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In complex visual recognition tasks it is typical to adopt multiple descriptors, that describe different aspects of the images, for obtaining an improved recognition performance. Descriptors that have diverse forms can be fused into a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Andreas Spanias

High-throughput sequencing has transformed microbiome research, but it also produces inherently compositional data that challenge standard statistical and machine learning methods. In this work, we propose a multinomial classification…

Applications · Statistics 2025-12-23 R. Alberich , N. A. Cruz , R. Fernández , I. García Mosquera , A. Mir , F. Rosselló

Semantically meaningful sentence embeddings are important for numerous tasks in natural language processing. To obtain such embeddings, recent studies explored the idea of utilizing synthetically generated data from pretrained language…

Computation and Language · Computer Science 2022-08-31 Taehee Kim , ChaeHun Park , Jimin Hong , Radhika Dua , Edward Choi , Jaegul Choo

Alignment-based sequence similarity searches, while accurate for some type of sequences, can produce incorrect results when used on more divergent but functionally related sequences that have undergone the sequence rearrangements observed…

Genomics · Quantitative Biology 2015-01-21 Ivan Borozan , Stuart Watt , Vincent Ferretti

With the recent success of pre-trained models in NLP, a significant focus was put on interpreting their representations. One of the most prominent approaches is structural probing (Hewitt and Manning, 2019), where a linear projection of…

Computation and Language · Computer Science 2021-06-25 Tomasz Limisiewicz , David Mareček

Extreme low-data fine-grained classification is common in expert domains where labeling is expensive, yet practitioners still need principled guidance for selecting pretrained encoders. We study emerald inclusion grading with a custom…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Alexander Hackett , Srikanth Thudumu , Ginny Fisher , Jason Fisher

State-of-art speaker verification (SV) systems use a back-end model to score the similarity of speaker embeddings extracted from a neural network model. The commonly used back-end models are the cosine scoring and the probabilistic linear…

Sound · Computer Science 2022-04-25 Zhiyuan Peng , Xuanji He , Ke Ding , Tan Lee , Guanglu Wan

Functional peptides have the potential to treat a variety of diseases. Their good therapeutic efficacy and low toxicity make them ideal therapeutic agents. Artificial intelligence-based computational strategies can help quickly identify new…

Quantitative Methods · Quantitative Biology 2023-09-27 Zebin Ma , Yonglin Zou , Xiaobin Huang , Wenjin Yan , Hao Xu , Jiexin Yang , Ying Zhang , Jinqi Huang

Intrinsically disordered regions of proteins play a crucial role in cell signaling and drug discovery. However, their high structural flexibility makes accurate residue-level prediction challenging. Existing methods often rely on…

Neural and Evolutionary Computing · Computer Science 2026-03-09 Shaokuan Wang , Pengshan Cui , Yining Qian , An-Yang Lu , Xianpeng Wang

Decision trees and random forest remain highly competitive for classification on medium-sized, standard datasets due to their robustness, minimal preprocessing requirements, and interpretability. However, a single tree suffers from high…

Machine Learning · Statistics 2025-12-02 Cencheng Shen , Yuexiao Dong , Carey E. Priebe

Neural program embedding can be helpful in analyzing large software, a task that is challenging for traditional logic-based program analyses due to their limited scalability. A key focus of recent machine-learning advances in this area is…

Machine Learning · Computer Science 2019-05-29 Ke Wang , Mihai Christodorescu

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

The knowledge regarding the function of proteins is necessary as it gives a clear picture of biological processes. Nevertheless, there are many protein sequences found and added to the databases but lacks functional annotation. The…

Quantitative Methods · Quantitative Biology 2018-09-13 Anu Vazhayil , Vinayakumar R , Soman KP

A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional methods of characterization. Environmental shotgun sequencing…

Genomics · Quantitative Biology 2007-08-24 Sourav Chatterji , Ichitaro Yamazaki , Zhaojun Bai , Jonathan Eisen

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Proteins are biomolecules of life. They fold into a great variety of three-dimensional (3D) shapes. Underlying these folding patterns are many recurrent structural fragments or building blocks (analogous to `LEGO bricks'). This paper…

Quantitative Methods · Quantitative Biology 2013-10-08 Arun S. Konagurthu , Arthur M. Lesk , David Abramson , Peter J. Stuckey , Lloyd Allison

Pre-trained language models have demonstrated powerful capabilities in the field of natural language processing (NLP). Recently, code pre-trained model (PTM), which draw from the experiences of the NLP field, have also achieved…

Software Engineering · Computer Science 2023-11-15 Yu Zhao , Lina Gong , Haoxiang Zhang , Yaoshen Yu , Zhiqiu Huang

Over the past decade, the revolution in single-cell sequencing has enabled the simultaneous molecular profiling of various modalities across thousands of individual cells, allowing scientists to investigate the diverse functions of complex…

Computation and Language · Computer Science 2024-12-05 Junhao Liu , Siwei Xu , Lei Zhang , Jing Zhang

Data profilers play a crucial role in the preprocessing phase of data analysis by identifying quality issues such as missing, extreme, or erroneous values. Traditionally, profilers have relied solely on statistical methods, which lead to…

Databases · Computer Science 2024-04-22 Zezhou Huang , Eugene Wu

Standard plane recognition plays an important role in prenatal ultrasound (US) screening. Automatically recognizing the standard plane along with the corresponding anatomical structures in US image can not only facilitate US image…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Shuangchi He , Zehui Lin , Xin Yang , Chaoyu Chen , Jian Wang , Xue Shuang , Ziwei Deng , Qin Liu , Yan Cao , Xiduo Lu , Ruobing Huang , Nishant Ravikumar , Alejandro Frangi , Yuanji Zhang , Yi Xiong , Dong Ni