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Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Multimodal Large Language Models (MLLMs) have seen growing adoption across various scientific disciplines. These advancements encourage the investigation of molecule-text modeling within synthetic chemistry, a field dedicated to designing…

Machine Learning · Computer Science 2024-06-21 He Cao , Yanjun Shao , Zhiyuan Liu , Zijing Liu , Xiangru Tang , Yuan Yao , Yu Li

Mixture-of-Experts (MoE) has emerged as a promising approach to scale up deep learning models due to its significant reduction in computational resources. However, the dynamic nature of MoE leads to load imbalance among experts, severely…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-16 Chenqi Zhao , Wenfei Wu , Linhai Song , Yuchen Xu , Yitao Yuan

Deep Neural Networks (DNNs) have been a large driver for AI breakthroughs in recent years. However, these models have been getting increasingly large as they become more accurate and safe. This means that their training becomes increasingly…

Machine Learning · Computer Science 2024-06-17 Samuel Horvath , Stefanos Laskaridis , Shashank Rajput , Hongyi Wang

Humans possess the capability to comprehend diverse modalities and seamlessly transfer information between them. In this work, we introduce ModaVerse, a Multi-modal Large Language Model (MLLM) capable of comprehending and transforming…

Computer Vision and Pattern Recognition · Computer Science 2024-04-05 Xinyu Wang , Bohan Zhuang , Qi Wu

To reduce the computational and memory overhead of Large Language Models, various approaches have been proposed. These include a) Mixture of Experts (MoEs), where token routing affects compute balance; b) gradual pruning of model…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-16 Mohamed Wahib , Muhammed Abdullah Soyturk , Didem Unat

Previous work has attempted to boost Large Language Model (LLM) performance on planning and scheduling tasks through a variety of prompt engineering techniques. While these methods can work within the distributions tested, they are neither…

Computation and Language · Computer Science 2024-11-25 Atharva Gundawar , Karthik Valmeekam , Mudit Verma , Subbarao Kambhampati

Recent breakthroughs in Large-scale language models (LLMs) have demonstrated impressive performance on various tasks. The immense sizes of LLMs have led to very high resource demand and cost for running the models. Though the models are…

Machine Learning · Computer Science 2024-03-05 Juntao Zhao , Borui Wan , Yanghua Peng , Haibin Lin , Chuan Wu

Multimodal large language models (MLLMs) have extended the success of large language models (LLMs) to multiple data types, such as image, text and audio, achieving significant performance in various domains, including multimodal…

Computation and Language · Computer Science 2025-06-03 Weiqi Feng , Yangrui Chen , Shaoyu Wang , Yanghua Peng , Haibin Lin , Minlan Yu

Expert parallelism is vital for effectively training Mixture-of-Experts (MoE) models, enabling different devices to host distinct experts, with each device processing different input data. However, during expert parallel training, dynamic…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-13 Xinyi Liu , Yujie Wang , Fangcheng Fu , Xuefeng Xiao , Huixia Li , Jiashi Li , Bin Cui

Multi-step tool orchestration remains challenging for LLMs, as state-of-the-art models frequently fail on full sequence execution due to parameter errors. Training for these workflows faces two obstacles: the lack of environments supporting…

Machine Learning · Computer Science 2026-04-08 Cheng Jiayang , Xin Liu , Zhihan Zhang , Haoyang Wen , Zixuan Zhang , Qingyu Yin , Shiyang Li , Priyanka Nigam , Bing Yin , Chao Zhang , Yangqiu Song

Multimodal learning has shown great potentials in numerous scenes and attracts increasing interest recently. However, it often encounters the problem of missing modality data and thus suffers severe performance degradation in practice. To…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Shicai Wei , Yang Luo , Chunbo Luo

Large language models (LLMs) can generate code rapidly but remain unreliable for scientific algorithms whose correctness depends on structural assumptions rarely explicit in the source literature. We introduce a multi-stage LLM-assisted…

Computational Physics · Physics 2026-04-13 Yi Zhou

Temporal knowledge graphs (TKGs) support reasoning over time-evolving facts, yet state-of-the-art models are often computationally heavy and costly to deploy. Existing compression and distillation techniques are largely designed for static…

Computation and Language · Computer Science 2026-02-17 Wang Xing , Wei Song , Siyu Lin , Chen Wu , Man Wang

Multimodal large language models (MLLMs) are built on text-only LLMs by incorporating additional modalities, enabling multimodal understanding and a broader range of applications. However, these additions introduce a previously unexplored…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-06 Mona Moghadampanah , Adib Rezaei Shahmirzadi , Farhana Amin , Dimitrios S. Nikolopoulos

Dramatic increases in the capabilities of neural network models in recent years are driven by scaling model size, training data, and corresponding computational resources. To develop the exceedingly large networks required in modern…

Machine Learning · Computer Science 2025-04-15 Jared Fernandez , Luca Wehrstedt , Leonid Shamis , Mostafa Elhoushi , Kalyan Saladi , Yonatan Bisk , Emma Strubell , Jacob Kahn

The computational and memory challenges of large language models (LLMs) have sparked several optimization approaches towards their efficient implementation. While prior LLM-targeted quantization, and prior works on sparse acceleration have…

Hardware Architecture · Computer Science 2025-03-18 Abhishek Moitra , Arkapravo Ghosh , Shrey Agarwal , Aporva Amarnath , Karthik Swaminathan , Priyadarshini Panda

Multimodal Large Language Models (MLLMs) power platforms like ChatGPT, Gemini, and Copilot, enabling richer interactions with text, images, and videos. These heterogeneous workloads introduce additional inference stages, such as vision…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-06 Konstantinos Papaioannou , Thaleia Dimitra Doudali

Transformer models have emerged as the leading approach for achieving state-of-the-art performance across various application domains, serving as the foundation for advanced large-scale deep learning (DL) models. However, efficiently…

Machine Learning · Computer Science 2024-09-06 Yujie Wang , Youhe Jiang , Xupeng Miao , Fangcheng Fu , Shenhan Zhu , Xiaonan Nie , Yaofeng Tu , Bin Cui

As Large Language Models (LLMs) are increasingly adopted in edge intelligence to power domain-specific applications and personalized services, the quality and efficiency of the LLM post-training phase-including fine-tuning and inference,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-19 Shaoyuan Huang , Yunfeng Zhao , Na Yan , Tiancheng Zhang , Xiaokai Wang , Xiaofei Wang , Wenyu Wang , Yansha Deng