English
Related papers

Related papers: MDGYM: Benchmarking AI Agents on Molecular Simulat…

200 papers

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

Current LLM agents are proficient at calling isolated APIs but struggle with the "last mile" of commercial software automation. In real-world scenarios, tools are not independent; they are atomic, interdependent, and prone to environmental…

Artificial Intelligence · Computer Science 2026-05-21 Yuanyang Li , Xue Yang , Longyue Wang , Weihua Luo , Hongyang Chen

With the advent of AI agents, automatic scientific discovery has become a tenable goal. Many recent works scaffold agentic systems that can perform machine learning research, but don't offer a principled way to train such agents -- and…

Artificial Intelligence · Computer Science 2026-03-19 Ziyang Cai , Harkirat Behl

Mathematical modeling is a cornerstone of scientific discovery and engineering practice, enabling the translation of real-world problems into formal systems across domains such as physics, biology, and economics. Unlike mathematical…

Artificial Intelligence · Computer Science 2025-05-21 Fan Liu , Zherui Yang , Cancheng Liu , Tianrui Song , Xiaofeng Gao , Hao Liu

Recent years have witnessed a rapid development of mobile GUI agents powered by large language models (LLMs), which can autonomously execute diverse device-control tasks based on natural language instructions. The increasing accuracy of…

Cryptography and Security · Computer Science 2026-04-15 Guohong Liu , Jialei Ye , Jiacheng Liu , Yuanchun Li , Wei Liu , Pengzhi Gao , Jian Luan , Yunxin Liu

Scientific reasoning inherently demands integrating sophisticated toolkits to navigate domain-specific knowledge. Yet, current benchmarks largely overlook agents' ability to orchestrate tools for such rigorous workflows. To bridge this gap,…

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Computation and Language · Computer Science 2026-02-11 Pengcheng Qiu , Chaoyi Wu , Junwei Liu , Qiaoyu Zheng , Yusheng Liao , Haowen Wang , Yun Yue , Qianrui Fan , Shuai Zhen , Jian Wang , Jinjie Gu , Yanfeng Wang , Ya Zhang , Weidi Xie

The BrowserGym ecosystem addresses the growing need for efficient evaluation and benchmarking of web agents, particularly those leveraging automation and Large Language Models (LLMs). Many existing benchmarks suffer from fragmentation and…

AI agents that autonomously interact with external tools and environments have shown great promise across real-world applications. However, their reliance on external data exposes them to serious indirect prompt injection attacks, where…

Cryptography and Security · Computer Science 2026-05-08 Hao Li , Ruoyao Wen , Shanghao Shi , Ning Zhang , Yevgeniy Vorobeychik , Chaowei Xiao

Large language model (LLM)-based agents are increasingly used to perform complex, multi-step workflows in regulated settings such as compliance and due diligence. However, many agentic architectures rely primarily on prompt engineering of a…

Artificial Intelligence · Computer Science 2026-02-03 Ananya Joshi , Michael Rudow

Molecular dynamics (MD) simulations employing classical force fields constitute the cornerstone of contemporary atomistic modeling in chemistry, biology, and materials science. However, the predictive power of these simulations is only as…

Chemical Physics · Physics 2018-09-26 Stefan Chmiela , Huziel E. Sauceda , Klaus-Robert Müller , Alexandre Tkatchenko

The increasing deployment of Large Language Model (LLM) agents for complex software engineering tasks has created a need to understand their problem-solving behaviours beyond simple success metrics. While these agents demonstrate impressive…

Software Engineering · Computer Science 2025-11-04 Oorja Majgaonkar , Zhiwei Fei , Xiang Li , Federica Sarro , He Ye

Evaluating AI agents within complex, interactive environments that mirror real-world challenges is critical for understanding their practical capabilities. While existing agent benchmarks effectively assess skills like tool use or…

Artificial Intelligence · Computer Science 2025-08-15 Long Phan , Mantas Mazeika , Andy Zou , Dan Hendrycks

Multi-agent large language model simulations have the potential to model complex human behaviors and interactions. If the mechanics are set up properly, unanticipated and valuable social dynamics can surface. However, it is challenging to…

Multiagent Systems · Computer Science 2026-04-22 Jenny Ma , Riya Sahni , Karthik Sreedhar , Lydia B. Chilton

LMMs have shown impressive visual understanding capabilities, with the potential to be applied in agents, which demand strong reasoning and planning abilities. Nevertheless, existing benchmarks mostly assess their reasoning abilities in…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Miaosen Zhang , Qi Dai , Yifan Yang , Jianmin Bao , Dongdong Chen , Kai Qiu , Chong Luo , Xin Geng , Baining Guo

AI agents aim to solve complex tasks by combining text-based reasoning with external tool calls. Unfortunately, AI agents are vulnerable to prompt injection attacks where data returned by external tools hijacks the agent to execute…

Cryptography and Security · Computer Science 2024-11-26 Edoardo Debenedetti , Jie Zhang , Mislav Balunović , Luca Beurer-Kellner , Marc Fischer , Florian Tramèr

Large Language Models (LLMs) are becoming increasingly powerful and capable of handling complex tasks, e.g., building single agents and multi-agent systems. Compared to single agents, multi-agent systems have higher requirements for the…

Computation and Language · Computer Science 2024-08-29 Wei Wang , Dan Zhang , Tao Feng , Boyan Wang , Jie Tang

Coding agents represent a new paradigm in automated software engineering, combining the reasoning capabilities of Large Language Models (LLMs) with tool-augmented interaction loops. However, coding agents still have severe limitations.…

Software Engineering · Computer Science 2026-04-06 Tural Mehtiyev , Wesley Assunção

The rapid advancement of large language models (LLMs) has sparked growing interest in their integration into autonomous systems for reasoning-driven perception, planning, and decision-making. However, evaluating and training such agentic AI…

Artificial Intelligence · Computer Science 2026-01-26 Mohamed Amine Ferrag , Abderrahmane Lakas , Merouane Debbah

Despite their ability to understand chemical knowledge, large language models (LLMs) remain limited in their capacity to propose novel molecules with desired functions (e.g., drug-like properties). In addition, the molecules that LLMs…