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Related papers: Combined Diffusion-Relaxation MRI to Assess Muscle…

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We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…

Medical Physics · Physics 2024-08-21 Ting Gong , Merlin J. Fair , Kawin Setsompop , Hui Zhang

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by diffuse and focal areas of tissue loss. Conventional MRI techniques such as T1-weighted and T2-weighted scans are generally used in the diagnosis and…

Joint modeling of diffusion and relaxation has seen growing interest due to its potential to provide complementary information about tissue microstructure. For brain white matter, we designed an optimal diffusion-relaxometry MRI protocol…

Diffusion-weighted MRI (DW-MRI) is used to quantitatively characterize the microscopic structure of soft tissue due to the anisotropic diffusion of water in muscle. Applications such as fiber tractography or modeling of tumor spread in soft…

Medical Physics · Physics 2024-06-07 Nadya Shusharina , Xiaofeng Liu , Evangelia Kaza , Miranda Lam , Stephan Maier , Jonghye Woo

Purpose: A combined diffusion-relaxometry MR acquisition and analysis pipeline for in-vivo human placenta, which allows for exploration of coupling between T2* and apparent diffusion coefficient (ADC) measurements in a sub 10 minute scan…

Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Haykel Snoussi , Julien Cohen-Adad , Benoit Combes , Elise Bannier , Slimane Tounekti , Anne Kerbrat , Christian Barillot , Emmanuel Caruyer

The emergence of multiparametric diffusion models combining diffusion and relaxometry measurements provide powerful new ways to explore tissue microstructure with the potential to provide new insights into tissue structure and function.…

Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately…

OBJECTIVES: Quantitative MRI techniques such as T2 and T1$\rho$ mapping are beneficial in evaluating cartilage and meniscus. We aimed to evaluate the MIXTURE (Multi-Interleaved X-prepared Turbo-Spin Echo with IntUitive RElaxometry)…

Modelling the diffusion-relaxation magnetic resonance (MR) signal obtained from multi-parametric sequences has recently gained immense interest in the community due to new techniques significantly reducing data acquisition time. A preferred…

Medical Physics · Physics 2025-01-28 Fabian Bogusz , Tomasz Pieciak

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Diffusion magnetic resonance imaging (dMRI) is a relatively modern technique used to study tissue microstructure in a non-invasive way. Non-Gaussian diffusion representation is related to the restricted diffusion and can provide information…

Signal Processing · Electrical Eng. & Systems 2020-09-17 Tomasz Pieciak , Maryam Afzali , Fabian Bogusz , Aja-Fernández , Derek K. Jones

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Magnetic Resonance Fingerprinting (MRF) enables the simultaneous quantification of multiple properties of biological tissues. It relies on a pseudo-random acquisition and the matching of acquired signal evolutions to a precomputed…

Recently, diffusion models have gained significant attention as a novel set of deep learning-based generative methods. These models attempt to sample data from a Gaussian distribution that adheres to a target distribution, and have been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Chenyan Zhang , Yifei Chen , Zhenxiong Fan , Yiyu Huang , Wenchao Weng , Ruiquan Ge , Dong Zeng , Changmiao Wang

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev

Diffusion functional MRI (dfMRI) is a promising technique to map functional activations by acquiring diffusion-weighed spin-echo images. In previous studies, dfMRI showed higher spatial accuracy at activation mapping compared to classic…

Medical Physics · Physics 2019-08-15 Alberto De Luca , Lara Schlaffke , Jeroen CW Siero , Martijn Froeling , Alexander Leemans

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield
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