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We explore how the fundamental problems in quantum molecular dynamics can be modelled using classical simulators (emulators) of quantum computers and the actual quantum hardware available to us today. The list of problems we tackle includes…

Quantum Physics · Physics 2025-07-29 Tamila Kuanysheva , Brian Kendrick , Lukasz Cincio , Dmitri Babikov

Determination of molecular energetics and properties is one of the core challenges in the near-term quantum computing. To this end, hybrid quantum-classical algorithms are preferred for Noisy Intermediate Scale Quantum (NISQ) architectures.…

Quantum Physics · Physics 2024-10-22 Dibyendu Mondal , Chayan Patra , Dipanjali Halder , Rahul Maitra

Computing ground-state properties of molecules is a promising application for quantum computers operating in concert with classical high-performance computing resources. Quantum embedding methods are a family of algorithms particularly…

We provide a systematic evaluation of the sample-based quantum diagonalization (SQD) method for electronic structure based on the W4-11 thermochemistry dataset, comprising 124 total atomization, 83 bond dissociation, 20 isomerization, 505…

Quantum Physics · Physics 2025-12-02 Osama M. Raisuddin , Haimeng Zhang , Mario Motta , Fabian M. Faulstich

In the Quantum-Train (QT) framework, mapping quantum state measurements to classical neural network weights is a critical challenge that affects the scalability and efficiency of hybrid quantum-classical models. The traditional QT framework…

Quantum Physics · Physics 2024-09-12 Chen-Yu Liu , Chu-Hsuan Abraham Lin , Kuan-Cheng Chen

Quantum computing promises revolutionary advances in modeling materials and molecules. However, the up-to-date runtime estimates for utility-scale applications on certain quantum hardware systems are in the order of years rendering quantum…

Quantum Physics · Physics 2025-11-21 Katerina Gratsea , Matthew Otten

In recent years, there has been an emerging trend of combining two innovations in computer science and physics to achieve better computation capability. Exploring the potential of quantum computation to achieve highly efficient performance…

Quantum Physics · Physics 2023-03-13 Yen-Jui Chang , Wei-Ting Wang , Hao-Yuan Chen , Shih-Wei Liao , Ching-Ray Chang

As quantum systems scale, Multiprogramming Quantum Computing (MPQC) becomes essential to improve device utilization and throughput. However, current MPQC pipelines rely on expensive online compilation to co-optimize concurrently running…

Hardware Architecture · Computer Science 2026-01-06 Yilun Zhao , Yu Chen , Kaiyan Chang , He Li , Bing Li , Yinhe Han , Ying Wang

Quantum computers represent a radical technological advancement in the way information is processed by using the principles of quantum mechanics to solve very complex problems that exceed the capabilities of classical systems. However, in…

Quantum Physics · Physics 2025-08-28 Marcos Guillermo Lammers , Federico Hernán Holik , Alejandro Fernández

In this work we investigate methods to improve the efficiency and scalability of quantum algorithms for quantum chemistry applications. We propose a transformation of the electronic structure Hamiltonian in the second quantization framework…

We propose a hybrid quantum-classical framework to solve the elastic scattering phase shift of two well-bound nuclei in an uncoupled channel. Within this framework, we develop a many-body formalism in which the continuum scattering states…

Nuclear Theory · Physics 2024-08-14 Peiyan Wang , Weijie Du , Wei Zuo , James P. Vary

Quantum computing has long been an experimental technology with the potential to simulate, at scale, phenomena which on classical devices would be too expensive to simulate at any but the smallest scales. Over the last several years,…

Quantum Physics · Physics 2025-02-06 Ivan Chernyshev

Neural network quantum state (NNQS) has emerged as a promising candidate for quantum many-body problems, but its practical applications are often hindered by the high cost of sampling and local energy calculation. We develop a…

Quantum Physics · Physics 2023-11-02 Yangjun Wu , Chu Guo , Yi Fan , Pengyu Zhou , Honghui Shang

Quantum computing offers a potential for algorithmic speedups for applications, such as large-scale simulations in chemistry and physics. However, these speedups must yield results that are sufficiently accurate to predict realistic…

Quantum Physics · Physics 2025-01-15 Meenambika Gowrishankar , Daniel Claudino , Jerimiah Wright , Travis Humble

Molecular ground-state simulation is one of the most promising fields for demonstrating practical quantum advantage on near-term quantum computers. However, the Variational Quantum Eigensolver (VQE), a leading algorithm for this task, still…

Quantum Physics · Physics 2025-07-08 Runhong He , Qiaozhen Chai , Xin Hong , Ji Guan , Guolong Cui , Shengbin Wang , Shenggang Ying

Rapid progress in noisy intermediate-scale quantum (NISQ) computing technology has led to the development of novel resource-efficient hybrid quantum-classical algorithms, such as the variational quantum eigensolver (VQE), that can address…

Strongly Correlated Electrons · Physics 2021-03-01 Yongxin Yao , Feng Zhang , Cai-Zhuang Wang , Kai-Ming Ho , Peter P. Orth

Applying quantum chemistry algorithms to large-scale systems requires substantial computational resources scaled with the system size and the desired accuracy. To address this, ByteQC, a fully-functional and efficient package for…

With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

Classical program analysis techniques, such as abstract interpretation and symbolic execution, are essential for ensuring software correctness, optimizing performance, and enabling compiler optimizations. However, these techniques face…

Quantum Physics · Physics 2025-10-14 Yicheng Guang , Pietro Zanotta , Kai Zhou , Yueqi Chen , Ramin Ayanzadeh

Quantum computing (QC) is a new paradigm offering the potential of exponential speedups over classical computing for certain computational problems. Each additional qubit doubles the size of the computational state space available to a QC…

Quantum Physics · Physics 2021-03-22 Wei Tang , Teague Tomesh , Martin Suchara , Jeffrey Larson , Margaret Martonosi