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The Segment Anything Model (SAM) is a cornerstone of image segmentation, demonstrating exceptional performance across various applications, particularly in autonomous driving and medical imaging, where precise segmentation is crucial.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Xiaoliang Liu , Furao Shen , Jian Zhao

The emergence of large foundation models has propelled significant advances in various domains. The Segment Anything Model (SAM), a leading model for image segmentation, exemplifies these advances, outperforming traditional methods.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Saurabh Yadav , Avi Gupta , Koteswar Rao Jerripothula

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, researchers have found that SAM may have limited performance on medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yihao Liu , Jiaming Zhang , Andres Diaz-Pinto , Haowei Li , Alejandro Martin-Gomez , Amir Kheradmand , Mehran Armand

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

Medical image segmentation has been traditionally approached by training or fine-tuning the entire model to cater to any new modality or dataset. However, this approach often requires tuning a large number of parameters during training.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Jay N. Paranjape , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

The field of medical image segmentation is challenged by domain generalization (DG) due to domain shifts in clinical datasets. The DG challenge is exacerbated by the scarcity of medical data and privacy concerns. Traditional single-source…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Qiang Qiao , Wenyu Wang , Meixia Qu , Kun Su , Bin Jiang , Qiang Guo

Domain generalization aims to learn a generalizable model from a known source domain for various unknown target domains. It has been studied widely by domain randomization that transfers source images to different styles in spatial space…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Jiaxing Huang , Dayan Guan , Aoran Xiao , Shijian Lu

Recently, the Segment Anything Model (SAM) has demonstrated promising segmentation capabilities in a variety of downstream segmentation tasks. However in the context of universal medical image segmentation there exists a notable performance…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Chao Qin , Jiale Cao , Huazhu Fu , Fahad Shahbaz Khan , Rao Muhammad Anwer

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

The recently introduced Segment Anything Model (SAM) combines a clever architecture and large quantities of training data to obtain remarkable image segmentation capabilities. However, it fails to reproduce such results for…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Tal Shaharabany , Aviad Dahan , Raja Giryes , Lior Wolf

Accurate segmentation of cell nuclei in histopathology images is essential for numerous biomedical research and clinical applications. However, existing cell nucleus segmentation methods only consider a single dataset (i.e., primary…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Jiahe Qian , Yaoyu Fang , Jinkui Hao , Bo Zhou

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Due to the inherent flexibility of prompting, foundation models have emerged as the predominant force in the fields of natural language processing and computer vision. The recent introduction of the Segment Anything Model (SAM) signifies a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Yichi Zhang , Zhenrong Shen , Rushi Jiao

Automated polyp segmentation is essential for early diagnosis of colorectal cancer, yet developing robust models remains challenging due to limited annotated data and significant performance degradation under domain shift. Although…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Haoran Xi , Chen Liu , Xiaolin Li

The universality of deep neural networks across different modalities and their generalization capabilities to unseen domains play an essential role in medical image segmentation. The recent segment anything model (SAM) has demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Qing Xu , Jiaxuan Li , Xiangjian He , Chenxin Li , Fiseha B. Tesem , Wenting Duan , Zhen Chen , Rong Qu , Jonathan M. Garibaldi , Chang Wen Chen

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

We have witnessed remarkable progress in foundation models in vision tasks. Currently, several recent works have utilized the segmenting anything model (SAM) to boost the segmentation performance in medical images, where most of them focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Haoran Wang , Lian Huai , Wenbin Li , Lei Qi , Xingqun Jiang , Yinghuan Shi

Segment Anything Model (SAM) has revolutionized the way of segmentation. However, SAM's performance may decline when applied to tasks involving domains that differ from natural images. Nonetheless, by employing fine-tuning techniques, SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Lin Wang , Xiufen Ye , Liqiang Zhu , Weijie Wu , Jianguo Zhang , Huiming Xing , Chao Hu