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In the age of AI-powered educational (AIED) innovation, evaluating the developmental consequences of novel designs before they are exposed to students has become both essential and challenging. Since such interventions may carry…

Computers and Society · Computer Science 2025-10-13 Jianxiao Jiang , Yu Zhang

Molecular dynamics (MD) simulation techniques are widely used for various natural science applications. Increasingly, machine learning (ML) force field (FF) models begin to replace ab-initio simulations by predicting forces directly from…

Computational Physics · Physics 2023-08-29 Xiang Fu , Zhenghao Wu , Wujie Wang , Tian Xie , Sinan Keten , Rafael Gomez-Bombarelli , Tommi Jaakkola

The development of LLM-based autonomous agents for end-to-end software development represents a significant paradigm shift in software engineering. However, the scientific evaluation of these systems is hampered by significant challenges,…

Software Engineering · Computer Science 2025-11-07 Zhengran Zeng , Yixin Li , Rui Xie , Wei Ye , Shikun Zhang

Molecular Vibe Coding, a paradigm where chemists interact with LLMs to generate executable programs for molecular tasks, has emerged as a flexible alternative to chemical agents with predefined tools, enabling chemists to express…

Computation and Language · Computer Science 2026-05-06 Jiatong Li , Yuxuan Ren , Weida Wang , Changmeng Zheng , Xiao-yong Wei , Qing Li , Yatao Bian

Agentic AI systems have gained significant attention for their ability to autonomously perform complex tasks. However, their reliance on well-prepared tools limits their applicability in the medical domain, which requires to train…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Jinghao Feng , Qiaoyu Zheng , Chaoyi Wu , Ziheng Zhao , Ya Zhang , Yanfeng Wang , Weidi Xie

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Modern Vision-Language Models (VLMs) remain poorly characterized in multi-step visual interactions, particularly in how they integrate perception, memory, and action over long horizons. We introduce VisGym, a gymnasium of 17 environments…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Zirui Wang , Junyi Zhang , Jiaxin Ge , Long Lian , Letian Fu , Lisa Dunlap , Ken Goldberg , XuDong Wang , Ion Stoica , David M. Chan , Sewon Min , Joseph E. Gonzalez

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

MCP standardizes how LLMs interact with external systems, forming the foundation for general agents. However, existing MCP benchmarks remain narrow in scope: they focus on read-heavy tasks or tasks with limited interaction depth, and fail…

This benchmark suite provides a comprehensive evaluation framework for assessing both individual LLMs and multi-agent systems in Real-world planning and scheduling scenarios. The suite encompasses 14 designed planning and scheduling…

Artificial Intelligence · Computer Science 2025-08-06 Longling Geng , Edward Y. Chang

We interact with computers on an everyday basis, be it in everyday life or work, and many aspects of work can be done entirely with access to a computer and the Internet. At the same time, thanks to improvements in large language models…

Generative Agent-Based Models (GABMs) powered by large language models (LLMs) offer promising potential for empirical logistics and supply chain management (LSCM) research by enabling realistic simulation of complex human behaviors. Unlike…

Multiagent Systems · Computer Science 2025-08-29 Vincent E. Castillo

Tool-augmented large language models (LLMs), hereafter LLM agents, leverage external tools to solve diverse tasks and interface with the real world. However, current training practices largely rely on supervised fine-tuning (SFT) over…

Machine Learning · Computer Science 2026-03-18 Weihua Du , Hailei Gong , Zhan Ling , Kang Liu , Lingfeng Shen , Xuesong Yao , Yufei Xu , Dingyuan Shi , Yiming Yang , Jiecao Chen

Graphical user interface (GUI) agents powered by multimodal large language models (MLLMs) have shown greater promise for human-interaction. However, due to the high fine-tuning cost, users often rely on open-source GUI agents or APIs…

Computation and Language · Computer Science 2025-05-26 Pengzhou Cheng , Haowen Hu , Zheng Wu , Zongru Wu , Tianjie Ju , Zhuosheng Zhang , Gongshen Liu

AI coding agents increasingly act directly within software environments, yet existing analyses of their failures rely on benchmark trajectories that miss how developers actually experience misalignment. We present an observational study of…

Software Engineering · Computer Science 2026-05-29 Ningzhi Tang , Chaoran Chen , Gelei Xu , Yiyu Shi , Yu Huang , Collin McMillan , Tao Dong , Toby Jia-Jun Li

Artificial intelligence is increasingly catalyzing scientific automation, with multimodal large language model (MLLM) agents evolving from lab assistants into self-driving lab operators. This transition imposes stringent safety requirements…

Artificial Intelligence · Computer Science 2026-03-13 Qianpu Sun , Xiaowei Chi , Yuhan Rui , Ying Li , Kuangzhi Ge , Jiajun Li , Sirui Han , Shanghang Zhang

LLM-based agent systems are emerging as a new software paradigm and have been widely adopted across diverse domains such as medicine, robotics, and programming. However, maintaining these systems requires substantial effort, as they are…

Artificial Intelligence · Computer Science 2025-10-27 Alfin Wijaya Rahardja , Junwei Liu , Weitong Chen , Zhenpeng Chen , Yiling Lou

Physics-aware symbolic simulation of 3D scenes is critical for robotics, embodied AI, and scientific computing, requiring models to understand natural language descriptions of physical phenomena and translate them into executable simulation…

Robotics · Computer Science 2026-04-28 Tianyidan Xie , Peiyu Wang , Yuyi Qian , Yuxuan Wang , Rui Ma , Ying Tai , Song Wu , Qian Wang , Lanjun Wang , Zili Yi

Coding agents powered by large language models (LLMs) have gained traction for automating code generation through iterative problem-solving with minimal human involvement. Despite the emergence of various frameworks, e.g., LangChain,…

Machine Learning · Computer Science 2025-08-19 Junpeng Wang , Yuzhong Chen , Menghai Pan , Chin-Chia Michael Yeh , Mahashweta Das

Large language models (LLMs) are changing the way researchers interact with code and data in scientific computing. While their ability to generate general-purpose code is well established, their effectiveness in producing scientifically…

Software Engineering · Computer Science 2026-05-25 Ethan Holbrook , Juan C. Verduzco , Alejandro Strachan