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Large health surveys increasingly collect high-dimensional functional data from wearable devices, and function on scalar regression (FoSR) is often used to quantify the relationship between these functional outcomes and scalar covariates…

Methodology · Statistics 2025-11-10 Lily Koffman , Sunan Gao , Xinkai Zhou , Andrew Leroux , Ciprian Crainiceanu , John Muschelli

The regression of principal component scores (RPCS) on covariates is a widely used analytic approach to detect and test for associations between functional measurements and study participant characteristics. Here we show that: (1) RPCS…

Methodology · Statistics 2026-05-26 Yu Lu , Nidhi Pai , Erjia Cui , Ciprian Crainiceanu

Physical activity (PA) is an important risk factor for many health outcomes. Wearable-devices such as accelerometers are increasingly used in biomedical studies to understand the associations between PA and health outcomes. Statistical…

Methodology · Statistics 2021-12-08 Sneha Jadhav , Carmen D. Tekwe , Yuanyuan Luan

Quantile regression is useful for characterizing the conditional distribution of a response variable and understanding heterogeneity in the covariate effects at different quantiles. The rise of high-dimensional physiological data in…

Methodology · Statistics 2026-03-25 Yuanzhen Yue , Stella Self , Yichao Wu , Jiajia Zhang , Rahul Ghosal

We propose a computationally efficient inferential procedure for longitudinal function-on-function regression. The method follows a marginal three-step approach: (1) fit massive pointwise longitudinal scalar-on-function regression models,…

Methodology · Statistics 2026-05-04 Leif Verace , Siobhan McMahon , Erjia Cui

Functional data contains two components: shape (or amplitude) and phase. This paper focuses on a branch of functional data analysis (FDA), namely Shape-Based FDA, that isolates and focuses on shapes of functions. Specifically, this paper…

Methodology · Statistics 2024-11-26 Sayan Bhadra , Anuj Srivastava

Recent technological developments have enabled us to collect complex and high-dimensional data in many scientific fields, such as population health, meteorology, econometrics, geology, and psychology. It is common to encounter such datasets…

Methodology · Statistics 2020-03-16 Ufuk Beyaztas , Han Lin Shang

Physical activity (PA) is significantly associated with many health outcomes. The wide usage of wearable accelerometer-based activity trackers in recent years has provided a unique opportunity for in-depth research on PA and its relations…

Physical activity (PA) plays an important role in maintaining and improving health. Daily steps have been a key PA measure that is easily accessible with common wearable devices. However, methods are lacking to recommend a personalized…

Applications · Statistics 2026-05-20 Gefei Lin , Rui Miao , Jennifer Sacheck , Xiaoke Zhang

Wearable devices such as the ActiGraph are now commonly used in health studies to monitor or track physical activity. This trend aligns well with the growing need to accurately assess the effects of physical activity on health outcomes such…

Methodology · Statistics 2022-11-10 Roger S. Zoh , Yuanyuan Luan , Carmen Tekwe

We present a multivariate functional mixed effects model for kinematic data from a large number of recreational runners. The runners' sagittal plane hip and knee angles are modelled jointly as a bivariate function with random effects…

We propose an extensive framework for additive regression models for correlated functional responses, allowing for multiple partially nested or crossed functional random effects with flexible correlation structures for, e.g., spatial,…

Methodology · Statistics 2013-11-26 Fabian Scheipl , Ana-Maria Staicu , Sonja Greven

Shape restrictions on functional regression coefficients such as non-negativity, monotonicity, convexity or concavity are often available in the form of a prior knowledge or required to maintain a structural consistency in functional…

Methodology · Statistics 2022-09-13 Rahul Ghosal , Sujit Ghosh , Jacek Urbanek , Jennifer A. Schrack , Vadim Zipunnikov

Functional principal component analysis has been shown to be invaluable for revealing variation modes of longitudinal outcomes, which serves as important building blocks for forecasting and model building. Decades of research have advanced…

Methodology · Statistics 2024-10-07 Peijun Sang , Dehan Kong , Shu Yang

To optimize mobile health interventions and advance domain knowledge on intervention design, it is critical to understand how the intervention effect varies over time and with contextual information. This study aims to assess how a push…

Applications · Statistics 2024-10-22 Jiaxin Yu , Tianchen Qian

Wearable devices are often used in clinical and epidemiological studies to monitor physical activity behavior and its influence on health outcomes. These devices are worn over multiple days to record activity patterns, such as step counts…

Methodology · Statistics 2025-11-14 Heyang Ji , Lan Xue , Ufuk Beyaztas , Roger S. Zoh , Jeff Goldsmith , Mark E. Benden , Carmen D. Tekwe

As one of the most powerful tools for examining the association between functional covariates and a response, the functional regression model has been widely adopted in various interdisciplinary studies. Usually, a limited number of…

Methodology · Statistics 2025-01-07 Hanteng Ma , Ziliang Shen , Xingdong Feng , Xin Liu

Modelling a large collection of functional time series arises in a broad spectral of real applications. Under such a scenario, not only the number of functional variables can be diverging with, or even larger than the number of temporally…

Statistics Theory · Mathematics 2021-09-01 Shaojun Guo , Xinghao Qiao

Functional data is a powerful tool for capturing and analyzing complex patterns and relationships in a variety of fields, allowing for more precise modeling, visualization, and decision-making. For example, in healthcare, functional data…

Methodology · Statistics 2023-04-26 Xiyuan Gao , Jiayi Wang , Guanyu Hu , Jianguo Sun

Functional variables are often used as predictors in regression problems. A commonly-used parametric approach, called {\it scalar-on-function regression}, uses the $\ltwo$ inner product to map functional predictors into scalar responses.…

Methodology · Statistics 2020-06-02 Kyungmin Ahn , J. Derek Tucker , Wei Wu , Anuj Srivastava
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