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Scribble-based weakly-supervised semantic segmentation using sparse scribble supervision is gaining traction as it reduces annotation costs when compared to fully annotated alternatives. Existing methods primarily generate pseudo-labels by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Xinliang Zhang , Lei Zhu , Hangzhou He , Lujia Jin , Yanye Lu

Stereotactic body radiation therapy (SBRT) for pancreatic cancer requires a skillful approach to deliver ablative doses to the tumor while limiting dose to the highly sensitive duodenum, stomach, and small bowel. Here, we develop…

Scribble-supervised semantic segmentation has gained much attention recently for its promising performance without high-quality annotations. Many approaches have been proposed. Typically, they handle this problem to either introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhiyi Pan , Peng Jiang , Changhe Tu

Structure-based drug design involves finding ligand molecules that exhibit structural and chemical complementarity to protein pockets. Deep generative methods have shown promise in proposing novel molecules from scratch (de-novo design),…

Quantitative Methods · Quantitative Biology 2021-11-09 Pavol Drotár , Arian Rokkum Jamasb , Ben Day , Cătălina Cangea , Pietro Liò

Radiation therapy is crucial in cancer treatment. Experienced experts typically iteratively generate high-quality dose distribution maps, forming the basis for excellent radiation therapy plans. Therefore, automated prediction of dose…

Image and Video Processing · Electrical Eng. & Systems 2025-01-23 Linjie Fu , Xia Li , Xiuding Cai , Yingkai Wang , Xueyao Wang , Yali Shen , Yu Yao

Machine learning approaches to Structure-Based Drug Design (SBDD) have proven quite fertile over the last few years. In particular, diffusion-based approaches to SBDD have shown great promise. We present a technique which expands on this…

Machine Learning · Computer Science 2024-07-01 Matan Halfon , Eyal Rozenberg , Ehud Rivlin , Daniel Freedman

Deep learning-based medical image segmentation helps assist diagnosis and accelerate the treatment process while the model training usually requires large-scale dense annotation datasets. Weakly semi-supervised medical image segmentation is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Shiman Li , Jiayue Zhao , Shaolei Liu , Xiaokun Dai , Chenxi Zhang , Zhijian Song

The integration of deep learning, particularly AI-Generated Content, with high-quality data derived from ab initio calculations has emerged as a promising avenue for transforming the landscape of scientific research. However, the challenge…

Machine Learning · Computer Science 2024-12-11 Kaiwei Zhang , Yange Lin , Guangcheng Wu , Yuxiang Ren , Xuecang Zhang , Bo wang , Xiaoyu Zhang , Weitao Du

Deep neural networks usually require accurate and a large number of annotations to achieve outstanding performance in medical image segmentation. One-shot segmentation and weakly-supervised learning are promising research directions that…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Wenhui Lei , Qi Su , Ran Gu , Na Wang , Xinglong Liu , Guotai Wang , Xiaofan Zhang , Shaoting Zhang

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

Semantic segmentation of medical images is a crucial step for the quantification of healthy anatomy and diseases alike. The majority of the current state-of-the-art segmentation algorithms are based on deep neural networks and rely on large…

Computer Vision and Pattern Recognition · Computer Science 2018-07-13 Yigit B. Can , Krishna Chaitanya , Basil Mustafa , Lisa M. Koch , Ender Konukoglu , Christian F. Baumgartner

Interactive 3D model texture editing presents enhanced opportunities for creating 3D assets, with freehand drawing style offering the most intuitive experience. However, existing methods primarily support sketch-based interactions for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Yudi Zhang , Yeming Geng , Lei Zhang

Recent works in automated radiotherapy treatment planning have used machine learning based on historical treatment plans to infer the spatial dose distribution for a novel patient directly from the planning image. We present an atlas-based…

Medical Physics · Physics 2017-08-02 Chris McIntosh , Mattea Welch , Andrea McNiven , David A. Jaffray , Thomas G. Purdie

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Structure-based drug design (SBDD) aims to generate ligands that bind strongly and specifically to target protein pockets. Recent diffusion models have advanced SBDD by capturing the distributions of atomic positions and types, yet they…

Machine Learning · Computer Science 2026-02-11 Yue Jian , Curtis Wu , Danny Reidenbach , Aditi S. Krishnapriyan

Recently unified generation and editing models have achieved remarkable success with their impressive performance. These models rely mainly on text prompts for instruction-based editing and generation, but language often fails to capture…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Bin Xia , Bohao Peng , Jiyang Liu , Sitong Wu , Jingyao Li , Junjia Huang , Xu Zhao , Yitong Wang , Ruihang Chu , Bei Yu , Jiaya Jia

Densely annotating LiDAR point clouds remains too expensive and time-consuming to keep up with the ever growing volume of data. While current literature focuses on fully-supervised performance, developing efficient methods that take…

Computer Vision and Pattern Recognition · Computer Science 2022-04-01 Ozan Unal , Dengxin Dai , Luc Van Gool

Scribble-based weakly supervised segmentation methods have shown promising results in medical image segmentation, significantly reducing annotation costs. However, existing approaches often rely on auxiliary tasks to enforce semantic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Zhisong Wang , Yiwen Ye , Ziyang Chen , Minglei Shu , Yanning Zhang , Yong Xia

Automated nodule segmentation is essential for computer-assisted diagnosis in ultrasound images. Nevertheless, most existing methods depend on precise pixel-level annotations by medical professionals, a process that is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xingyue Zhao , Peiqi Li , Xiangde Luo , Meng Yang , Shi Chang , Zhongyu Li

Segmenting anatomical structures and lesions from ultrasound images contributes to disease assessment. Weakly supervised learning (WSL) based on sparse annotation has achieved encouraging performance and demonstrated the potential to reduce…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Xiaoxiang Han , Xinyu Li , Jiang Shang , Yiman Liu , Keyan Chen , Shugong Xu , Qiaohong Liu , Qi Zhang