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Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Recent advances in medical large language models have explored Test-Time Reinforcement Learning (TTRL) to enhance reasoning. However, standard TTRL often relies on majority voting (MV) as a heuristic supervision signal, which can be…

Machine Learning · Computer Science 2026-03-11 Kailong Fan , Anqi Pu , Yichen Wu , Wanhua Li , Yicong Li , Hanspeter Pfister , Huafeng Liu , Xiang Li , Quanzheng Li , Ning Guo

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

Machine Learning · Computer Science 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

In safe offline reinforcement learning (RL), the objective is to develop a policy that maximizes cumulative rewards while strictly adhering to safety constraints, utilizing only offline data. Traditional methods often face difficulties in…

Machine Learning · Computer Science 2026-02-11 Prajwal Koirala , Zhanhong Jiang , Soumik Sarkar , Cody Fleming

Health-aware control (HAC) has emerged as one of the domains where control synthesis is sought based upon the failure prognostics of system/component or the Remaining Useful Life (RUL) predictions of critical components. The fact that…

Artificial Intelligence · Computer Science 2020-10-20 Mayank Shekhar Jha , Philippe Weber , Didier Theilliol , Jean-Christophe Ponsart , Didier Maquin

Standard reinforcement learning (RL) aims to find an optimal policy that identifies the best action for each state. However, in healthcare settings, many actions may be near-equivalent with respect to the reward (e.g., survival). We…

Machine Learning · Computer Science 2020-07-27 Shengpu Tang , Aditya Modi , Michael W. Sjoding , Jenna Wiens

Despite the broad application of deep reinforcement learning (RL), transferring and adapting the policy to unseen but similar environments is still a significant challenge. Recently, the language-conditioned policy is proposed to facilitate…

Machine Learning · Computer Science 2023-03-10 Shaohui Peng , Xing Hu , Rui Zhang , Jiaming Guo , Qi Yi , Ruizhi Chen , Zidong Du , Ling Li , Qi Guo , Yunji Chen

We propose a Reinforcement Learning (RL) based control design framework for handling complex tasks. The approach extends the concept of Reward Machines (RM) with Signal Temporal Logic (STL) formulas that can be used for event generation.…

Artificial Intelligence · Computer Science 2026-04-17 Ana María Gómez Ruiz , Thao Dang , Alexandre Donzé

Constraint handling plays a key role in solving realistic complex optimization problems. Though intensively discussed in the last few decades, existing constraint handling techniques predominantly rely on human experts' designs, which more…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Qianhao Zhu , Sijie Ma , Zeyuan Ma , Hongshu Guo , Yue-Jiao Gong

Personalized decision systems in healthcare and behavioral support often rely on static rule-based or engagement-maximizing heuristics that overlook users' emotional context and ethical constraints. Such approaches risk recommending…

Machine Learning · Computer Science 2025-11-14 Garapati Keerthana , Manik Gupta

Reinforcement learning (RL) has enhanced the capabilities of large language models (LLMs) through reward-driven training. Nevertheless, this process can introduce excessively long responses, inflating inference latency and computational…

Machine Learning · Computer Science 2026-02-17 Chang Liu , Yiran Zhao , Lawrence Liu , Yaoqi Ye , Csaba Szepesvári , Lin F. Yang

Reinforcement learning is able to solve complex sequential decision-making tasks but is currently limited by sample efficiency and required computation. To improve sample efficiency, recent work focuses on model-based RL which interleaves…

Machine Learning · Computer Science 2023-06-19 Yi Zhao , Wenshuai Zhao , Rinu Boney , Juho Kannala , Joni Pajarinen

Safe reinforcement learning (RL) is a standard paradigm for safety-critical decision making. However, real-world safety constraints can be complex, subjective, and even hard to explicitly specify. Existing works on constraint inference rely…

Machine Learning · Computer Science 2026-05-25 Chenglin Li , Grant Ruan , Hua Geng

The rapid increase in the percentage of chronic disease patients along with the recent pandemic pose immediate threats on healthcare expenditure and elevate causes of death. This calls for transforming healthcare systems away from…

Machine Learning · Computer Science 2021-08-10 Alaa Awad Abdellatif , Naram Mhaisen , Zina Chkirbene , Amr Mohamed , Aiman Erbad , Mohsen Guizani

Reinforcement Learning (RL) faces significant challenges in adaptive healthcare interventions, such as dementia care, where data is scarce, decisions require interpretability, and underlying patient-state dynamic are complex and causal in…

Robotics · Computer Science 2025-12-02 Wenzheng Zhao , Ran Zhang , Ruth Palan Lopez , Shu-Fen Wung , Fengpei Yuan

We propose an automata-theoretic approach for reinforcement learning (RL) under complex spatio-temporal constraints with time windows. The problem is formulated using a Markov decision process under a bounded temporal logic constraint.…

Artificial Intelligence · Computer Science 2023-08-01 Xiaoshan Lin , Abbasali Koochakzadeh , Yasin Yazicioglu , Derya Aksaray

The complexity of designing reward functions has been a major obstacle to the wide application of deep reinforcement learning (RL) techniques. Describing an agent's desired behaviors and properties can be difficult, even for experts. A new…

Machine Learning · Computer Science 2024-05-09 Wanqi Xue , Bo An , Shuicheng Yan , Zhongwen Xu

A reinforcement learning (RL) control policy could fail in a new/perturbed environment that is different from the training environment, due to the presence of dynamic variations. For controlling systems with continuous state and action…

Robotics · Computer Science 2022-08-31 Y. Cheng , P. Zhao , F. Wang , D. J. Block , N. Hovakimyan

Reinforcement learning (RL) depends critically on the choice of reward functions used to capture the de- sired behavior and constraints of a robot. Usually, these are handcrafted by a expert designer and represent heuristics for relatively…

Artificial Intelligence · Computer Science 2017-03-03 Xiao Li , Cristian-Ioan Vasile , Calin Belta

Reinforcement learning (RL) has the potential to significantly improve clinical decision making. However, treatment policies learned via RL from observational data are sensitive to subtle choices in study design. We highlight a simple…

Machine Learning · Computer Science 2020-12-23 Christina X. Ji , Michael Oberst , Sanjat Kanjilal , David Sontag