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Related papers: A clinical trial engineering firm

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The rapid advancement of large language models (LLMs) is fundamentally reshaping software engineering (SE), driving a paradigm shift in both academic research and industrial practice. While top-tier SE venues continue to show sustained or…

Software Engineering · Computer Science 2025-12-18 Hang Yu , Yuzhou Lai , Li Zhang , Xiaoli Lian , Fang Liu , Yanrui Dong , Ting Zhang , Zhi Jin , David Lo

The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…

Machine Learning · Computer Science 2025-03-14 Nabeel Seedat , Caterina Tozzi , Andrea Hita Ardiaca , Mihaela van der Schaar , James Weatherall , Adam Taylor

Traditionally, the detection of fraudulent insurance claims relies on business rules and expert judgement which makes it a time-consuming and expensive process (\'Oskarsd\'ottir et al., 2022). Consequently, researchers have been examining…

Machine Learning · Computer Science 2024-10-08 Bavo D. C. Campo , Katrien Antonio

Studies in socio-technical aspects of security often rely on user studies and statistical inferences on investigated relations to make their case. They, thereby, enable practitioners and scientists alike to judge on the validity and…

Cryptography and Security · Computer Science 2020-04-15 Thomas Groß

Reproducibility is central to the credibility of scientific findings, yet complete replication studies are costly and infrequent. However, many biological experiments contain internal replication, which is defined as repetition across…

Applications · Statistics 2025-06-05 Stanley E. Lazic

Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and…

Artificial Intelligence · Computer Science 2026-04-28 Aaryan Shah , Andrew Hines , Alexia Downs , Denis Bajet , Paulius Mui , Fabiano Araujo , Laura Offutt , Aida Rutledge , Elizabeth Jimenez

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

Computers and Society · Computer Science 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

There is overwhelming evidence that the continued and widespread use of untested spreadsheets in business gives rise to regular, significant and unexpected financial losses. Whilst this is worrying, it is perhaps a relatively minor concern…

Computers and Society · Computer Science 2024-12-31 Grenville J. Croll , Raymond J. Butler

Computational reproducibility is a growing problem that has been extensively studied among computational researchers and within the signal processing and machine learning research community. However, with the changing landscape of signal…

Signal Processing · Electrical Eng. & Systems 2022-02-16 Joseph Shenouda , Waheed U. Bajwa

The use of machine learning systems in clinical routine is still hampered by the necessity of a medical device certification and/or by difficulty to implement these systems in a clinic's quality management system. In this context, the key…

Medical Physics · Physics 2022-10-18 Lorenzo Mercolli , Axel Rominger , Kuangyu Shi

A profound gap persists between artificial intelligence (AI) and clinical practice in medicine, primarily due to the lack of rigorous and cost-effective evaluation methodologies. State-of-the-art and state-of-the-practice AI model…

As any scientific discipline, the software engineering (SE) research community strives to contribute to the betterment of the target population of our research: software producers and consumers. We will only achieve this betterment if we…

Software Engineering · Computer Science 2025-11-20 Julian Frattini , Hans-Martin Heyn , Robert Feldt , Richard Torkar

Reproducibility, the ability to reproduce the results of published papers or studies using their computer code and data, is a cornerstone of reliable scientific methodology. Studies where results cannot be reproduced by the scientific…

Applications · Statistics 2022-10-03 Xin Xiong , Ivor Cribben

Computational phenotyping has emerged as a practical solution to the incomplete collection of data on gender in electronic health records (EHRs). This approach relies on algorithms to infer a patient's gender using the available data in…

Research must be reproducible in order to make an impact on science and to contribute to the body of knowledge in our field. Yet studies have shown that 70% of research from academic labs cannot be reproduced. In software engineering, and…

Software Engineering · Computer Science 2018-04-10 Clinton Woodson , Jane Huffman Hayes , Sarah Griffioen

Randomized experiments are considered the gold standard for estimating causal effects. However, out of the set of possible randomized assignments, some may be likely to produce poor effect estimates and misleading conclusions. Restricted…

Methodology · Statistics 2025-08-28 Maggie Wang , René F. Kizilcec , Michael Baiocchi

The manual creation of system architecture diagrams for scientific papers is a time-consuming and subjective process, while existing generative models lack the necessary structural control and semantic understanding for this task. A primary…

Artificial Intelligence · Computer Science 2025-11-25 Ziyi Guo , Zhou Liu , Wentao Zhang

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

The Cancer Registry of Norway (CRN) uses an automated cancer registration support system (CaReSS) to support core cancer registry activities, i.e, data capture, data curation, and producing data products and statistics for various…

Software Engineering · Computer Science 2025-03-03 Erblin Isaku , Christoph Laaber , Hassan Sartaj , Shaukat Ali , Thomas Schwitalla , Jan F. Nygård

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti
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