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Computational biomarkers (CBs) are histopathology-derived patterns extracted from hematoxylin-eosin (H&E) whole-slide images (WSIs) using artificial intelligence (AI) to predict therapeutic response or prognosis. Recently, slide-level…

Uncertainty quantification (UQ) methods for large language models are predominantly designed by hand based on domain knowledge and heuristics, limiting their scalability and generality. We apply LLM-powered evolutionary search to…

Computation and Language · Computer Science 2026-04-07 Mikhail Seleznyov , Daniil Korbut , Viktor Moskvoretskii , Oleg Somov , Alexander Panchenko , Elena Tutubalina

The ACM Lifelog Search Challenge (LSC) is a venue that welcomes and compares systems that support the exploration of lifelog data, and in particular the retrieval of specific information, through an interactive competition format. This…

Kernel survival analysis models estimate individual survival distributions with the help of a kernel function, which measures the similarity between any two data points. Such a kernel function can be learned using deep kernel survival…

Machine Learning · Computer Science 2025-02-18 George H. Chen

Objective To develop soft prompt-based learning algorithms for large language models (LLMs), examine the shape of prompts, prompt-tuning using frozen/unfrozen LLMs, transfer learning, and few-shot learning abilities. Methods We developed a…

Computation and Language · Computer Science 2024-04-16 Cheng Peng , Xi Yang , Kaleb E Smith , Zehao Yu , Aokun Chen , Jiang Bian , Yonghui Wu

This study investigates the performance of the DeepSeek R1 language model on 30 challenging mathematical problems derived from the MATH dataset, problems that previously proved unsolvable by other models under time constraints. Unlike prior…

Machine Learning · Computer Science 2025-01-31 Evgenii Evstafev

We compare Evolutionary Algorithms with Minima Hopping for global optimization in the field of cluster structure prediction. We introduce a new {\em average offspring} recombination operator and compare it with previously used operators.…

Other Condensed Matter · Physics 2009-11-13 Sandro E. Schoenborn , Stefan Goedecker , Shantanu Roy , Artem R. Oganov

Representing, comparing, and measuring the distance between probability distributions is a key task in computational statistics and machine learning. The choice of representation and the associated distance determine properties of the…

Machine Learning · Statistics 2026-02-26 Masha Naslidnyk

The Efficient SMT-Based Context-Bounded Model Checker (ESBMC) has grown from a research prototype for verifying embedded ANSI-C software into one of the most versatile and industrially capable formal verification platforms available today.…

Software Engineering · Computer Science 2026-05-27 Pierre Dantas , Lucas Cordeiro , Waldir Junior

The complexity of modern bioinformatics analysis has created a critical gap between data generation and developing scientific insights. While large language models (LLMs) have shown promise in scientific reasoning, they remain fundamentally…

Artificial Intelligence · Computer Science 2025-10-01 Orion Li , Vinayak Agarwal , Summer Zhou , Ashwin Gopinath , Timothy Kassis

Geometric deep learning (GDL) has gained significant attention in scientific fields, for its proficiency in modeling data with intricate geometric structures. However, very few works have delved into its capability of tackling the…

Machine Learning · Computer Science 2024-11-21 Deyu Zou , Shikun Liu , Siqi Miao , Victor Fung , Shiyu Chang , Pan Li

Sample-efficient machine learning (SEML) has been widely applied to find optimal latency and power tradeoffs for configurable computer systems. Instead of randomly sampling from the configuration space, SEML reduces the search cost by…

Machine Learning · Computer Science 2022-04-12 Yi Ding , Alex Renda , Ahsan Pervaiz , Michael Carbin , Henry Hoffmann

The LASSO-Clip-EN (LCEN) algorithm was previously introduced for nonlinear, interpretable feature selection and machine learning. However, its design and use was limited to regression tasks. In this work, we create a modified version of the…

Machine Learning · Computer Science 2026-04-24 Pedro Seber , Richard D. Braatz

As large language models (LLMs) advance, the ultimate vision for their role in science is emerging: we could build an AI collaborator to effectively assist human beings throughout the entire scientific research process. We refer to this…

In recent years, two competitive time series classification models, namely, ROCKET and MINIROCKET, have garnered considerable attention due to their low training cost and high accuracy. However, they rely on a large number of random 1-D…

Machine Learning · Computer Science 2024-07-26 Shaowu Chen , Weize Sun , Lei Huang , Xiaopeng Li , Qingyuan Wang , Deepu John

Large language models can now generate substantial code and draft research text, but research-software projects require more than either artifact alone. The mathematical thesis, executable system, benchmark surface, and public claims must…

Software Engineering · Computer Science 2026-05-04 Halley Young , Nikolaj Björner

The rapid advancement of large language models has opened new avenues for automating complex problem-solving tasks such as algorithmic coding and competitive programming. This paper introduces a novel evaluation technique, LLM-ProS, to…

Computation and Language · Computer Science 2026-03-03 Md Sifat Hossain , Anika Tabassum , Md. Fahim Arefin , Tarannum Shaila Zaman

While Large Language Models (LLMs) can accelerate text-heavy tasks in alternative investment due diligence, a gap remains in their ability to accurately extract and reason over structured tabular data from complex financial spreadsheets.…

Artificial Intelligence · Computer Science 2026-03-10 Jan Ravnik , Matjaž Ličen , Felix Bührmann , Bithiah Yuan , Felix Stinson , Tanvi Singh

Synthetic survey data generated by large language models (LLMs) suffers from a fundamental circularity: the same model family that generates text responses also maps them to numerical scales. We calibrate and validate Semantic Similarity…

Physics and Society · Physics 2026-02-24 Eduardo Vera Pichardo

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

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