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Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

Research on the co-optimization of soft robotic design and control requires rapid means for real-world validation. Existing creation pipelines do not allow for the swift prototyping of soft robots to quickly test various design…

Robotics · Computer Science 2022-02-02 Yu Zhang , Robert K. Katzschmann

Underwater surveys conducted using divers or robots equipped with customized camera payloads can generate a large number of images. Manual review of these images to extract ecological data is prohibitive in terms of time and cost, thus…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Scarlett Raine , Ross Marchant , Peyman Moghadam , Frederic Maire , Brett Kettle , Brano Kusy

Pose estimation serves as a cornerstone of computer vision for understanding animal posture, behavior, and welfare. Yet, agricultural applications remain constrained by the scarcity of large, annotated datasets for livestock, especially…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Mackenzie Tapp , Sibi Chakravarthy Parivendan , Kashfia Sailunaz , Suresh Neethirajan

Photo-identification (photo-id) is one of the main non-invasive capture-recapture methods utilised by marine researchers for monitoring cetacean (dolphin, whale, and porpoise) populations. This method has historically been performed…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Cameron Trotter , Nick Wright , A. Stephen McGough , Matt Sharpe , Barbara Cheney , Mònica Arso Civil , Reny Tyson Moore , Jason Allen , Per Berggren

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Yue Liu , Hossein Azizpour , Fredrik Strand , Kevin Smith

Intestinal parasitic infection leads to several morbidities to humans worldwide, especially in tropical countries. The traditional diagnosis usually relies on manual analysis from microscopic images which is prone to human error due to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-05 Thanaphon Suwannaphong , Sawaphob Chavana , Sahapol Tongsom , Duangdao Palasuwan , Thanarat H. Chalidabhongse , Nantheera Anantrasirichai

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

Biological Physics · Physics 2023-08-25 Mengyang Gu , Xinyi Fang , Yimin Luo

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can…

Computational Engineering, Finance, and Science · Computer Science 2015-10-20 Dagmar Iber , Zahra Karimaddini , Erkan Ünal

Artificial intelligence is nowadays used for cell detection and classification in optical microscopy, during post-acquisition analysis. The microscopes are now fully automated and next expected to be smart, to make acquisition decisions…

Datasets (semi-)automatically collected from the web can easily scale to millions of entries, but a dataset's usefulness is directly related to how clean and high-quality its examples are. In this paper, we describe and publicly release an…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Houda Alberts , Iacer Calixto

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

The aim of this study was to employ machine learning algorithms based on sensor behavior data for (1) early-onset detection of digital dermatitis (DD); and (2) DD prediction in dairy cows. With the ultimate goal to set-up early warning…

Machine Learning · Computer Science 2023-09-20 Jennifer Magana , Dinu Gavojdian , Yakir Menachem , Teddy Lazebnik , Anna Zamansky , Amber Adams-Progar

Automated analysis of tissue sections allows a better understanding of disease biology and may reveal biomarkers that could guide prognosis or treatment selection. In digital pathology, less abundant cell types can be of biological…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Yeman Brhane Hagos , Catherine SY Lecat , Dominic Patel , Lydia Lee , Thien-An Tran , Manuel Rodriguez- Justo , Kwee Yong , Yinyin Yuan

Motions of visually coupled zebrafish pairs are studied to understand the effects of information exchange on their behavior as a function of their minimal separation ($d$). We find that when $d$ is small, the pair can display a…

Biological Physics · Physics 2025-02-04 C. K. Chan , Hao-Yun Hsu

A comprehensive study on machine and deep learning techniques for classification of normal and abnormal cervical cells by using pap smear images from Herlev dataset results are presented. This dataset includes 917 images and 7 different…

Image and Video Processing · Electrical Eng. & Systems 2020-09-15 Abdurrahim Yilmaz , Ali Anil Demircali , Sena Kocaman , Huseyin Uvet

Machine learning offers potential solutions to current issues in industrial systems in areas such as quality control and predictive maintenance, but also faces unique barriers in industrial applications. An ongoing challenge is extreme…

Machine Learning · Computer Science 2026-01-15 Lesley Wheat , Martin v. Mohrenschildt , Saeid Habibi

Efficient and precise prediction of plasticity by data-driven models relies on appropriate data preparation and a well-designed model. Here we introduce an unsupervised machine learning-based data preparation method to maximize the…

Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…

Quantitative Methods · Quantitative Biology 2024-03-05 Baiyang Dai , Jiamin Yang , Hari Shroff , Patrick La Riviere