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Hybrid quantum-classical workflows combine quantum processing units (QPUs) with classical hardware to address computational tasks that are challenging or infeasible for conventional systems alone. Coordinating these heterogeneous resources…

Quantum Physics · Physics 2026-03-26 Mar Tejedor , Michele Grossi , Cenk Tüysüz , Ricardo Rocha , Sofia Vallecorsa

Quantum computers process information with the laws of quantum mechanics. Current quantum hardware is noisy, can only store information for a short time, and is limited to a few quantum bits, i.e., qubits, typically arranged in a planar…

Split-execution computing leverages the capabilities of multiple computational models to solve problems, but splitting program execution across different computational models incurs costs associated with the translation between domains. We…

Emerging Technologies · Computer Science 2016-09-26 Travis S. Humble , Alexander J. McCaskey , Jonathan Schrock , Hadayat Seddiqi , Keith A. Britt , Neena Imam

NISQ devices have several physical limitations and unavoidable noisy quantum operations, and only small circuits can be executed on a quantum machine to get reliable results. This leads to the quantum hardware under-utilization issue. Here,…

Hardware Architecture · Computer Science 2023-02-22 Siyuan Niu , Aida Todri-Sanial

Quantum processing unit (QPU) has to satisfy highly demanding quantity and quality requirements on its qubits to produce accurate results for problems at useful scales. Furthermore, classical simulations of quantum circuits generally do not…

Emerging Technologies · Computer Science 2022-07-05 Wei Tang , Margaret Martonosi

Quantum algorithms offer an exponential speedup over classical algorithms for a range of computational problems. The fundamental mechanisms underlying quantum computation required the development and construction of quantum computers. These…

Emerging Technologies · Computer Science 2025-06-12 Shane Sweeney , Krishnendu Guha

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and verification and validation. Despite considerable progress,…

Quantum Physics · Physics 2018-05-24 Alexander McCaskey , Eugene Dumitrescu , Dmitry Liakh , Travis Humble

Due to the scarcity of quantum computing resources, researchers and developers have very limited access to real quantum computers. Therefore, judicious planning and utilization of quantum computer runtime are essential to ensure smooth…

Software Engineering · Computer Science 2025-11-18 Ning Ma , Heng Li

Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

This paper introduces a vision for Quantum Software Development lifecycle, proposing a hybrid full-stack iterative model that integrates quantum and classical computing. Addressing the current challenges in Quantum Computing (QC) such as…

Software Engineering · Computer Science 2025-04-09 Arif Ali Khan , Davide Taibi , Muhammad Azeem Akbar

A strategy for the orchestration of hybrid classical-quantum workloads on supercomputers featuring quantum devices is proposed. The method makes use of heterogeneous job launches with Slurm to interleave classical and quantum computation,…

Quantum Physics · Physics 2023-12-11 Aniello Esposito , Sebastien Cabaniols , Jessica R. Jones , David Brayford

As quantum computing moves from isolated experiments toward integration with large-scale workflows, the integration of quantum devices into HPC systems has gained much interest. Quantum cloud providers expose shared devices through…

Quantum Physics · Physics 2026-04-10 Sinan Pehlivanoglu , Ulrik de Muelenaere , Peter Kogge , Amr Sabry

The quantum computing community is increasingly positioning quantum processors as accelerators within classical HPC workflows, analogous to GPUs and TPUs. However, many real-world applications require scaling to hundreds or thousands of…

Quantum Physics · Physics 2026-04-14 Vinooth Kulkarni , Aaron Orenstein , Xinpeng Li , Shuai Xu , Daniel Blankenberg , Vipin Chaudhary

Quantum computing enables parallelism through superposition and entanglement and offers advantages over classical computing architectures. However, due to the limitations of current quantum hardware in the noisy intermediate-scale quantum…

Quantum Physics · Physics 2025-09-09 Guolong Zhong , Yi Fan , Zhenyu Li

In emerging quantum-classical integration applications, the classical time cost-especially from compilation and protocol-level communication often exceeds the execution time of quantum circuits themselves, posing a severe bottleneck to…

Programming Languages · Computer Science 2025-06-16 Tianrui Zou , Yuan Fang , Jing Wang , Menghan Dou , Jun Fu , ZiQiang Zhao , ShuBin Zhao , Lei Yu , Dongyi Zhao , Zhaoyun Chen , Guoping Guo

Cutting edge classical computing today relies on a combination of CPU-based computing with a strong reliance on accelerators. In particular, high-performance computing (HPC) and machine learning (ML) rely heavily on acceleration via GPUs…

Quantum Physics · Physics 2026-03-11 Atulya Mahesh , Swastik Mittal , Frank Mueller

Developing state-of-the-art classical simulators of quantum circuits is of utmost importance to test and evaluate early quantum technology and understand the true potential of full-blown error-corrected quantum computers. In the past few…

Quantum Physics · Physics 2022-01-03 Salvatore Mandrà , Jeffrey Marshall , Eleanor G. Rieffel , Rupak Biswas

To harness the power of quantum computing (QC) in the near future, tight and efficient integration of QC with high performance computing (HPC) infrastructure (both on the software (SW) and the hardware (HW) level) is crucial. This paper…

Emerging Technologies · Computer Science 2024-07-29 Amr Elsharkawy , Xiaorang Guo , Martin Schulz

We present a multi-level quantum-classical intermediate representation (IR) that enables an optimizing, retargetable, ahead-of-time compiler for available quantum programming languages. To demonstrate our architecture, we leverage our…

Quantum Physics · Physics 2021-09-02 Thien Nguyen , Alexander McCaskey

In this paper, a novel quantum classical hybrid framework is proposed that synergizes quantum with Classical Reinforcement Learning. By leveraging the inherent parallelism of quantum computing, the proposed approach generates robust Q…

Machine Learning · Computer Science 2025-05-21 Sahil Tomar , Shamshe Alam , Sandeep Kumar , Amit Mathur