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Large Vision Language Models (LVLMs) are increasingly integral to healthcare applications, including medical visual question answering and imaging report generation. While these models inherit the robust capabilities of foundational Large…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jiawei Chen , Dingkang Yang , Tong Wu , Yue Jiang , Xiaolu Hou , Mingcheng Li , Shunli Wang , Dongling Xiao , Ke Li , Lihua Zhang

Vision-language models (VLMs) exhibit strong zero-shot generalization on natural images and show early promise in interpretable medical image analysis. However, existing benchmarks do not systematically evaluate whether these models truly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Tianhong Zhou , Yin Xu , Yingtao Zhu , Chuxi Xiao , Haiyang Bian , Lei Wei , Xuegong Zhang

Medical Large Language Models (MLLMs) play a crucial role in ophthalmic diagnosis, holding significant potential to address vision-threatening diseases. However, their accuracy is constrained by hallucinations stemming from limited…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Pan , Yang Bai , Ke Zou , Yang Zhou , Jun Zhou , Huazhu Fu , Yih-Chung Tham , Yong Liu

Large Vision Language Models (LVLMs) are becoming increasingly important in the medical domain, yet Medical LVLMs (Med-LVLMs) frequently generate hallucinations due to limited expertise and the complexity of medical applications. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Aofei Chang , Le Huang , Parminder Bhatia , Taha Kass-Hout , Fenglong Ma , Cao Xiao

Medical Large Language Models (MLLMs) have demonstrated potential in healthcare applications, yet their propensity for hallucinations -- generating medically implausible or inaccurate information -- presents substantial risks to patient…

Computation and Language · Computer Science 2025-04-01 Kaiwen Zuo , Yirui Jiang

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Vision-Language Models (VLMs) frequently "hallucinate" - generate plausible yet factually incorrect statements - posing a critical barrier to their trustworthy deployment. In this work, we propose a new paradigm for diagnosing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Lexiang Xiong , Qi Li , Jingwen Ye , Xinchao Wang

Medical Vision-Language Models (Med-VLMs) have achieved expert-level proficiency in interpreting diagnostic imaging. However, current models are predominantly trained on professional literature, limiting their ability to communicate…

Computation and Language · Computer Science 2026-04-08 Han Jang , Junhyeok Lee , Heeseong Eum , Kyu Sung Choi

Large Vision Language Models (LVLMs) have recently achieved superior performance in various tasks on natural image and text data, which inspires a large amount of studies for LVLMs fine-tuning and training. Despite their advancements, there…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zishan Gu , Changchang Yin , Fenglin Liu , Ping Zhang

Advancements in Large Language Models (LLMs) and their increasing use in medical question-answering necessitate rigorous evaluation of their reliability. A critical challenge lies in hallucination, where models generate plausible yet…

Computation and Language · Computer Science 2025-02-21 Shrey Pandit , Jiawei Xu , Junyuan Hong , Zhangyang Wang , Tianlong Chen , Kaidi Xu , Ying Ding

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li

The increasing use of vision-language models (VLMs) in healthcare applications presents great challenges related to hallucinations, in which the models may generate seemingly plausible results that are in fact incorrect. Such hallucinations…

Artificial Intelligence · Computer Science 2025-03-03 Qiao Yan , Yuchen Yuan , Xiaowei Hu , Yihan Wang , Jiaqi Xu , Jinpeng Li , Chi-Wing Fu , Pheng-Ann Heng

This research paper focuses on the challenges posed by hallucinations in large language models (LLMs), particularly in the context of the medical domain. Hallucination, wherein these models generate plausible yet unverified or incorrect…

Computation and Language · Computer Science 2023-10-17 Ankit Pal , Logesh Kumar Umapathi , Malaikannan Sankarasubbu

We introduce HallusionBench, a comprehensive benchmark designed for the evaluation of image-context reasoning. This benchmark presents significant challenges to advanced large visual-language models (LVLMs), such as GPT-4V(Vision), Gemini…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Tianrui Guan , Fuxiao Liu , Xiyang Wu , Ruiqi Xian , Zongxia Li , Xiaoyu Liu , Xijun Wang , Lichang Chen , Furong Huang , Yaser Yacoob , Dinesh Manocha , Tianyi Zhou

Large language models (LLMs) have achieved strong performance on medical exam-style tasks, motivating growing interest in their deployment in real-world clinical settings. However, clinical decision-making is inherently safety-critical,…

Computation and Language · Computer Science 2026-04-13 Xiaohan Ren , Chenxiao Fan , Wenyin Ma , Hongliang He , Chongming Gao , Xiaoyan Zhao , Fuli Feng

Multimodal hallucination in multimodal large language models (MLLMs) restricts the correctness of MLLMs. However, multimodal hallucinations are multi-sourced and arise from diverse causes. Existing benchmarks fail to adequately distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Bowen Dong , Minheng Ni , Zitong Huang , Guanglei Yang , Wangmeng Zuo , Lei Zhang

Vision-Language Models (VLMs) are becoming increasingly popular in the medical domain, bridging the gap between medical images and clinical language. Existing VLMs demonstrate an impressive ability to comprehend medical images and text…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Bidur Khanal , Sandesh Pokhrel , Sanjay Bhandari , Ramesh Rana , Nikesh Shrestha , Ram Bahadur Gurung , Cristian Linte , Angus Watson , Yash Raj Shrestha , Binod Bhattarai

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

Computation and Language · Computer Science 2025-03-11 Luyi Jiang , Jiayuan Chen , Lu Lu , Xinwei Peng , Lihao Liu , Junjun He , Jie Xu

Background: The rapid integration of foundation models into clinical practice and public health necessitates a rigorous evaluation of their true clinical reasoning capabilities beyond narrow examination success. Current benchmarks,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Dingyu Wang , Zimu Yuan , Jiajun Liu , Shanggui Liu , Nan Zhou , Tianxing Xu , Di Huang , Dong Jiang

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

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