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Plant breeding and variety trials are usually conducted in multiple environments sampled from a defined target population of environments in order to characterize the performance of breeding lines or varieties. When the population is large…

Applications · Statistics 2026-05-01 Maryna Prus , Lenka Filová , Hans-Peter Piepho , Waqas Ahmed Malik

When setting up field experiments, to test and compare a range of genotypes (e.g. maize hybrids), it is important to account for any possible field effect that may otherwise bias performance estimates of genotypes. To do so, we propose a…

Neural and Evolutionary Computing · Computer Science 2019-07-23 Vitaliy Feoktistov , Stephane Pietravalle , Nicolas Heslot

Neural network models of real-world systems, such as industrial processes, made from sensor data must often rely on incomplete data. System states may not all be known, sensor data may be biased or noisy, and it is not often known which…

Neural and Evolutionary Computing · Computer Science 2007-06-08 Donald A. Sofge , David L. Elliott

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

New crop varieties are extensively tested in multi-environment trials in order to obtain a solid empirical basis for recommendations to farmers. When the target population of environments is large and heterogeneous, a division into…

Applications · Statistics 2020-04-14 Maryna Prus , Hans-Peter Piepho

Algorithms for machine learning-guided design, or design algorithms, use machine learning-based predictions to propose novel objects with desired property values. Given a new design task -- for example, to design novel proteins with high…

Machine Learning · Computer Science 2025-07-04 Clara Fannjiang , Ji Won Park

Growing mixtures of annual arable crop species or genotypes is a promising way to improve crop production without increasing agricultural inputs. To design optimal crop mixtures, choices of species, genotypes, sowing proportion, plant…

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

A crop can be represented as a biotechnical system in which components are either chosen (cultivar, management) or given (soil, climate) and whose combination generates highly variable stress patterns and yield responses. Here, we used…

Populations and Evolution · Quantitative Biology 2014-03-13 Pierre Casadebaig , Ronan Trépos , Victor Picheny , Nicolas B. Langlade , Patrick Vincourt , Philippe Debaeke

Motivated by modern applications such as computerized adaptive testing, sequential rank aggregation, and heterogeneous data source selection, we study the problem of active sequential estimation, which involves adaptively selecting…

Statistics Theory · Mathematics 2024-02-14 Xiaoou Li , Hongru Zhao

In the era of big data, analysts usually explore various statistical models or machine learning methods for observed data in order to facilitate scientific discoveries or gain predictive power. Whatever data and fitting procedures are…

Machine Learning · Statistics 2018-10-24 Jie Ding , Vahid Tarokh , Yuhong Yang

Training population selection for genomic selection has captured a great deal of interest in animal and plant breeding. In this article, we derive a computationally efficient statistic to measure the reliability of estimates of genetic…

Methodology · Statistics 2014-05-22 Deniz Akdemir

Maintaining genetic diversity as a means to avoid premature convergence is critical in Genetic Programming. Several approaches have been proposed to achieve this, with some focusing on the mating phase from coupling dissimilar solutions to…

Neural and Evolutionary Computing · Computer Science 2023-03-31 José Maria Simões , Nuno Lourenço , Penousal Machado

The emerging field of high-throughput compartmentalized in vitro evolution is a promising new approach to protein engineering. In these experiments, libraries of mutant genotypes are randomly distributed and expressed in microscopic…

Populations and Evolution · Quantitative Biology 2019-11-06 Anton S. Zadorin , Yannick Rondelez

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical…

Methodology · Statistics 2016-09-29 Marco Scutari , Ian Mackay , David Balding

Numerical plant models can predict the outcome of plant traits modifications resulting from genetic variations, on plant performance, by simulating physiological processes and their interaction with the environment. Optimization methods…

Quantitative Methods · Quantitative Biology 2017-06-20 Victor Picheny , Pierre Casadebaig , Ronan Trépos , Robert Faivre , David Da Silva , Patrick Vincourt , Evelyne Costes

Computational methods in drug repositioning can help to conserve resources. In particular, methods based on biological networks are showing promise. Considering only the network topology and knowledge on drug target genes is not sufficient…

Molecular Networks · Quantitative Biology 2025-04-02 Atte Aalto , La Mi , Diego A. Blanco-Mora , Jorge Goncalves

Microplastics contamination is one of the most rapidly growing research topics. However, monitoring microplastics contamination in the environment presents both logistical and statistical challenges, particularly when constrained resources…

Artificial Intelligence is increasingly pervasive across domains, with ever more complex models delivering impressive predictive performance. This fast technological advancement however comes at a concerning environmental cost, with…

Computers and Society · Computer Science 2025-09-25 Emilio Cruciani , Roberto Verdecchia
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