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Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Many self-supervised denoising approaches have been proposed in recent years. However, these methods tend to overly smooth images, resulting in the loss of fine structures that are essential for medical applications. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Basar Demir , Yikang Liu , Xiao Chen , Eric Z. Chen , Lin Zhao , Boris Mailhe , Terrence Chen , Shanhui Sun

Fluoroscopy is critical for real-time X-ray visualization in medical imaging. However, low-dose images are compromised by noise, potentially affecting diagnostic accuracy. Noise reduction is crucial for maintaining image quality, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Sun-Young Jeon , Sen Wang , Adam S. Wang , Garry E. Gold , Jang-Hwan Choi

Synthetic X-ray images are simulated X-ray images projected from CT data. High-quality synthetic X-ray images can facilitate various applications such as surgical image guidance systems and VR training simulations. However, it is difficult…

Image and Video Processing · Electrical Eng. & Systems 2021-08-12 Qing Ma , Jae Chul Koh , WonSook Lee

Network reconstruction of dynamical continuous-time (CT) systems is motivated by applications in many fields. Due to experimental limitations, especially in biology, data could be sampled at low frequencies, leading to significant…

Systems and Control · Computer Science 2018-10-30 Zuogon Yue , Johan Thunberg , Lennart Ljung , Ye Yuan , Jorge Goncalves

In recent works, a flow-based neural vocoder has shown significant improvement in real-time speech generation task. The sequence of invertible flow operations allows the model to convert samples from simple distribution to audio samples.…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-18 Hyun-Wook Yoon , Sang-Hoon Lee , Hyeong-Rae Noh , Seong-Whan Lee

Current self-supervised denoising methods for paired noisy images typically involve mapping one noisy image through the network to the other noisy image. However, after measuring the spectral bias of such methods using our proposed Image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wang Zhang , Huaqiu Li , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

This study investigates the noise characteristics of intraoperative X-ray fluoroscopic images acquired during real-time image-guided radiotherapy (IGRT), and presents a novel noise image generation method based on the identified noise…

Medical Physics · Physics 2024-11-04 Yongxuan Yan , Fumitake Fujii , Takehiro Shiinoki

Speckle noise has long been an extensively studied problem in medical imaging. In recent years, there have been significant advances in leveraging deep learning methods for noise reduction. Nevertheless, adaptation of supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Deborah Pereg

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method…

Medical Physics · Physics 2016-10-04 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

With the great success of diffusion models in image generation, diffusion-based image compression is attracting increasing interests. However, due to the random noise introduced in the diffusion learning, they usually produce…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zhenyu Du , Yanbo Gao , Shuai Li , Yiyang Li , Hui Yuan , Mao Ye

Low Dose CT Denoising research aims to reduce the risks of radiation exposure to patients. Recently researchers have used deep learning to denoise low dose CT images with promising results. However, approaches that use mean-squared-error…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Sepehr Ataei , Javad Alirezaie , Paul Babyn

A novel method for noise reduction in the setting of curve time series with error contamination is proposed, based on extending the framework of functional principal component analysis (FPCA). We employ the underlying, finite-dimensional…

Methodology · Statistics 2023-07-06 Cees Diks , Bram Wouters

This paper strives to generate a synthetic computed tomography (CT) image from a magnetic resonance (MR) image. The synthetic CT image is valuable for radiotherapy planning when only an MR image is available. Recent approaches have made…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Zenglin Shi , Pascal Mettes , Guoyan Zheng , Cees Snoek

Developing a deep learning method for medical segmentation tasks heavily relies on a large amount of labeled data. However, the annotations require professional knowledge and are limited in number. Recently, semi-supervised learning has…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Wanqin Ma , Huifeng Yao , Yiqun Lin , Jiarong Guo , Xiaomeng Li

Recovering a high-quality image from noisy indirect measurements is an important problem with many applications. For such inverse problems, supervised deep convolutional neural network (CNN)-based denoising methods have shown strong…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Allard A. Hendriksen , Daniel M. Pelt , K. Joost Batenburg

This paper presents a novel frequency-domain approach for path following problem, specifically designed to handle paths described by discrete data. The proposed algorithm utilizes the fast Fourier Transform (FFT) to process the discrete…

Systems and Control · Electrical Eng. & Systems 2023-08-15 Zirui Chen , Zongyu Zuo

Fluorescence microscopy image (FMI) denoising faces critical challenges due to the compound mixed Poisson-Gaussian noise with strong spatial correlation and the impracticality of acquiring paired noisy/clean data in dynamic biomedical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-25 Jizhihui Liu , Qixun Teng , Qing Ma , Junjun Jiang

Radiomics is an active area of research in medical image analysis, the low reproducibility of radiomics has limited its applicability to clinical practice. This issue is especially prominent when radiomic features are calculated from noisy…

Quantitative Methods · Quantitative Biology 2021-08-16 Junhua Chen , Chong Zhang , Alberto Traverso , Ivan Zhovannik , Andre Dekker , Leonard Wee , Inigo Bermejo