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The automation of scientific discovery represents a critical milestone in Artificial Intelligence (AI) research. However, existing agentic systems for science suffer from two fundamental limitations: rigid, pre-programmed workflows that…

Artificial Intelligence · Computer Science 2025-10-20 Ed Li , Junyu Ren , Xintian Pan , Cat Yan , Chuanhao Li , Dirk Bergemann , Zhuoran Yang

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

We envision a continuous collaborative learning system where groups of LLM agents work together to solve reasoning problems, drawing on memory they collectively build to improve performance as they gain experience. This work establishes the…

Artificial Intelligence · Computer Science 2025-03-11 Julie Michelman , Nasrin Baratalipour , Matthew Abueg

Deep research systems powered by LLM agents have transformed complex information seeking by automating the iterative retrieval, filtering, and synthesis of insights from massive-scale web sources. However, existing systems predominantly…

Information Retrieval · Computer Science 2026-03-16 Bo Pan , Lunke Pan , Yitao Zhou , Qi Jiang , Zhen Wen , Minfeng Zhu , Wei Chen

Rapid advancements in large language models (LLMs) have the potential to assist in scientific progress. A critical capability toward this endeavor is the ability to reproduce existing work. To evaluate the ability of AI agents to reproduce…

As AI agents evolve, the community is rapidly shifting from single Large Language Models (LLMs) to Multi-Agent Systems (MAS) to overcome cognitive bottlenecks in automated research. However, the optimal multi-agent coordination framework…

Multiagent Systems · Computer Science 2026-05-12 Yang Shen , Zhenyi Yi , Ziyi Zhao , Lijun Sun , Dongyang Li , Chin-Teng Lin , Yuhui Shi

This paper introduces Agent-Based Auto Research, a structured multi-agent framework designed to automate, coordinate, and optimize the full lifecycle of scientific research. Leveraging the capabilities of large language models (LLMs) and…

Large Reasoning Models (LRMs) face two fundamental limitations: excessive token consumption when overanalyzing simple information processing tasks, and inability to access up-to-date knowledge beyond their training data. We introduce MARS…

Artificial Intelligence · Computer Science 2026-02-03 Guoxin Chen , Zile Qiao , Wenqing Wang , Donglei Yu , Xuanzhong Chen , Hao Sun , Minpeng Liao , Kai Fan , Yong Jiang , Penguin Xie , Wayne Xin Zhao , Ruihua Song , Fei Huang

Complex tasks are increasingly delegated to ensembles of specialized LLM-based agents that reason, communicate, and coordinate actions-both among themselves and through interactions with external tools, APIs, and databases. While persistent…

Multiagent Systems · Computer Science 2025-05-27 Alireza Rezazadeh , Zichao Li , Ange Lou , Yuying Zhao , Wei Wei , Yujia Bao

LLMs have made significant progress in complex but easy-to-verify problems, yet they still struggle with discovering the unknown. In this paper, we present \textbf{AlphaResearch}, an autonomous research agent designed to discover new…

Computation and Language · Computer Science 2026-04-02 Zhaojian Yu , Kaiyue Feng , Yilun Zhao , Shilin He , Xiao-Ping Zhang , Arman Cohan

AI agents increasingly operate over extended time horizons, yet their ability to retain, organize, and recall multimodal experiences remains a critical bottleneck. Building effective lifelong memory requires navigating a vast design space…

Artificial Intelligence · Computer Science 2026-04-03 Jiaqi Liu , Zipeng Ling , Shi Qiu , Yanqing Liu , Siwei Han , Peng Xia , Haoqin Tu , Zeyu Zheng , Cihang Xie , Charles Fleming , Mingyu Ding , Huaxiu Yao

Multi-agent systems powered by large language models have demonstrated remarkable capabilities across diverse domains, yet existing automated design approaches seek monolithic solutions that fail to adapt resource allocation based on query…

Artificial Intelligence · Computer Science 2025-10-06 Bo Ma , Hang Li , ZeHua Hu , XiaoFan Gui , LuYao Liu , Simon Liu

The rapid advancement of large language models (LLMs) has driven the development of agentic systems capable of autonomously performing complex tasks. Despite their impressive capabilities, LLMs remain constrained by their internal knowledge…

Information Retrieval · Computer Science 2025-08-19 Wenlin Zhang , Xiaopeng Li , Yingyi Zhang , Pengyue Jia , Yichao Wang , Huifeng Guo , Yong Liu , Xiangyu Zhao

Large language model (LLM) based recommendation agents personalize what they know through evolving per-user semantic memory, yet how they reason remains a universal, static system prompt shared identically across all users. This asymmetry…

Information Retrieval · Computer Science 2026-04-22 Zhen Tao , Riwei Lai , Chenyun Yu , Weixin Chen , Li Chen , Beibei Kong , Lei Cheng , Chengxiang Zhuo , Zang Li , Qingqiang Sun

Automating scientific discovery requires more than generating papers from ideas. Real research is iterative: hypotheses are challenged from multiple perspectives, experiments fail and inform the next attempt, and lessons accumulate across…

We present AutoResearch-RL, a framework in which a reinforcement learning agent conducts open-ended neural architecture and hyperparameter research without human supervision, running perpetually until a termination oracle signals…

Machine Learning · Computer Science 2026-03-20 Nilesh Jain , Rohit Yadav , Sagar Kotian , Claude AI

Long-term memory is essential for LLM agents that operate across multiple sessions, yet existing memory systems treat retrieval infrastructure as fixed: stored content evolves while scoring functions, fusion strategies, and…

Machine Learning · Computer Science 2026-05-15 Jiaqi Liu , Xinyu Ye , Peng Xia , Zeyu Zheng , Cihang Xie , Mingyu Ding , Huaxiu Yao

Despite the remarkable progress of large language models (LLMs), the capabilities of standalone LLMs have begun to plateau when tackling real-world, complex tasks that require interaction with external tools and dynamic environments.…

Deep research is an inherently challenging task that demands both breadth and depth of thinking. It involves navigating diverse knowledge spaces and reasoning over complex, multi-step dependencies, which presents substantial challenges for…

Memory serves as the pivotal nexus bridging past and future, providing both humans and AI systems with invaluable concepts and experience to navigate complex tasks. Recent research on autonomous agents has increasingly focused on designing…

Computation and Language · Computer Science 2025-12-30 Jiafeng Liang , Hao Li , Chang Li , Jiaqi Zhou , Shixin Jiang , Zekun Wang , Changkai Ji , Zhihao Zhu , Runxuan Liu , Tao Ren , Jinlan Fu , See-Kiong Ng , Xia Liang , Ming Liu , Bing Qin
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