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Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Large vision-language models (LVLMs) have significantly improved multimodal reasoning tasks, such as visual question answering and image captioning. These models embed multimodal facts within their parameters, rather than relying on…

Computation and Language · Computer Science 2025-02-18 Shengkang Wang , Hongzhan Lin , Ziyang Luo , Zhen Ye , Guang Chen , Jing Ma

Large language models (LLMs) show promise in healthcare, but hallucinations remain a major barrier to clinical use. We present CHECK, a continuous-learning framework that integrates structured clinical databases with a classifier grounded…

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Despite their impressive ability to generate high-quality and fluent text, generative large language models (LLMs) also produce hallucinations: statements that are misaligned with established world knowledge or provided input context.…

Computation and Language · Computer Science 2025-01-15 Abhilasha Ravichander , Shrusti Ghela , David Wadden , Yejin Choi

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

As large language models (LLMs) evolve from conversational assistants into agents capable of handling complex tasks, they are increasingly deployed in high-risk domains. However, existing benchmarks largely rely on mixed queries and…

Computation and Language · Computer Science 2026-04-28 Yuhe Wu , Guangyu Wang , Yuran Chen , Jiatong Zhang , Yutong Zhang , Yujie Chen , Jiaming Shang , Guang Zhang , Zhuang Liu

Large language models (LLMs) can be prone to hallucinations - generating unreliable outputs that are unfaithful to their inputs, external facts or internally inconsistent. In this work, we address several challenges for post-hoc…

Computation and Language · Computer Science 2024-08-12 Simon Valentin , Jinmiao Fu , Gianluca Detommaso , Shaoyuan Xu , Giovanni Zappella , Bryan Wang

While Large Language Models (LLMs) have emerged as powerful foundational models to solve a variety of tasks, they have also been shown to be prone to hallucinations, i.e., generating responses that sound confident but are actually incorrect…

Computation and Language · Computer Science 2026-04-29 Jiawei Li , Akshayaa Magesh , Venugopal V. Veeravalli

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Reasoning Models (LRMs) have shown impressive capabilities in multi-step reasoning tasks. However, alongside these successes, a more deceptive form of model error has emerged--Reasoning Hallucination--where logically coherent but…

Artificial Intelligence · Computer Science 2025-05-20 Zhongxiang Sun , Qipeng Wang , Haoyu Wang , Xiao Zhang , Jun Xu

Multimodal Large Language Models (MLLMs) have unlocked powerful cross-modal capabilities, but still significantly suffer from hallucinations. As such, accurate detection of hallucinations in MLLMs is imperative for ensuring their…

Computation and Language · Computer Science 2025-11-18 Pinxue Guo , Chongruo Wu , Xinyu Zhou , Lingyi Hong , Zhaoyu Chen , Jinglun Li , Kaixun Jiang , Sen-ching Samson Cheung , Wei Zhang , Wenqiang Zhang

While medical Multimodal Large Language Models (MLLMs) have shown promise in assisting diagnosis, they still frequently generate hallucinated responses that appear linguistically plausible but lack visual evidence. Such hallucinations pose…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Jiayi Chen , Benteng Ma , Zehui Liao , Winston Chong , Yasmeen George , Jianfei Cai

Current evaluation paradigms for large language models (LLMs) represent a critical blind spot in AI research--relying on opaque numerical metrics that conceal fundamental limitations in spatial reasoning while providing no intuitive…

Computation and Language · Computer Science 2025-11-05 Liuhao Lin , Ke Li , Zihan Xu , Yuchen Shi , Yulei Qin , Yan Zhang , Xing Sun , Rongrong Ji

Large Vision-Language Models (LVLMs) integrate image encoders with Large Language Models (LLMs) to process multi-modal inputs and perform complex visual tasks. However, they often generate hallucinations by describing non-existent objects…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Yaqi Sun , Kyohei Atarashi , Koh Takeuchi , Hisashi Kashima

Multimodal large language models (MLLMs) have achieved strong performance on vision-language tasks but still struggle with fine-grained visual differences, leading to hallucinations or missed semantic shifts. We attribute this to…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Tianyi Bai , Yuxuan Fan , Jiantao Qiu , Fupeng Sun , Jiayi Song , Junlin Han , Zichen Liu , Conghui He , Wentao Zhang , Binhang Yuan

The main challenges hindering the adoption of deep learning-based systems in clinical settings are the scarcity of annotated data and the lack of interpretability and trust in these systems. Concept Bottleneck Models (CBMs) offer inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Cristiano Patrício , Luís F. Teixeira , João C. Neves

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

Computation and Language · Computer Science 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

Large Language Models (LLMs) and Large Reasoning Models (LRMs) offer transformative potential for high-stakes domains like finance and law, but their tendency to hallucinate, generating factually incorrect or unsupported content, poses a…

Artificial Intelligence · Computer Science 2026-01-16 Ahmad Pesaranghader , Erin Li