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Depression is a widespread mental disorder that affects millions worldwide. While automated depression assessment shows promise, most studies rely on limited or non-clinically validated data, and often prioritize complex model design over…

Computation and Language · Computer Science 2025-08-07 Zhuang Chen , Guanqun Bi , Wen Zhang , Jiawei Hu , Aoyun Wang , Xiyao Xiao , Kun Feng , Minlie Huang

Large Language Models (LLMs) equipped with external tools have demonstrated enhanced performance on complex reasoning tasks. The widespread adoption of this tool-augmented reasoning is hindered by the scarcity of domain-specific tools. For…

Computation and Language · Computer Science 2025-10-10 Murong Yue , Zhiwei Liu , Liangwei Yang , Jianguo Zhang , Zuxin Liu , Haolin Chen , Ziyu Yao , Silvio Savarese , Caiming Xiong , Shelby Heinecke , Huan Wang

It is becoming increasingly emphasis on the importance of LLM participating in clinical diagnosis decision-making. However, the low specialization refers to that current medical LLMs can not provide specific medical advice, which are more…

Computation and Language · Computer Science 2023-12-06 Binbin Li , Tianxin Meng , Xiaoming Shi , Jie Zhai , Tong Ruan

Healthcare providers usually record detailed notes of the clinical care delivered to each patient for clinical, research, and billing purposes. Due to the unstructured nature of these narratives, providers employ dedicated staff to assign…

Computation and Language · Computer Science 2022-08-03 Chufan Gao , Mononito Goswami , Jieshi Chen , Artur Dubrawski

Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking…

Coding of unstructured clinical free-text to produce interoperable structured data is essential to improve direct care, support clinical communication and to enable clinical research.However, manual clinical coding is difficult and time…

Code reasoning tasks are becoming prevalent in large language model (LLM) assessments. Yet, there is a dearth of studies on the impact of real-world complexities on code reasoning, e.g., inter- or intra-procedural dependencies, API calls,…

Software Engineering · Computer Science 2026-04-27 Changshu Liu , Alireza Ghazanfari , Yang Chen , Reyhaneh Jabbarvand

Clinical language processing has received a lot of attention in recent years, resulting in new models or methods for disease phenotyping, mortality prediction, and other tasks. Unfortunately, many of these approaches are tested under…

Computation and Language · Computer Science 2022-09-30 Travis R. Goodwin , Dina Demner-Fushman

Clinical coding is crucial for healthcare billing and data analysis. Manual clinical coding is labour-intensive and error-prone, which has motivated research towards full automation of the process. However, our analysis, based on US English…

Computation and Language · Computer Science 2025-06-19 Yidong Gan , Maciej Rybinski , Ben Hachey , Jonathan K. Kummerfeld

The application of Large Language Models (LLMs) in healthcare is expanding rapidly, with one potential use case being the translation of formal medical reports into patient-legible equivalents. Currently, LLM outputs often need to be edited…

Multiagent Systems · Computer Science 2024-08-06 Malavikha Sudarshan , Sophie Shih , Estella Yee , Alina Yang , John Zou , Cathy Chen , Quan Zhou , Leon Chen , Chinmay Singhal , George Shih

While LLM-Based agents, which use external tools to solve complex problems, have made significant progress, benchmarking their ability is challenging, thereby hindering a clear understanding of their limitations. In this paper, we propose…

Computation and Language · Computer Science 2024-11-07 Chuyu Zhang , Songyang Zhang , Yingfan Hu , Haowen Shen , Kuikun Liu , Zerun Ma , Fengzhe Zhou , Wenwei Zhang , Xuming He , Dahua Lin , Kai Chen

Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Computation and Language · Computer Science 2025-09-08 Maya Kruse , Shiyue Hu , Nicholas Derby , Yifu Wu , Samantha Stonbraker , Bingsheng Yao , Dakuo Wang , Elizabeth Goldberg , Yanjun Gao

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Large language models (LLMs) are increasingly explored for their reasoning capabilities, yet their ability to perform structured, constraint-based optimization from natural language remains insufficiently understood. This study evaluates…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Aasish Kumar Sharma , Julian Kunkel

Large language models (LLMs) excel at natural language tasks but remain brittle in domains requiring precise logical and symbolic reasoning. Chaotic dynamical systems provide an especially demanding test because chaos is deterministic yet…

Artificial Intelligence · Computer Science 2026-02-13 Noel Thomas

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and…

Computation and Language · Computer Science 2024-06-06 Xiangru Tang , Anni Zou , Zhuosheng Zhang , Ziming Li , Yilun Zhao , Xingyao Zhang , Arman Cohan , Mark Gerstein

The field of medical diagnosis has undergone a significant transformation with the advent of large language models (LLMs), yet the challenges of interpretability within these models remain largely unaddressed. This study introduces…

Computation and Language · Computer Science 2024-09-17 Junying Chen , Chi Gui , Anningzhe Gao , Ke Ji , Xidong Wang , Xiang Wan , Benyou Wang

As large language models (LLMs) enter the medical domain, most benchmarks evaluate them on question answering or descriptive reasoning, overlooking quantitative reasoning critical to clinical decision-making. Existing datasets like…

Computation and Language · Computer Science 2025-11-03 Kangkun Mao , Jinru Ding , Jiayuan Chen , Mouxiao Bian , Ruiyao Chen , Xinwei Peng , Sijie Ren , Linyang Li , Jie Xu

Joint logical-numerical reasoning remains a major challenge for language models, yet existing datasets rely on fixed rule sets and offer limited control over task complexity, constraining their generalizability for evaluation and training.…

Computation and Language · Computer Science 2025-10-14 Yiwei Liu , Yucheng Li , Xiao Li , Gong Cheng

Critiques are important for enhancing the performance of Large Language Models (LLMs), enabling both self-improvement and constructive feedback for others by identifying flaws and suggesting improvements. However, evaluating the critique…

Computation and Language · Computer Science 2025-01-27 Zhengyang Tang , Ziniu Li , Zhenyang Xiao , Tian Ding , Ruoyu Sun , Benyou Wang , Dayiheng Liu , Fei Huang , Tianyu Liu , Bowen Yu , Junyang Lin