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We present an effective model for timing-dependent synaptic plasticity (STDP) in terms of two interacting traces, corresponding to the fraction of activated NMDA receptors and the Ca2+ concentration in the dendritic spine of the…

Neurons and Cognition · Quantitative Biology 2015-02-26 Rodrigo Echeveste , Claudius Gros

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

Neurons and Cognition · Quantitative Biology 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

Spiking Neural Networks (SNNs), recognized for their biological plausibility and energy efficiency, employ sparse and asynchronous spikes for communication. However, the training of SNNs encounters difficulties coming from…

Neurons and Cognition · Quantitative Biology 2024-05-09 Sushant Yadav , Santosh Chaudhary , Rajesh Kumar

The escalating energy demands of artificial intelligence pose a critical challenge to conventional computing. Leveraging the efficiency of event-driven, in-memory neuromorphic architectures into the superconducting circuits with ultra-high…

Emerging Technologies · Computer Science 2026-04-07 Muen Wang , Shucheng Yang , Yuxiang Lin , Yuntian Gao , Xue Zhang , Xiaoping Gao , Minghui Niu , Huanli Liu , Yikang Wan , Wei Peng , Jie Ren

Standard Spiking Neural Network (SNN) models typically neglect metabolic constraints, treating neurons as energetically unconstrained components. We bridge this gap by implementing a conductance-based leaky integrate-and-fire (gLIF)…

Neurons and Cognition · Quantitative Biology 2025-12-29 Ece Öner , Cenk Denktaş

We present two novel optimizations that accelerate clock-based spiking neural network (SNN) simulators. The first one targets spike timing dependent plasticity (STDP). It combines lazy- with event-driven plasticity and efficiently…

Neural and Evolutionary Computing · Computer Science 2022-02-21 Dennis Bautembach , Iason Oikonomidis , Antonis Argyros

Spike-Timing-Dependent Plasticity (STDP) is an unsupervised learning mechanism for Spiking Neural Networks (SNNs) that has received significant attention from the neuromorphic hardware community. However, scaling such local learning…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Sen Lu , Abhronil Sengupta

Spike-timing dependent plasticity (STDP) is an organizing principle of biological neural networks. While synchronous firing of neurons is considered to be an important functional block in the brain, how STDP shapes neural networks possibly…

Neurons and Cognition · Quantitative Biology 2009-05-20 Yuko K. Takahashi , Hiroshi Kori , Naoki Masuda

Metal-oxide memristors have emerged as promising candidates for hardware implementation of artificial synapses - the key components of high-performance, analog neuromorphic networks - due to their excellent scaling prospects. Since some…

Other Condensed Matter · Physics 2016-10-10 M. Prezioso , F. Merrikh-Bayat , B. Hoskins , K. Likharev , D. Strukov

Computation on a large volume of data at high speed and low power requires energy-efficient computing architectures. Spiking neural network (SNN) with bio-inspired spike-timing-dependent plasticity learning (STDP) is a promising solution…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Sahibia Kaur Vohra , Sherin A Thomas , Mahendra Sakare , Devarshi Mrinal Das

Spiking Neural Networks (SNNs), particularly Spiking Transformers, offer energy-efficient processing of event-based sensor data for healthcare applications. Yet current architectures are rigid: they are trained and deployed as static…

Neural and Evolutionary Computing · Computer Science 2026-05-15 Alberto Ancilotto , Gianluca Amprimo , Stefano Di Carlo , Elisabetta Farella

Spiking Neural Networks (SNNs) promise energy-efficient, sparse, biologically inspired computation. Training them with Backpropagation Through Time (BPTT) and surrogate gradients achieves strong performance but remains biologically…

Emerging Technologies · Computer Science 2025-11-17 Jiaqi Lin , Yi Jiang , Abhronil Sengupta

In this study, we propose and analyze in simulations a new, highly flexible method of implementing synaptic plasticity in a wafer-scale, accelerated neuromorphic hardware system. The study focuses on globally modulated STDP, as a special…

Neurons and Cognition · Quantitative Biology 2013-08-21 Simon Friedmann , Nicolas Frémaux , Johannes Schemmel , Wulfram Gerstner , Karlheinz Meier

Mixed-signal neuromorphic processors with brain-like organization and device physics offer an ultra-low-power alternative to the unsustainable developments of conventional deep learning and computing. However, realizing the potential of…

Neural and Evolutionary Computing · Computer Science 2022-08-05 Mattias Nilsson , Foteini Liwicki , Fredrik Sandin

In neural systems, synaptic plasticity is usually driven by spike trains. Due to the inherent noises of neurons, synapses and networks, spike trains typically exhibit externally uncontrollable variability such as spatial heterogeneity and…

Neurons and Cognition · Quantitative Biology 2015-06-18 Zedong Bi , Changsong Zhou , Hai-Jun Zhou

Memristors have been widely studied as artificial synapses in neuromorphic circuits, due to their functional similarity with biological synapses, low operating power, and high integration density. In this work, a memristive synapse,…

Emerging Technologies · Computer Science 2023-08-29 Y. Liu , D. Wang , Z. Dong , H. Xie , W. Zhao

Spiking Neural Networks (SNNs) emulate the integrated-fire-leak mechanism found in biological neurons, offering a compelling combination of biological realism and energy efficiency. In recent years, they have gained considerable research…

Neural and Evolutionary Computing · Computer Science 2024-06-06 Lihao Wang , Zhaofei Yu

Neuronal oscillations are closely related to the symptoms of Parkinson's disease (PD). In this study, we explore how random fluctuations (or "stochastic inputs") affect these oscillations in brain states, which reflect the collective…

Neurons and Cognition · Quantitative Biology 2025-02-24 Thoa Thieu , Roderick Melnik

Spiking Neural Networks (SNNs) have emerged as an attractive spatio-temporal computing paradigm for complex vision tasks. However, most existing works yield models that require many time steps and do not leverage the inherent temporal…

Neural and Evolutionary Computing · Computer Science 2022-10-25 Gourav Datta , Haoqin Deng , Robert Aviles , Peter A. Beerel

Brain-inspired computing proposes a set of algorithmic principles that hold promise for advancing artificial intelligence. They endow systems with self learning capabilities, efficient energy usage, and high storage capacity. A core concept…

Neural and Evolutionary Computing · Computer Science 2022-12-01 Younes Bouhadjar , Sebastian Siegel , Tom Tetzlaff , Markus Diesmann , Rainer Waser , Dirk J. Wouters