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Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Low Dose Computed Tomography (LDCT) has offered tremendous benefits in radiation restricted applications, but the quantum noise as resulted by the insufficient number of photons could potentially harm the diagnostic performance. Current…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Xin Yi , Paul Babyn

Generative Adversarial Networks (GANs) have surfaced as a revolutionary element within the domain of low-dose computed tomography (LDCT) imaging, providing an advanced resolution to the enduring issue of reconciling radiation exposure with…

Image and Video Processing · Electrical Eng. & Systems 2025-02-05 Yunuo Wang , Ningning Yang , Jialin Li

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

Being low-level radiation exposure and less harmful to health, low-dose computed tomography (LDCT) has been widely adopted in the early screening of lung cancer and COVID-19. LDCT images inevitably suffer from the degradation problem caused…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Kecheng Chen , Jiayu Sun , Jiang Shen , Jixiang Luo , Xinyu Zhang , Xuelin Pan , Dongsheng Wu , Yue Zhao , Miguel Bento , Yazhou Ren , Xiaorong Pu

Reducing the radiation exposure for patients in Total-body CT scans has attracted extensive attention in the medical imaging community. Given the fact that low radiation dose may result in increased noise and artifacts, which greatly…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Minghan Fu , Yanhua Duan , Zhaoping Cheng , Wenjian Qin , Ying Wang , Dong Liang , Zhanli Hu

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

Low-dose computed tomography (LDCT) is an important topic in the field of radiology over the past decades. LDCT reduces ionizing radiation-induced patient health risks but it also results in a low signal-to-noise ratio (SNR) and a potential…

Image and Video Processing · Electrical Eng. & Systems 2022-10-03 Wenjun Xia , Qing Lyu , Ge Wang

Low dose computed tomography (LDCT) has attracted more and more attention in routine clinical diagnosis assessment, therapy planning, etc., which can reduce the dose of X-ray radiation to patients. However, the noise caused by low X-ray…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Zhicheng Zhang , Lequan Yu , Xiaokun Liang , Wei Zhao , Lei Xing

Computed tomography (CT) has been used worldwide as a non-invasive test to assist in diagnosis. However, the ionizing nature of X-ray exposure raises concerns about potential health risks such as cancer. The desire for lower radiation doses…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Yucheng Lu , Zhixin Xu , Moon Hyung Choi , Jimin Kim , Seung-Won Jung

Computed Tomography (CT) imposes risk on the patients due to its inherent X-ray radiation, stimulating the development of low-dose CT (LDCT) imaging methods. Lowering the radiation dose reduces the health risks but leads to noisier…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

Quantitative Methods · Quantitative Biology 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

To reduce radiation exposure and improve the diagnostic efficacy of low-dose computed tomography (LDCT), numerous deep learning-based denoising methods have been developed to mitigate noise and artifacts. However, most of these approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Runze Wang , Zeli Chen , Zhiyun Song , Wei Fang , Jiajin Zhang , Danyang Tu , Yuxing Tang , Minfeng Xu , Xianghua Ye , Le Lu , Dakai Jin

Computer-Aided-Diagnosis (CADx) systems assist radiologists with identifying and classifying potentially malignant pulmonary nodules on chest CT scans using morphology and texture-based (radiomic) features. However, radiomic features are…

Image and Video Processing · Electrical Eng. & Systems 2020-01-27 Leihao Wei , Yannan Lin , William Hsu

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

We propose a Noise Entangled GAN (NE-GAN) for simulating low-dose computed tomography (CT) images from a higher dose CT image. First, we present two schemes to generate a clean CT image and a noise image from the high-dose CT image. Then,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-22 Chuang Niu , Ge Wang , Pingkun Yan , Juergen Hahn , Youfang Lai , Xun Jia , Arjun Krishna , Klaus Mueller , Andreu Badal , KyleJ. Myers , Rongping Zeng

Low Dose Computed Tomography (LDCT) is clinically desirable due to the reduced radiation to patients. However, the quality of LDCT images is often sub-optimal because of the inevitable strong quantum noise. Inspired by their unprecedent…

Image and Video Processing · Electrical Eng. & Systems 2021-02-02 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Low-dose computed tomography (LDCT) scans, which can effectively alleviate the radiation problem, will degrade the imaging quality. In this paper, we propose a novel LDCT reconstruction network that unrolls the iterative scheme and performs…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Wenjun Xia , Zexin Lu , Yongqiang Huang , Zuoqiang Shi , Yan Liu , Hu Chen , Yang Chen , Jiliu Zhou , Yi Zhang