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The large-scale pre-trained vision language models (VLM) have shown remarkable domain transfer capability on natural images. However, it remains unknown whether this capability can also apply to the medical image domain. This paper…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Ziyuan Qin , Huahui Yi , Qicheng Lao , Kang Li

The task of medical image recognition is notably complicated by the presence of varied and multiple pathological indications, presenting a unique challenge in multi-label classification with unseen labels. This complexity underlines the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-16 Yaoqin Ye , Junjie Zhang , Hongwei Shi

Medical vision language pre-training (VLP) has emerged as a frontier of research, enabling zero-shot pathological recognition by comparing the query image with the textual descriptions for each disease. Due to the complex semantics of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Vu Minh Hieu Phan , Yutong Xie , Yuankai Qi , Lingqiao Liu , Liyang Liu , Bowen Zhang , Zhibin Liao , Qi Wu , Minh-Son To , Johan W. Verjans

Pretrained biomedical vision-language models (VLMs) such as BioMedCLIP perform well on average but often degrade on challenging modalities where inter-class margins are small and acquisition-specific variations are pronounced, especially…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Mainak Singha , Tanisha Gupta , Ankit Jha , Muhammad Haris Khan , Sayantani Ghosh , Biplab Banerjee

Vision-language models (VLMs) can couple visual perception with open-ended clinical reasoning, making them attractive for computational histopathology. However, fine-tuning billions of parameters on scarce, expert-annotated pathology data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Franciskus Xaverius Erick , Johanna Paula Müller , Bernhard Kainz

Recent advancements in vision-language models (VLMs), such as CLIP, have demonstrated substantial success in self-supervised representation learning for vision tasks. However, effectively adapting VLMs to downstream applications remains…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Vision-language models (VLMs) have gained significant attention in computational pathology due to their multimodal learning capabilities that enhance big-data analytics of giga-pixel whole slide image (WSI). However, their sensitivity to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-02 Vasudev Sharma , Ahmed Alagha , Abdelhakim Khellaf , Vincent Quoc-Huy Trinh , Mahdi S. Hosseini

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

Vision-Language Models (VLMs) have rapidly advanced alongside Large Language Models (LLMs). This study evaluates the capabilities of prominent generative VLMs, such as GPT-4.1 and Gemini 2.5 Pro, accessed via APIs, for histopathology image…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Samarth Singhal , Sandeep Singhal

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

Vision-Language Models (VLMs), such as CLIP, have significantly advanced zero-shot image recognition. However, their performance remains limited by suboptimal prompt engineering and poor adaptability to target classes. While recent methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hui Liu , Kecheng Chen , Jialiang Wang , Xianming Liu , Wenya Wang , Haoliang Li

Integrating image and text data through multi-modal learning has emerged as a new approach in medical imaging research, following its successful deployment in computer vision. While considerable efforts have been dedicated to establishing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Fereshteh Shakeri , Yunshi Huang , Julio Silva-Rodríguez , Houda Bahig , An Tang , Jose Dolz , Ismail Ben Ayed

Visual reasoning is crucial for understanding complex multimodal data and advancing Artificial General Intelligence. Existing methods enhance the reasoning capability of Multimodal Large Language Models (MLLMs) through Reinforcement…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Chaoyang Wang , Zeyu Zhang , Meng Meng , Xu Zhou , Haiyun Jiang

Fine-tuned vision-language models (VLMs) often capture spurious correlations between image features and textual attributes, resulting in degraded zero-shot performance at test time. Existing approaches for addressing spurious correlations…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Maya Varma , Jean-Benoit Delbrouck , Zhihong Chen , Akshay Chaudhari , Curtis Langlotz

Medical Vision-Language Models (Med-VLMs) have demonstrated remarkable performance across diverse medical imaging tasks by leveraging large-scale image-text pretraining. However, their confidence calibration is largely unexplored, and so…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Abhishek Basu , Fahad Shamshad , Ashshak Sharifdeen , Karthik Nandakumar , Muhammad Haris Khan

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Devavrat Tomar , Guillaume Vray , Dwarikanath Mahapatra , Sudipta Roy , Jean-Philippe Thiran , Behzad Bozorgtabar

Recent advances in multimodal learning has resulted in powerful vision-language models, whose representations are generalizable across a variety of downstream tasks. Recently, their generalization ability has been further extended by…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Koustava Goswami , Srikrishna Karanam , Prateksha Udhayanan , K J Joseph , Balaji Vasan Srinivasan

Medical diagnosis prediction plays a critical role in disease detection and personalized healthcare. While machine learning (ML) models have been widely adopted for this task, their reliance on supervised training limits their ability to…

Artificial Intelligence · Computer Science 2025-07-08 Yuzhang Xie , Hejie Cui , Ziyang Zhang , Jiaying Lu , Kai Shu , Fadi Nahab , Xiao Hu , Carl Yang

Zero-shot anomaly detection (ZSAD) identifies anomalies without needing training samples from the target dataset, essential for scenarios with privacy concerns or limited data. Vision-language models like CLIP show potential in ZSAD but…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Chengyuan Li , Suyang Zhou , Jieping Kong , Lei Qi , Hui Xue