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Quantitative magnetization transfer (qMT) imaging provides myelin-sensitive biomarkers, such as the pool size ratio (PSR), which is valuable for multiple sclerosis (MS) assessment. However, qMT requires specialized 20-30 minute scans. We…
We have developed a novel scanning probe-based methodology to study cell biomechanics. The time dependence of the force exerted by the cell surface on a scanning probe at constant local deformation has been used to extract local…
Diffusion tensor cardiac magnetic resonance (DT-CMR) is a method capable of providing non-invasive measurements of myocardial microstructure. Image registration is essential to correct image shifts due to intra and inter breath-hold motion…
Accurate MR signal simulation, including microvascular structures and water diffusion, is crucial for MRI techniques like fMRI BOLD modeling and MR vascular Fingerprinting (MRF), which use susceptibility effects on MR signals for tissue…
Positron Emission Tomography and Magnetic Resonance Imaging (PET-MRI) systems can obtain functional and anatomical scans. PET suffers from a low signal-to-noise ratio. Meanwhile, the k-space data acquisition process in MRI is…
In astrophysics, turbulent diffusion is often used in place of microphysical diffusion to avoid resolving the small scales. However, we expect this approach to break down when time and length scales of the turbulence become comparable with…
Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…
This paper concerns the fully automatic direct in vivo measurement of active and passive dynamic skeletal muscle states using ultrasound imaging. Despite the long standing medical need (myopathies, neuropathies, pain, injury, ageing),…
Diffusion tensor imaging (DTI) is a widely used method for studying brain white matter development and degeneration. However, standard DTI estimation methods depend on a large number of high-quality measurements. This would require long…
Tissue microstructure has significance as a biomarker, however its accurate inference with diffusion magnetic resonance (MR) is still an open problem. With few exceptions, diffusion weighted (DW) MR models either process diffusion MR data…
Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…
Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…
Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…
Diffusion model-based approaches recently achieved re-markable success in MRI reconstruction, but integration into clinical routine remains challenging due to its time-consuming convergence. This phenomenon is partic-ularly notable when…
Using shear wave elastography, we measure the changes in the wave speed with the stress produced by a striated muscle during isometric voluntary contraction. To isolate the behaviour of an individual muscle from complementary or…
Purpose: To provide a simulation framework for routine neuroimaging test data, which allows for "stress testing" of deep segmentation networks against acquisition shifts that commonly occur in clinical practice for T2 weighted (T2w) fluid…
Magnetic Resonance Imaging (MRI) stands as a powerful modality in clinical diagnosis. However, it is known that MRI faces challenges such as long acquisition time and vulnerability to motion-induced artifacts. Despite the success of many…
Multiexponential T2 (MET2) Relaxometry and Magnetization Transfer (MT) are among the most promising MRI-derived techniques for white matter (WM) characterization. Both techniques are shown to have histologically correlated sensitivity to…
This paper proposes a statistical framework to optimize and evaluate the MR parameter $T_1$ and $T_2$ mapping capabilities for quantitative MRI relaxometry approaches. This analysis explores the intrinsic MR parameter estimate precision per…
Advanced diffusion MRI models are being explored to study the complex microstructure of the brain with higher accuracy. However, these techniques require long acquisition times. Simultaneous multi-slice (SMS) accelerates data acquisition by…