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Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

Large language models have demonstrated remarkable performance in a wide range of medical benchmarks. Yet underneath the seemingly promising results lie salient growth areas, especially in cutting-edge frontiers such as multimodal…

Medical dialogue systems have attracted significant attention for their potential to act as medical assistants. Enabling these medical systems to emulate clinicians' diagnostic reasoning process has been the long-standing research focus.…

Computation and Language · Computer Science 2024-06-21 Kaishuai Xu , Yi Cheng , Wenjun Hou , Qiaoyu Tan , Wenjie Li

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

Machine Learning · Computer Science 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

Translating machine learning (ML) models effectively to clinical practice requires establishing clinicians' trust. Explainability, or the ability of an ML model to justify its outcomes and assist clinicians in rationalizing the model…

Machine Learning · Computer Science 2019-08-08 Sana Tonekaboni , Shalmali Joshi , Melissa D McCradden , Anna Goldenberg

Causal machine learning (CML) has experienced increasing popularity in healthcare. Beyond the inherent capabilities of adding domain knowledge into learning systems, CML provides a complete toolset for investigating how a system would react…

Machine Learning · Computer Science 2022-06-01 Pedro Sanchez , Jeremy P. Voisey , Tian Xia , Hannah I. Watson , Alison Q. ONeil , Sotirios A. Tsaftaris

Artificial intelligence (AI) is expected to revolutionize the practice of medicine. Recent advancements in the field of deep learning have demonstrated success in a variety of clinical tasks: detecting diabetic retinopathy from images,…

Machine Learning · Computer Science 2025-04-04 Joshua Hatherley

AI-driven medical predictions with trustworthy confidence are essential for ensuring the responsible use of AI in healthcare applications. The growing capabilities of AI raise questions about their trustworthiness in healthcare,…

Machine Learning · Computer Science 2025-02-04 Ubaid Azam , Imran Razzak , Shelly Vishwakarma , Hakim Hacid , Dell Zhang , Shoaib Jameel

Artificial Intelligence (AI) systems are now an integral part of multiple industries. In clinical research, AI supports automated adverse event detection in clinical trials, patient eligibility screening for protocol enrollment, and data…

Artificial Intelligence · Computer Science 2025-12-10 Laxmiraju Kandikatla , Branislav Radeljic

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Deductive formalisms have been strongly developed in recent years; among them, Answer Set Programming (ASP) gained some momentum, and has been lately fruitfully employed in many real-world scenarios. Nonetheless, in spite of a large number…

Medicine and deep learning-based artificial intelligence (AI) engineering represent two distinct fields each with decades of published history. With such history comes a set of terminology that has a specific way in which it is applied.…

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Artificial intelligence in medicine is built to serve the average patient. By minimizing error across large datasets, most systems deliver strong aggregate accuracy yet falter at the margins: patients with rare variants, multimorbidity, or…

Artificial Intelligence · Computer Science 2025-10-29 Pedram Fard , Alaleh Azhir , Neguine Rezaii , Jiazi Tian , Hossein Estiri

We present Doctorina MedBench, a comprehensive evaluation framework for agent-based medical AI based on the simulation of realistic physician-patient interactions. Unlike traditional medical benchmarks that rely on solving standardized test…

Computation and Language · Computer Science 2026-03-30 Anna Kozlova , Stanislau Salavei , Pavel Satalkin , Hanna Plotnitskaya , Sergey Parfenyuk

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

This study introduces a transformative framework for medical education by integrating semi-structured data with Large Language Models (LLMs), primarily OpenAIs ChatGPT3.5, to automate the creation of medical simulation scenarios.…

Computation and Language · Computer Science 2024-05-07 Scott Sumpter

Machine learning (ML) models are increasingly being used in application domains that often involve working together with human experts. In this context, it can be advantageous to defer certain instances to a single human expert when they…

Artificial Intelligence · Computer Science 2022-06-17 Patrick Hemmer , Sebastian Schellhammer , Michael Vössing , Johannes Jakubik , Gerhard Satzger

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang
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