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In the detection of anemia, leukemia and other blood diseases, the number and type of leukocytes are essential evaluation parameters. However, the conventional leukocyte counting method is not only quite time-consuming but also error-prone.…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Haichao Cao , Hong Liu , Enmin Song

Diffusion MRI microstructure fitting is nonconvex and often performed voxelwise, which limits fiber peak recovery in narrow crossings. This work introduces PRISM, a differentiable analysis-by-synthesis framework that fits an explicit…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Mohamed Abouagour , Atharva Shah , Eleftherios Garyfallidis

Examining blood microscopic images for leukemia is necessary when expensive equipment for flow cytometry is unavailable. Automated systems can ease the burden on medical experts for performing this examination and may be especially helpful…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Jonas Prellberg , Oliver Kramer

In this paper, we present PRISM, a Promptable and Robust Interactive Segmentation Model, aiming for precise segmentation of 3D medical images. PRISM accepts various visual inputs, including points, boxes, and scribbles as sparse prompts, as…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects the white blood cells. ALL constitutes approximately 25% of pediatric cancers. Early diagnosis and treatment of ALL are crucial for improving patient outcomes. The…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Dimitris Papaioannou , Ioannis Christou , Nikos Anagnou , Aristotelis Chatziioannou

Automatic detection of leukemic B-lymphoblast cancer in microscopic images is very challenging due to the complicated nature of histopathological structures. To tackle this issue, an automatic and robust diagnostic system is required for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Acute Lymphoblastic Leukemia (ALL) is a blood cell cancer characterized by numerous immature lymphocytes. Even though automation in ALL prognosis is an essential aspect of cancer diagnosis, it is challenging due to the morphological…

Image and Video Processing · Electrical Eng. & Systems 2021-05-11 Chayan Mondal , Md. Kamrul Hasan , Md. Tasnim Jawad , Aishwariya Dutta , Md. Rabiul Islam , Md. Abdul Awal , Mohiuddin Ahmad

Developing reliable and generalizable deep learning systems for medical imaging faces significant obstacles due to spurious correlations, data imbalances, and limited text annotations in datasets. Addressing these challenges requires…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Amar Kumar , Anita Kriz , Mohammad Havaei , Tal Arbel

Multivariate time series classification supports applications from wearable sensing to biomedical monitoring and demands models that can capture both short-term patterns and multi-scale temporal dependencies. Despite recent advances,…

Machine Learning · Computer Science 2026-04-07 Federico Zucchi , Thomas Lampert

Acute Lymphoblastic Leukemia (ALL) is one of the most common types of childhood blood cancer. The quick start of the treatment process is critical to saving the patient's life, and for this reason, early diagnosis of this disease is…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Amirhossein Askari Farsangi , Ali Sharifi-Zarchi , Mohammad Hossein Rohban

In this paper, we propose Precision-Informed Semantic Modeling (PRISM), a structured topic modeling framework combining the benefits of rich representations captured by LLMs with the low cost and interpretability of latent semantic…

Machine Learning · Computer Science 2026-04-06 Connor Douglas , Utkucan Balci , Joseph Aylett-Bullock

Acute lymphoblastic leukemia (ALL) is the most malignant form of leukemia and the most common cancer in adults and children. Traditionally, leukemia is diagnosed by analyzing blood and bone marrow smears under a microscope, with additional…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Maksuda Akter , Rabea Khatun , Md Manowarul Islam

Medical image segmentation is a relevant problem, with deep learning being an exponent. However, the necessity of a high volume of fully annotated images for training massive models can be a problem, especially for applications whose images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Matheus A. Cerqueira , Flávia Sprenger , Bernardo C. A. Teixeira , Alexandre X. Falcão

Automated interpretability research aims to identify concepts encoded in neural network features to enhance human understanding of model behavior. Within the context of large language models (LLMs) for natural language processing (NLP),…

Machine Learning · Computer Science 2025-11-13 Laura Kopf , Nils Feldhus , Kirill Bykov , Philine Lou Bommer , Anna Hedström , Marina M. -C. Höhne , Oliver Eberle

This paper features convolutional neural networks defined on hypercomplex algebras applied to classify lymphocytes in blood smear digital microscopic images. Such classification is helpful for the diagnosis of acute lymphoblast leukemia…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Guilherme Vieira , Marcos Eduardo Valle

Crystal structures are characterised by repeating atomic patterns within unit cells across three-dimensional space, posing unique challenges for graph-based representation learning. Current methods often overlook essential periodic boundary…

While optical microscopy inspection of blood films and bone marrow aspirates by a hematologist is a crucial step in establishing diagnosis of acute leukemia, especially in low-resource settings where other diagnostic modalities might not be…

Accurately retrieving images that are semantically similar remains a fundamental challenge in computer vision, as traditional methods often fail to capture the relational and contextual nuances of a scene. We introduce PRISm (Pruning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Dimitrios Georgoulopoulos , Nikolaos Chaidos , Angeliki Dimitriou , Giorgos Stamou

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Acute lymphoblastic leukemia (ALL) severity is determined by the presence and ratios of blast cells (abnormal white blood cells) in both bone marrow and peripheral blood. Manual diagnosis of this disease is a tedious and time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Amir Masoud Rahmani , Parisa Khoshvaght , Hamid Alinejad-Rokny , Samira Sadeghi , Parvaneh Asghari , Zohre Arabi , Mehdi Hosseinzadeh
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