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Physics-Informed Neural Networks (PINNs) and Neural Ordinary Differential Equations (NODEs) represent two distinct machine learning frameworks for modeling nonlinear neuronal dynamics. This study systematically evaluates their performance…

Dynamical Systems · Mathematics 2026-03-31 Nikolaos M. Matzakos , Chrisovalantis Sfyrakis

Neural ordinary differential equations (NODEs) have been proven useful for learning non-linear dynamics of arbitrary trajectories. However, current NODE methods capture variations across trajectories only via the initial state value or by…

Machine Learning · Computer Science 2023-11-14 Ilze Amanda Auzina , Çağatay Yıldız , Sara Magliacane , Matthias Bethge , Efstratios Gavves

Solving inverse problems in dynamical systems governed by high-dimensional coupled ordinary differential equations (ODEs) is a ubiquitous challenge in scientific machine learning. In many real-world applications, researchers seek to uncover…

Machine Learning · Computer Science 2026-05-06 Zhao Wei , Kenneth Hor Cheng Koh , Sheng Yuan Chin , James Chun Yip Chan , Chin Chun Ooi , Yew-Soon Ong

Neural differential equations offer a powerful framework for modeling continuous-time dynamics, but forecasting stiff biophysical systems remains unreliable. Standard Neural ODEs and physics informed variants often require orders of…

Machine Learning · Computer Science 2025-11-18 Kamalpreet Singh Kainth , Prathamesh Dinesh Joshi , Raj Abhijit Dandekar , Rajat Dandekar , Sreedat Panat

Training dynamic models, such as neural ODEs, on long trajectories is a hard problem that requires using various tricks, such as trajectory splitting, to make model training work in practice. These methods are often heuristics with poor…

Machine Learning · Computer Science 2023-02-09 Valerii Iakovlev , Cagatay Yildiz , Markus Heinonen , Harri Lähdesmäki

Learning models of dynamical systems with external inputs, which may be, for example, nonsmooth or piecewise, is crucial for studying complex phenomena and predicting future state evolution, which is essential for applications such as…

Machine Learning · Computer Science 2025-04-16 Zhaoyi Li , Wenjie Mei , Ke Yu , Yang Bai , Shihua Li

In multi-body dynamics, the motion of a complicated physical object is described as a coupled ordinary differential equation system with multiple unknown solutions. Engineers need to constantly adjust the object to meet requirements at the…

Computational Engineering, Finance, and Science · Computer Science 2022-05-26 Wenhao Ding , Qing He , Hanghang Tong , Ping Wang

We describe a framework that can integrate prior physical information, e.g., the presence of kinematic constraints, to support data-driven simulation in multi-body dynamics. Unlike other approaches, e.g., Fully-connected Neural Network…

Computational Engineering, Finance, and Science · Computer Science 2024-07-12 Jingquan Wang , Shu Wang , Huzaifa Mustafa Unjhawala , Jinlong Wu , Dan Negrut

The predictive accuracy of operator learning frameworks depends on the quality and quantity of available training data (input-output function pairs), often requiring substantial amounts of high-fidelity data, which can be challenging to…

Machine Learning · Computer Science 2025-10-29 Sumanta Roy , Bahador Bahmani , Ioannis G. Kevrekidis , Michael D. Shields

When learning dynamical systems from data, embedding physical structure can constrain the solution space and improve generalization, but many physics-informed models assume access to the full system state. This limits their use in partially…

Machine Learning · Computer Science 2026-05-25 Sunniva Meltzer , Sølve Eidnes , Alexander Johannes Stasik

Despite the promise of scientific machine learning (SciML) in combining data-driven techniques with mechanistic modeling, existing approaches for incorporating hard constraints in neural differential equations (NDEs) face significant…

Machine Learning · Computer Science 2025-05-28 Avik Pal , Alan Edelman , Christopher Rackauckas

Model Predictive Control (MPC) is a state-of-the-art (SOTA) control technique which requires solving hard constrained optimization problems iteratively. For uncertain dynamics, analytical model based robust MPC imposes additional…

Robotics · Computer Science 2023-02-27 Sourav Sanyal , Kaushik Roy

Long-horizon motion forecasting for multiple autonomous robots is challenging due to non-linear agent interactions, compounding prediction errors, and continuous-time evolution of dynamics. Learned dynamics of such a system can be useful in…

Robotics · Computer Science 2025-10-02 Shounak Sural , Charles Kekeh , Wenliang Liu , Federico Pecora , Mouhacine Benosman

Ordinary differential equations (ODEs) describe dynamical systems evolving deterministically in continuous time. Accurate data-driven modeling of systems as ODEs, a central problem across the natural sciences, remains challenging,…

Machine Learning · Computer Science 2025-10-15 Maximilian Mauel , Manuel Hinz , Patrick Seifner , David Berghaus , Ramses J. Sanchez

A fundamental challenge in physics-informed machine learning (PIML) is the design of robust PIML methods for out-of-distribution (OOD) forecasting tasks. These OOD tasks require learning-to-learn from observations of the same (ODE)…

Machine Learning · Computer Science 2023-03-07 S Chandra Mouli , Muhammad Ashraful Alam , Bruno Ribeiro

Recent work in scientific machine learning has developed so-called physics-informed neural network (PINN) models. The typical approach is to incorporate physical domain knowledge as soft constraints on an empirical loss function and use…

Machine Learning · Computer Science 2021-11-12 Aditi S. Krishnapriyan , Amir Gholami , Shandian Zhe , Robert M. Kirby , Michael W. Mahoney

Neural operators have emerged as promising surrogate models for solving partial differential equations (PDEs), but struggle to generalise beyond training distributions and are often constrained to a fixed temporal discretisation. This work…

The order/dimension of models derived on the basis of data is commonly restricted by the number of observations, or in the context of monitored systems, sensing nodes. This is particularly true for structural systems (e.g., civil or…

Machine Learning · Computer Science 2022-12-01 Zhilu Lai , Wei Liu , Xudong Jian , Kiran Bacsa , Limin Sun , Eleni Chatzi

Neural Ordinary Differential Equations (NODEs) have proven to be a powerful modeling tool for approximating (interpolation) and forecasting (extrapolation) irregularly sampled time series data. However, their performance degrades…

Machine Learning · Computer Science 2020-04-29 Hammad A. Ayyubi , Yi Yao , Ajay Divakaran

Deep learning has an increasing impact to assist research, allowing, for example, the discovery of novel materials. Until now, however, these artificial intelligence techniques have fallen short of discovering the full differential equation…

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