, traditional machine…

Signal Processing · Electrical Eng. & Systems 2021-11-01 Ziyu Liu , Xiang Zhang

Current deep learning algorithms designed for automatic ECG analysis have exhibited notable accuracy. However, akin to traditional electrocardiography, they tend to be narrowly focused and typically address a singular diagnostic condition.…

Signal Processing · Electrical Eng. & Systems 2024-05-14 Nils Strodthoff , Juan Miguel Lopez Alcaraz , Wilhelm Haverkamp

The extracellular space has an ambiguous role in neuroscience. It is present in every physiologically relevant system and often used as a measurement site in experimental recordings, but it has received subordinate attention compared to the…

Neurons and Cognition · Quantitative Biology 2017-05-02 Jurgis Pods

In modern neuroscience, functional magnetic resonance imaging (fMRI) has been a crucial and irreplaceable tool that provides a non-invasive window into the dynamics of whole-brain activity. Nevertheless, fMRI is limited by hemodynamic…

Signal Processing · Electrical Eng. & Systems 2024-01-26 Yamin Li , Ange Lou , Ziyuan Xu , Shiyu Wang , Catie Chang

In the context of electroencephalogram (EEG)-based driver drowsiness recognition, it is still challenging to design a calibration-free system, since EEG signals vary significantly among different subjects and recording sessions. Many…

Signal Processing · Electrical Eng. & Systems 2022-02-21 Jian Cui , Zirui Lan , Olga Sourina , Wolfgang Müller-Wittig

Objective skill assessment in high-stakes procedural environments requires models that not only decode underlying cognitive and motor processes but also generalize across tasks, individuals, and experimental contexts. While prior work has…

Signal Processing · Electrical Eng. & Systems 2025-07-01 A. Subedi , S. De , L. Cavuoto , S. Schwaitzberg , M. Hackett , J. Norfleet

Parameter estimation and uncertainty quantification are crucial in computational cardiology, as they enable the construction of digital twins that faithfully replicate the behavior of physical patients. Robust and efficient mathematical…

Numerical Analysis · Mathematics 2022-10-07 Matteo Salvador , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

Inverse problems describe the task of recovering an underlying signal of interest given observables. Typically, the observables are related via some non-linear forward model applied to the underlying unknown signal. Inverting the non-linear…

Signal Processing · Electrical Eng. & Systems 2023-05-19 Jihui Jin , Etienne Ollivier , Richard Touret , Matthew McKinley , Karim G. Sabra , Justin K. Romberg

Acoustic signals are crucial for health monitoring, particularly heart sounds which provide essential data like heart rate and detect cardiac anomalies such as murmurs. This study utilizes a publicly available phonocardiogram (PCG) dataset…

Sound · Computer Science 2024-07-29 Jingping Nie , Ran Liu , Behrooz Mahasseni , Erdrin Azemi , Vikramjit Mitra

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

This study focuses on inverting time-domain airborne electromagnetic data in 2D by training a neural-network to understand the relationship between data and conductivity, thereby removing the need for expensive forward modeling during the…

We propose a deep learning method to model and generate synthetic aortic shapes based on representing shapes as the zero-level set of a neural signed distance field, conditioned by a family of trainable embedding vectors with encode the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Andrei Gasparovici , Alex Serban

Electroanatomic mapping as routinely acquired in ablation therapy of ventricular tachycardia is the gold standard method to identify the arrhythmogenic substrate. To reduce the acquisition time and still provide maps with high spatial…

Atrial fibrillation is a commonly encountered clinical arrhythmia associated with stroke and increased mortality. Since professional medical knowledge is required for annotation, exploiting a large corpus of ECGs to develop accurate…

Quantitative Methods · Quantitative Biology 2024-10-25 Xiangqian Zhu , Mengnan Shi , Xuexin Yu , Chang Liu , Xiaocong Lian , Jintao Fei , Jiangying Luo , Xin Jin , Ping Zhang , Xiangyang Ji

Electrocardiogram recognition of cardiac arrhythmias is critical for cardiac abnormality diagnosis. Because of their strong prediction characteristics, artificial neural networks are the preferred method in medical diagnosis systems. This…

Signal Processing · Electrical Eng. & Systems 2021-04-16 N. Korucuk , C. Polat , E. S. Gunduz , O. Karaman , V. Tosun , M. Onac , N. Yildirim , Y. Cete , K. Polat