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Counterfactual medical image generation have emerged as a critical tool for enhancing AI-driven systems in medical domain by answering "what-if" questions. However, existing approaches face two fundamental limitations: First, they fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hyungi Min , Taeseung You , Hangyeul Lee , Yeongjae Cho , Sungzoon Cho

Counterfactual explanation is one branch of interpretable machine learning that produces a perturbation sample to change the model's original decision. The generated samples can act as a recommendation for end-users to achieve their desired…

Machine Learning · Computer Science 2023-03-28 Tri Dung Duong , Qian Li , Guandong Xu

One of the primary challenges limiting the applicability of deep learning is its susceptibility to learning spurious correlations rather than the underlying mechanisms of the task of interest. The resulting failure to generalise cannot be…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Damien Teney , Ehsan Abbasnedjad , Anton van den Hengel

Due to the common content of anatomy, radiology images with their corresponding reports exhibit high similarity. Such inherent data bias can predispose automatic report generation models to learn entangled and spurious representations…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Mingjie Li , Haokun Lin , Liang Qiu , Xiaodan Liang , Ling Chen , Abdulmotaleb Elsaddik , Xiaojun Chang

Conditional Generative Adversarial Networks (cGANs) extend the standard unconditional GAN framework to learning joint data-label distributions from samples, and have been established as powerful generative models capable of generating…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Ligong Han , Martin Renqiang Min , Anastasis Stathopoulos , Yu Tian , Ruijiang Gao , Asim Kadav , Dimitris Metaxas

The key to multi-label image classification (MLC) is to improve model performance by leveraging label correlations. Unfortunately, it has been shown that overemphasizing co-occurrence relationships can cause the overfitting issue of the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Ming-Kun Xie , Jia-Hao Xiao , Pei Peng , Gang Niu , Masashi Sugiyama , Sheng-Jun Huang

Generating safety-critical driving scenarios requires understanding why dangerous interactions arise, rather than merely forcing collisions. However, existing methods rely on heuristic adversarial agent selection and unstructured…

Robotics · Computer Science 2026-03-24 Bowen Jing , Ruiyang Hao , Weitao Zhou , Haibao Yu

Conditional image generation is the task of generating diverse images using class label information. Although many conditional Generative Adversarial Networks (GAN) have shown realistic results, such methods consider pairwise relations…

Computer Vision and Pattern Recognition · Computer Science 2021-02-04 Minguk Kang , Jaesik Park

Counterfactual reasoning -- the practice of asking ``what if'' by varying inputs and observing changes in model behavior -- has become central to interpretable and fair AI. This thesis develops frameworks that use counterfactuals to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Pushkar Shukla

This work showcases a new approach for causal discovery by leveraging user experiments and recent advances in photo-realistic image editing, demonstrating a potential of identifying causal factors and understanding complex systems…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Tao Li

Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

Counterfactual generation lies at the core of various machine learning tasks, including image translation and controllable text generation. This generation process usually requires the identification of the disentangled latent…

Machine Learning · Computer Science 2024-02-26 Hanqi Yan , Lingjing Kong , Lin Gui , Yuejie Chi , Eric Xing , Yulan He , Kun Zhang

Explanation techniques that synthesize small, interpretable changes to a given image while producing desired changes in the model prediction have become popular for introspecting black-box models. Commonly referred to as counterfactuals,…

Machine Learning · Computer Science 2021-10-06 Jayaraman J. Thiagarajan , Vivek Narayanaswamy , Deepta Rajan , Jason Liang , Akshay Chaudhari , Andreas Spanias

3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Counterfactuals, serving as one of the emerging type of model interpretations, have recently received attention from both researchers and practitioners. Counterfactual explanations formalize the exploration of ``what-if'' scenarios, and are…

Machine Learning · Computer Science 2021-06-17 Fan Yang , Sahan Suresh Alva , Jiahao Chen , Xia Hu

Answering counterfactual queries has important applications such as explainability, robustness, and fairness but is challenging when the causal variables are unobserved and the observations are non-linear mixtures of these latent variables,…

Machine Learning · Computer Science 2024-04-16 Zeyu Zhou , Ruqi Bai , Sean Kulinski , Murat Kocaoglu , David I. Inouye

In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

Performance monitoring is essential for safe clinical deployment of image classification models. However, because ground-truth labels are typically unavailable in the target dataset, direct assessment of real-world model performance is…

Machine Learning · Computer Science 2025-07-31 Tim Flühmann , Alceu Bissoto , Trung-Dung Hoang , Lisa M. Koch

Counterfactual image generation presents significant challenges, including preserving identity, maintaining perceptual quality, and ensuring faithfulness to an underlying causal model. While existing auto-encoding frameworks admit semantic…

Machine Learning · Computer Science 2025-06-10 Rajat Rasal , Avinash Kori , Fabio De Sousa Ribeiro , Tian Xia , Ben Glocker
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