Related papers: Rethinking Evaluation of Multiple Sclerosis (MS) L…

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that results in focal injury to the grey and white matter. The presence of white matter lesions biases morphometric analyses such as…

Despite recent improvements in medical image segmentation, the ability to generalize across imaging contrasts remains an open issue. To tackle this challenge, we implement Feature-wise Linear Modulation (FiLM) to leverage physics knowledge…

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

The timely identification of significant memory concern (SMC) is crucial for proactive cognitive health management, especially in an aging population. Detecting SMC early enables timely intervention and personalized care, potentially…

Brain stroke has become a significant burden on global health and thus we need remedies and prevention strategies to overcome this challenge. For this, the immediate identification of stroke and risk stratification is the primary task for…

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Stereotactic radiosurgery (SRS), which delivers high doses of irradiation in a single or few shots to small targets, has been a standard of care for brain metastases. While very effective, SRS currently requires manually intensive…

Accurate lesion-level segmentation on MRI is critical for multiple sclerosis (MS) diagnosis, prognosis, and disease monitoring. However, current evaluation practices largely rely on semantic segmentation post-processed with connected…

Schizophrenia is a severe yet treatable mental disorder, it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms, therefore there is a need for…

Deep neural networks have demonstrated exceptional efficacy in stroke lesion segmentation. However, the delineation of small lesions, critical for stroke diagnosis, remains a challenge. In this study, we propose two straightforward yet…

The field of computer vision is undergoing a paradigm shift toward large-scale foundation model pre-training via self-supervised learning (SSL). Leveraging large volumes of unlabeled brain MRI data, such models can learn anatomical priors…

Lesion segmentation is an important problem in computer-assisted diagnosis that remains challenging due to the prevalence of low contrast, irregular boundaries that are unamenable to shape priors. We introduce Deep Active Lesion…

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

This research proposal discusses two challenges in the field of medical image analysis: the multi-parametric investigation on microstructural and macrostructural characteristics of the cervical spinal cord and deep learning-based medical…

Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive…

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Research in Multiple Sclerosis (MS) has recently focused on extracting knowledge from real-world clinical data sources. This type of data is more abundant than data produced during clinical trials and potentially more informative about…

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions. At each visit, a contrast agent is administered…

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…