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Computation methods for solving entropy-regularized reward optimization -- a class of problems widely used for fine-tuning generative models -- have advanced rapidly. Among those, Adjoint Matching (AM, Domingo-Enrich et al., 2025) has…

Machine Learning · Statistics 2026-02-17 Oswin So , Brian Karrer , Chuchu Fan , Ricky T. Q. Chen , Guan-Horng Liu

Atomistic foundation models (AFMs) have great promise as accurate interatomic potentials, and have enabled data-efficient molecular dynamics simulations with near quantum mechanical accuracy. However, AFMs remain markedly slower at…

Materials Science · Physics 2025-09-29 Lingyu Kong , Jaeheon Shim , Guoxiang Hu , Victor Fung

Recently, persistent homology has had tremendous success in biomolecular data analysis. It works by examining the topological relationship or connectivity of a group of atoms in a molecule at a variety of scales, then rendering a family of…

Biomolecules · Quantitative Biology 2019-03-27 David Bramer , Guo-Wei Wei

Atomistic machine learning (ML) is a powerful tool for accurate and efficient investigation of material behavior at the atomic scale. While such models have been constructed within Cartesian space to harness geometric information and…

Materials Science · Physics 2026-04-29 Qun Chen , A. S. L. Subrahmanyam Pattamatta , Boyu Wang , David J. Srolovitz , Mingjian Wen

The past few years have seen the development of ``universal'' machine-learning interatomic potentials (uMLIPs) capable of approximating the ground-state potential energy surface across a wide range of chemical structures and compositions…

Chemical Physics · Physics 2026-04-20 Sofiia Chorna , Davide Tisi , Cesare Malosso , Wei Bin How , Michele Ceriotti , Sanggyu Chong

Dissipative cognitive architectures maintain computation through continuous energy expenditure, where units that exhaust their energy are stochastically replaced with fresh random state. This creates a fundamental challenge: how can…

Neural and Evolutionary Computing · Computer Science 2026-03-31 Jianwei Lou

Understanding the dynamic transition of motifs in temporal graphs is essential for revealing how graph structures evolve over time, identifying critical patterns, and predicting future behaviors, yet existing methods often focus on…

Databases · Computer Science 2025-08-19 Zhiyuan Zheng , Jianpeng Qi , Jiantao Li , Guoqing Chao , Junyu Dong , Yanwei Yu

Electromagnetically induced transparency (EIT) in $\Lambda$-type atomic systems underpins quantum technologies such as high-fidelity memory and nonlinear optics, but conventional setups face intrinsic limitations. Standard geometries of…

Quantum Physics · Physics 2026-01-05 Thi Phuong Anh Nguyen , Le Phuong Hoang , Xuan Binh Cao

Sample efficiency is a fundamental challenge in de novo molecular design. Ideally, molecular generative models should learn to satisfy a desired objective under minimal oracle evaluations (computational prediction or wet-lab experiment).…

Biomolecules · Quantitative Biology 2023-05-26 Jeff Guo , Philippe Schwaller

Molecular dynamics simulations demand an unprecedented combination of accuracy and scalability to tackle grand challenges in catalysis and materials design. To bridge this gap, we present AlphaNet, a local-frame-based equivariant model that…

Node classification on attributed networks is a semi-supervised task that is crucial for network analysis. By decoupling two critical operations in Graph Convolutional Networks (GCNs), namely feature transformation and neighborhood…

Machine Learning · Computer Science 2022-06-24 Jinsong Chen , Boyu Li , Qiuting He , Kun He

This work proposes a time series prediction method based on the kernel view of linear reservoirs. In particular, the time series motifs of the reservoir kernel are used as representational basis on which general readouts are constructed. We…

Machine Learning · Computer Science 2024-12-05 Peter Tino , Robert Simon Fong , Roberto Fabio Leonarduzzi

In this paper, we explore a novel image matting task aimed at achieving efficient inference under various computational cost constraints, specifically FLOP limitations, using a single matting network. Existing matting methods which have not…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Qinglin Liu , Zonglin Li , Xiaoqian Lv , Xin Sun , Ru Li , Shengping Zhang

Machine learning potentials (MLPs) trained on data from quantum-mechanics based first-principles methods can approach the accuracy of the reference method at a fraction of the computational cost. To facilitate efficient MLP-based molecular…

Materials Science · Physics 2021-08-17 Michael S. Chen , Tobias Morawietz , Hideki Mori , Thomas E. Markland , Nongnuch Artrith

Feature embedding-based methods have shown exceptional performance in detecting industrial anomalies by comparing features of target images with normal images. However, some methods do not meet the speed requirements of real-time inference,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Donghyeong Kim , Chaewon Park , Suhwan Cho , Sangyoun Lee

Probabilistic Manifold Decomposition (PMD)\cite{doi:10.1137/25M1738863}, developed in our earlier work, provides a nonlinear model reduction by embedding high-dimensional dynamics onto low-dimensional probabilistic manifolds. The PMD has…

Numerical Analysis · Mathematics 2026-01-13 Jiaming Guo , Dunhui Xiao

Parameter-efficient fine-tuning (PEFT) methods optimize large language models (LLMs) by modifying or introducing a small number of parameters to enhance alignment with downstream tasks. However, they can result in catastrophic forgetting,…

Computation and Language · Computer Science 2024-12-24 Xin Song , Zhikai Xue , Guoxiu He , Jiawei Liu , Wei Lu

Existing time series tokenization methods predominantly encode a constant number of samples into individual tokens. This inflexible approach can generate excessive tokens for even simple patterns like extended constant values, resulting in…

Machine Learning · Computer Science 2026-01-29 Leon Götz , Marcel Kollovieh , Stephan Günnemann , Leo Schwinn

Flow matching (FM) trains a time-dependent vector field that transports samples from a simple prior to a complex data distribution. However, for high-dimensional images, each training sample supervises only a single trajectory and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 George Stoica , Sayak Paul , Matthew Wallingford , Vivek Ramanujan , Abhay Nori , Winson Han , Ali Farhadi , Ranjay Krishna , Judy Hoffman

Deep neural networks conventionally employ end-to-end backpropagation for their training process, which lacks biological credibility and triggers a locking dilemma during network parameter updates, leading to significant GPU memory use.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Junhao Su , Changpeng Cai , Feiyu Zhu , Chenghao He , Xiaojie Xu , Dongzhi Guan , Chenyang Si